The Benefit of Hydrogen Gas as an Adjunctive Therapy for Chronic Obstructive Pulmonary Disease
This uncontrolled human study examined The Benefit of Hydrogen Gas as an Adjunctive Therapy for Chronic Obstructive Pulmonary Disease. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 30 min. The abstract reports: Recent studies suggest that hydrogen gas possesses anti-inflammatory, antioxidant, and anti-apoptotic properties. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHigh Concentration Hydrogen Mitigates Sepsis-Induced Acute Lung Injury in Mice by Alleviating Mitochondrial Fission and Dysfunction.
This animal study examined High Concentration Hydrogen Mitigates Sepsis-Induced Acute Lung Injury in Mice by Alleviating Mitochondrial Fission and Dysfunction. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Lungs are among the organs that are affected in MOF, resulting in acute lung injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation attenuates lung contusion after blunt chest trauma in mice.
This animal study examined Hydrogen inhalation attenuates lung contusion after blunt chest trauma in mice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen inhalation therapy significantly mitigated inflammatory responses associated with lung contusion in mice. Hydrogen inhalation therapy may be a supplemental therapeutic strategy for treating…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice.
This animal study examined Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response most probably through the TLR4-NF-κB pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Attenuates Endotoxin-Induced Lung Injury by Activating Thioredoxin 1 and Decreasing Tissue Factor Expression.
This animal study examined Hydrogen Attenuates Endotoxin-Induced Lung Injury by Activating Thioredoxin 1 and Decreasing Tissue Factor Expression. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: LPS-stimulated THP-1 and HUVEC-C cells and showed that hydrogen decreases TF expression and MMP-9 activity, which were abolished by the Trx1 inhibitor, PX12. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe effects of inhaling hydrogen gas on macrophage polarization, fibrosis, and lung function in mice with bleomycin-induced lung injury.
This animal study examined The effects of inhaling hydrogen gas on macrophage polarization, fibrosis, and lung function in mice with bleomycin-induced lung injury. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results suggest that hydrogen inhalation inhibits the deterioration of respiratory physiological function and alveolar fibrosis in this model of lung injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients.
This observational study examined Hydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients. The abstract describes Human participants; sample size 10; hydrogen delivered as hydrogen inhalation; reported duration 45 min. The abstract reports: A single inhalation of hydrogen for 45 min attenuated inflammatory status in airways in patients with asthma and COPD. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.
This uncontrolled human study examined Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: We recently demonstrated that inhaled hydrogen reduced transplant-induced lung injury and induced heme oxygenase (HO)-1. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAttenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival.
This animal study examined Attenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The study highlights that continuous inhalation of hydrogen gas at a 2 % concentration for 24 h can be a potent intervention in the geriatric population…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation reduced epithelial apoptosis in ventilator-induced lung injury via a mechanism involving nuclear factor-kappa B activation.
This animal study examined Hydrogen inhalation reduced epithelial apoptosis in ventilator-induced lung injury via a mechanism involving nuclear factor-kappa B activation. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: We recently demonstrated the inhalation of hydrogen gas, a novel medical therapeutic gas, ameliorates ventilator-induced lung injury (VILI); however, the molecular mechanisms by which…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtection by Inhaled Hydrogen Therapy in a Rat Model of Acute Lung Injury can be Tracked in vivo Using Molecular Imaging
This animal study examined Protection by Inhaled Hydrogen Therapy in a Rat Model of Acute Lung Injury can be Tracked in vivo Using Molecular Imaging. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results suggest the potential utility of these SPECT biomarkers for in vivo assessment of key cellular pathways in the pathogenesis of ALI and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation protects against acute lung injury induced by hemorrhagic shock and resuscitation.
This animal study examined Hydrogen inhalation protects against acute lung injury induced by hemorrhagic shock and resuscitation. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen, administered through inhalation, may exert potent therapeutic effects against ALI induced by HS/R and attenuate the activation of inflammatory cascades. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model
This animal study examined Hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model. The abstract describes Rat model; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: These results suggest that hydrogen inhalation slows the development of COPD-like lung disease in a cigarette smoke-induced rat model. Higher concentrations of hydrogen may…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice.
This animal study examined Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen gas inhalation improves lung function and protects established airway inflammation in the allergic asthmatic mice model which may be associated with the inhibition…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation enhances alveolar macrophage phagocytosis in an ovalbumin-induced asthma model
This animal study examined Hydrogen gas inhalation enhances alveolar macrophage phagocytosis in an ovalbumin-induced asthma model. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Our findings demonstrated that hydrogen gas inhalation enhanced alveolar macrophage phagocytosis in OVA-induced asthmatic mice, which may be associated with the antioxidant effects of…. This is an automated editorial draft based on the abstract and requires source review before publication.
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