A Comparison of the Antioxidant Effects Between Hydrogen Gas Inhalation and Vitamin C Supplementation in Response to a 60-Min Treadmill Exercise in Rat Gastrocnemius Muscle.

This animal study examined A Comparison of the Antioxidant Effects Between Hydrogen Gas Inhalation and Vitamin C Supplementation in Response to a 60-Min Treadmill Exercise in Rat Gastrocnemius Muscle. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: It has been suggested that hydrogen gas, as an antioxidant, can selectively scavenge hydroxyl radicals but does not affect superoxide anion's signal transduction. This is an automated editorial draft based on the abstract and requires source review before publication.

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Short-term H inhalation improves running performance and torso strength in healthy adults.

This randomized controlled trial examined Short-term H inhalation improves running performance and torso strength in healthy adults. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 7 days. The abstract reports: Breathing 4% hydrogen for 20 min per day resulted in increased peak running velocity (by up to 4.2%) as compared to air inhalation (…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Co-administration of hydrogen and metformin exerts cardioprotective effects by inhibiting pyroptosis and fibrosis in diabetic cardiomyopathy.

This animal study examined Co-administration of hydrogen and metformin exerts cardioprotective effects by inhibiting pyroptosis and fibrosis in diabetic cardiomyopathy. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: In this study, we found that hydrogen improved cardiac dysfunction and abnormal morphological structure in streptozotocin-induced diabetic mice. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation alleviates nonalcoholic fatty liver disease in metabolic syndrome rats.

This animal study examined Hydrogen inhalation alleviates nonalcoholic fatty liver disease in metabolic syndrome rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Therapy Attenuates Inflammatory Pathway Signaling in Septic Mice.

This animal study examined Hydrogen Gas Therapy Attenuates Inflammatory Pathway Signaling in Septic Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: These findings may contribute to clarifying the mechanism of action of H therapy in sepsis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of Hydrogen Gas Inhalation on Community-Dwelling Adults of Various Ages: A Single-Arm, Open-Label, Prospective Clinical Trial

This uncontrolled human study examined Effects of Hydrogen Gas Inhalation on Community-Dwelling Adults of Various Ages: A Single-Arm, Open-Label, Prospective Clinical Trial. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Investigation of oxidative stress markers such as reactive oxygen species and nitric oxide showed that their levels decreased post-treatment. This is an automated editorial draft based on the abstract and requires source review before publication.

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Different effects of hydrogen-rich water intake and hydrogen gas inhalation on gut microbiome and plasma metabolites of rats in health status.

This animal study examined Different effects of hydrogen-rich water intake and hydrogen gas inhalation on gut microbiome and plasma metabolites of rats in health status. The abstract describes Rat model; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: Pathway enrichment analysis showed that HRW intake mainly affected starch and sucrose metabolism, and DMs in HI group were mainly enriched in arginine biosynthesis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model.

This animal study examined Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation; reported duration 30 min. The abstract reports: Our results demonstrated that TMT exposure alters seizure and spatial recognition memory. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Treatment Improves Postoperative Delirium and Cognitive Dysfunction in Elderly Noncardiac Patients.

This uncontrolled human study examined Hydrogen Gas Treatment Improves Postoperative Delirium and Cognitive Dysfunction in Elderly Noncardiac Patients. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Results: Postoperative delirium occurred in 17 (24%) of 70 patients without hydrogen inhalation and in 10 (12%) of 83 patients after hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen inhalation attenuates postoperative cognitive impairment in rats.

This animal study examined Molecular hydrogen inhalation attenuates postoperative cognitive impairment in rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Many studies have found that molecular hydrogen (H2) has significant neuroprotection against acute and chronic neurological injury by regulating inflammation and apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation therapy may ameliorate amyotrophic lateral sclerosis.

This uncontrolled human study examined Hydrogen inhalation therapy may ameliorate amyotrophic lateral sclerosis. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Amyotrophic lateral sclerosis (ALS) is a motor neuron disease, a neurodegenerative disorder characterized by sporadic and progressive degenerative loss of cell bodies of both…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Anti-Inflammatory Effect of Hydrogen Gas Inhalation and Its Influence on Laser-Induced Choroidal Neovascularization in a Mouse Model of Neovascular Age-Related Macular Degeneration

This animal study examined The Anti-Inflammatory Effect of Hydrogen Gas Inhalation and Its Influence on Laser-Induced Choroidal Neovascularization in a Mouse Model of Neovascular Age-Related Macular Degeneration. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: H inhalation could alleviate CNV leakage in a laser-induced mouse CNV model, and the potential mechanism might be related to the suppression of the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen inhalation during the warm ischemia phase against lung ischemia-reperfusion injury in rat donors after cardiac death.

This animal study examined Protective effects of hydrogen inhalation during the warm ischemia phase against lung ischemia-reperfusion injury in rat donors after cardiac death. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Lung inhalation with 3% hydrogen during the warm ischemia phase attenuated lung graft IRI via NF-κB-dependent anti-inflammatory and antioxidative effects in rat donors after…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model

This animal study examined Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: H2 inhalation after shock stabilized hemodynamics and improved survival rates in an HS/R model independent of XOR. The therapeutic action of H2 was partially…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas inhalation alleviates myocardial ischemia-reperfusion injury by the inhibition of oxidative stress and NLRP3-mediated pyroptosis in rats.

This animal study examined Hydrogen gas inhalation alleviates myocardial ischemia-reperfusion injury by the inhibition of oxidative stress and NLRP3-mediated pyroptosis in rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: We found that oxidative stress and NLRP3 mediated pyroptosis are the important mechanisms for hydrogen to alleviate myocardial I/R injury, and we also confirmed…. This is an automated editorial draft based on the abstract and requires source review before publication.

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