Hydrogen saline treatment attenuates hyperoxia-induced retinopathy by inhibition of oxidative stress and reduction of VEGF expression.

This animal study examined Hydrogen saline treatment attenuates hyperoxia-induced retinopathy by inhibition of oxidative stress and reduction of VEGF expression. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 5 days. The abstract reports: Hydrogen saline may be a potential treatment for hyperoxia-induced retinopathy that acts via the inhibition of oxidative stress and the reduction of VEGF expression. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen saline prevents selenite-induced cataract in rats.

This animal study examined Hydrogen saline prevents selenite-induced cataract in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 2 weeks. The abstract reports: This is an initial report showing that hydrogen saline can prevent selenite-induced cataract in rats. It acts via maintaining antioxidant enzymes and GSH, protecting…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline as an Innovative Therapy for Cataract: A Hypothesis

This uncontrolled human study examined Hydrogen-Rich Saline as an Innovative Therapy for Cataract: A Hypothesis. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline reduces cell death through inhibition of DNA oxidative stress and overactivation of poly (ADP-ribose) polymerase-1 in retinal ischemia-reperfusion injury.

This animal study examined Hydrogen-rich saline reduces cell death through inhibition of DNA oxidative stress and overactivation of poly (ADP-ribose) polymerase-1 in retinal ischemia-reperfusion injury. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Overactivation of poly (ADP-ribose) polymerase 1 (PARP-1), as a result of sustained DNA oxidation in ischemia-reperfusion injury, triggers programmed cell necrosis and apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect of molecular hydrogen, a novelly-established antioxidant, on the retinal degeneration of hereditary retinitis pigmentosa: an study.

This animal study examined Effect of molecular hydrogen, a novelly-established antioxidant, on the retinal degeneration of hereditary retinitis pigmentosa: an study. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The ERG amplitude in mice from the control and H intervention groups showed no statistical differences ( 0.05). This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas as an Exotic Performance-Enhancing Agent: Challenges and Opportunities.

This study protocol examined Hydrogen Gas as an Exotic Performance-Enhancing Agent: Challenges and Opportunities. The abstract describes Planned or registered research population; hydrogen delivered as hydrogen water and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: H is a newfangled and rather effective performance-enhancing agent, yet its promising ergogenic potency has to be further validated and characterized in more well-controlled,…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline promotes motor functional recovery following peripheral nerve autografting in rats.

This animal study examined Hydrogen-rich saline promotes motor functional recovery following peripheral nerve autografting in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The data showed that rats receiving hydrogen-rich saline achieved better axonal regeneration and functional recovery than those receiving normal saline. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline Accelerates Diabetic Wound Healing in Vivo and Its Interaction with the Renin-Angiotensin System Pathway.

This animal study examined Hydrogen-Rich Saline Accelerates Diabetic Wound Healing in Vivo and Its Interaction with the Renin-Angiotensin System Pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: This study confirmed that HRS promotes diabetic wound healing by alleviating oxidative stress and inflammation, and these effects may be mechanistically associated with the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen saline on diabetic retinopathy in a streptozotocin-induced diabetic rat model.

This animal study examined Protective effects of hydrogen saline on diabetic retinopathy in a streptozotocin-induced diabetic rat model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 4 weeks. The abstract reports: Our preliminary studies indicated that H(2) saline may have potentials in the clinical treatment of diabetic retinopathy. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline protects rat from oxygen glucose deprivation and reperusion-induced apoptosis through VDAC1 via Bcl-2.

This animal study examined Hydrogen-rich saline protects rat from oxygen glucose deprivation and reperusion-induced apoptosis through VDAC1 via Bcl-2. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS ameliorated OGD/RP-induced PC-12 cell apoptosis and provided a novel treatment option for ischemia. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ.

This animal study examined Hydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The present study evaluated the effects of H2 on NAFLD in rats and concluded that H2‑rich saline had significant therapeutic effects on NAFLD induced…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen-rich saline against erectile dysfunction in a streptozotocin induced diabetic rat model.

This animal study examined Protective effects of hydrogen-rich saline against erectile dysfunction in a streptozotocin induced diabetic rat model. The abstract describes Rat model; sample size 8; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 8 weeks. The abstract reports: Hydrogen-rich saline effectively improved erectile function in a streptozotocin induced diabetic rat model of erectile dysfunction. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline prevents bone loss in diabetic rats induced by streptozotocin.

This animal study examined Hydrogen-rich saline prevents bone loss in diabetic rats induced by streptozotocin. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results indicate that the systemic delivery of hydrogen saline water, which is safe and well tolerated, preserves bone volume and decreases fracture risks…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline reverses oxidative stress, cognitive impairment, and mortality in rats submitted to sepsis by cecal ligation and puncture.

This animal study examined Hydrogen-rich saline reverses oxidative stress, cognitive impairment, and mortality in rats submitted to sepsis by cecal ligation and puncture. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: These findings indicate that HRS could attenuate the consequences of sepsis induced by cecal ligation and puncture in rats, at least in part, by…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline Ameliorates Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice Via the Nrf2-ARE Signaling Pathway.

This animal study examined Hydrogen-Rich Saline Ameliorates Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice Via the Nrf2-ARE Signaling Pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: We found that HRS reduced the severity of EAE in mice and alleviated inflammation and demyelination. This is an automated editorial draft based on the abstract and requires source review before publication.

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