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In a laboratory model, bulk-RNA seq indicates that H₂ and alkaline pH increase periosteal cell proliferation, while Mg2+ may mainly enhance extracellular matrix formation and cell adhesion in the femur ex vivo. These findings from a laboratory model add evidence supporting molecular…
Read ArticleThe results demonstrated that H₂ attenuated HT22 cell injury, which would be confirmed by the improved cell survival rate and decreased levels of lactate dehydrogenase. The authors concluded…
Read ArticleIn Hydrogen was found to suppress apoptosis, reduce oxidative stress levels, and ameliorate inflammatory responses in the liver tissue of DOX mice, hydrogen treatment significantly mitigated DOX-induced liver…
Read ArticleIn H₂ was administered to assess its effects on BPD rats, while hydrogen-rich medium was used to treat RLE-6TN cells to evaluate cell viability, H₂ treatment ameliorated lung…
Read ArticleIn The researchers employed a translational approach using both in vitro and in vivo models of IH, H₂ administration attenuated vascular remodeling, reducing medial thickening and collagen deposition,…
Read ArticleIn ATG9B was knocked down using siRNA in vitro and AAV-shRNA in the hippocampal CA1 region in vivo to clarify its function, H₂ inhalation increased 7-day survival in…
Read ArticleIn In vitro experiments further confirmed its effects on HaCaT keratinocytes, pathway enrichment analysis indicated that biotin metabolism was the potential target pathway. These findings from a laboratory…
Read ArticleIn exposure to hydrogen increased the proportions of active pro-embryogenic cells and normal somatic embryos, exogenous hydrogen application significantly reduced ROS levels and enhanced antioxidant enzyme activity in…
Read ArticleIn a laboratory model, hydrogen-rich medium can effectively attenuate LPS-induced dysfunction of intestinal epithelial barrier in human Caco2 cells by ameliorating cell viability as well as regulating claudin-1…
Read ArticleIn The mRNA levels of ANP and BNP were examined by PCR in vitro, lPS induced cardiac dysfunction; hydrogen therapy improved cardiac function after LPS challenge. The authors…
Read ArticleIn The objective of this study was to investigate the protection of hydrogen-rich medium (HRM) on Cr(VI)-induced ER stress and autophagy in DF-1 cells, however, there are few…
Read ArticleIn Endothelial cells were seeded in 6-well plates and randomly divided into 4 groups (n = 42 each):control (A), hydrogen-rich medium (B), LPS (C) and LPS+hydrogen-rich medium (D),…
Read ArticleThe researchers found that hydrogen-rich medium could inhibit adhesion of monocytes to endothelial cells and decrease levels of adhesion molecules, whereas the levels of transepithelial/endothelial electrical resistance values…
Read ArticleIn a laboratory model, treatment with hydrogen reduced Ang II- or AAC-induced oxidative stress, which was reflected by diminishing the induction of reactive oxygen species (ROS) in Ang…
Read ArticleIn a laboratory model, compared with LPS, there was an obvious reduction in the conglutination of LPS+H₂ cells, a reduction in VCAM-1, ICAM-1, and E-selectin levels, and a…
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