High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner
This animal study examined High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Results showed that 66.7 % hydrogen alleviated lung pathological changes and pulmonary edema caused by LPS, and reduced the degree of ALI by inhibiting…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation attenuated bleomycin‐induced pulmonary fibrosis by inhibiting transforming growth factor‐β1 and relevant oxidative stress and epithelial‐to‐mesenchymal transition
This uncontrolled human study examined Hydrogen inhalation attenuated bleomycin‐induced pulmonary fibrosis by inhibiting transforming growth factor‐β1 and relevant oxidative stress and epithelial‐to‐mesenchymal transition. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: • What is the central question of this study? The aim was to explore the effects and underlying mechanisms of H on bleomycin-induced pulmonary…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhaled hydrogen gas therapy for prevention of testicular ischemia/reperfusion injury in rats.
This animal study examined Inhaled hydrogen gas therapy for prevention of testicular ischemia/reperfusion injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Our results showed that inhalation of 2% H(2) gas may be a promising therapy with anti-apoptotic and anti-oxidant properties in cases of testicular ischemia/reperfusion…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation ameliorates LPS-induced BPD by inhibiting inflammation via regulating the TLR4-NFκB-IL6/NLRP3 signaling pathway in the placenta.
This animal study examined Hydrogen gas inhalation ameliorates LPS-induced BPD by inhibiting inflammation via regulating the TLR4-NFκB-IL6/NLRP3 signaling pathway in the placenta. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: H inhalation ameliorates LPS-induced BPD by inhibiting excessive inflammatory cytokines and chemokines via the TLR4-NFκB-IL6/NLRP3 signaling pathway in placenta and may be a potential…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation enhances autophagy via the AMPK/mTOR pathway, thereby attenuating doxorubicin-induced cardiac injury.
This animal study examined Hydrogen inhalation enhances autophagy via the AMPK/mTOR pathway, thereby attenuating doxorubicin-induced cardiac injury. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: These results suggest that hydrogen inhalation can activate autophagy through the AMPK/mTOR pathway and protect against myocardial injury induced by doxorubicin. Hydrogen inhalation therapy…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Inhalation Protects against Ototoxicity Induced by Intravenous Cisplatin in the Guinea Pig.
This animal study examined Hydrogen Inhalation Protects against Ototoxicity Induced by Intravenous Cisplatin in the Guinea Pig. The abstract describes Animal model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Ototoxicity may be reduced by co-administration of an otoprotective agent, but the results in humans have so far been modest. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRandomized double-blind placebo-controlled trial of hydrogen inhalation for Parkinson’s disease: a pilot study
This randomized controlled trial examined Randomized double-blind placebo-controlled trial of hydrogen inhalation for Parkinson’s disease: a pilot study. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: This pilot study revealed that the inhalation of molecular hydrogen gas was safe, but did not show any beneficial effects in patients with PD. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRealizing brain therapy with “smart medicine”: mechanism and case report of molecular hydrogen inhalation for Parkinson’s disease.
This case report or case series examined Realizing brain therapy with “smart medicine”: mechanism and case report of molecular hydrogen inhalation for Parkinson’s disease. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 35 years. The abstract reports: Fox Foundation has been funding research on Parkinson's disease for 35 years, but has yet to find a cure. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen gas inhalation on L-DOPA-induced dyskinesia.
This uncontrolled human study examined Effects of hydrogen gas inhalation on L-DOPA-induced dyskinesia. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEmerging mechanisms and novel applications of hydrogen gas therapy.
This narrative review examined Emerging mechanisms and novel applications of hydrogen gas therapy. The abstract describes Published literature review; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation therapy may not work sufficiently to mitigate oxidative stress induced with REBOA
This animal study examined Hydrogen gas inhalation therapy may not work sufficiently to mitigate oxidative stress induced with REBOA. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation; reported duration 180 minutes. The abstract reports: Survival analysis showed no significant differences between the two groups (control vs. hydrogen, 4/5 vs. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhaled hydrogen gas therapy for prevention of noise-induced hearing loss through reducing reactive oxygen species.
This animal study examined Inhaled hydrogen gas therapy for prevention of noise-induced hearing loss through reducing reactive oxygen species. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation. The abstract reports: All animals underwent measurements for auditory brainstem response after the noise exposure; the results revealed that there was a better improvement in the threshold…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe impact of hydrogen inhalation therapy on blood reactive oxygen species levels: A randomized controlled study
This randomized controlled trial examined The impact of hydrogen inhalation therapy on blood reactive oxygen species levels: A randomized controlled study. The abstract describes Human participants; sample size 37; hydrogen delivered as hydrogen inhalation. The abstract reports: Their results were compared to those of the control group participants who did not undergo HIT. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRole of molecular hydrogen in obesity treatment: modulation of GLP-1, irisin, and PGC-1α for improved metabolism.
This meta-analysis examined Role of molecular hydrogen in obesity treatment: modulation of GLP-1, irisin, and PGC-1α for improved metabolism. The abstract describes Published literature review; sample size 1088; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: Dihydrogen is a medical gas with extensively documented antioxidant, anti-inflammatory, and signaling properties, validated in over 1000 studies across more than 100 disease models,1…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreiTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice.
This uncontrolled human study examined iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: The results of the H&E, and Nissl staining indicated that the CLP mice had a significant brain injury, which was characterized by aggravated pathological…. This is an automated editorial draft based on the abstract and requires source review before publication.
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