Therapeutic efficacy of hydrogen‑rich saline alone and in combination with PI3K inhibitor in non‑small cell lung cancer.
This uncontrolled human study examined Therapeutic efficacy of hydrogen‑rich saline alone and in combination with PI3K inhibitor in non‑small cell lung cancer. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. The abstract reports: Similarly, the results of the present study demonstrated that administration of the two agents in combination may inhibit phospho‑Akt activity, and reduce expression of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen: an advanced and safest gas option for cancer treatment.
This uncontrolled human study examined Hydrogen: an advanced and safest gas option for cancer treatment. The abstract describes Human participants; hydrogen delivered as hydrogen water and hydrogen inhalation and hydrogen-rich saline. The abstract reports: Currently available cancer treatment options, such as surgery, chemotherapy, radiation, and immunotherapy, are limited, and the results could be unsatisfactory due to systemic toxicity…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreControlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis.
This animal study examined Controlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and hydrogen-rich saline. The abstract reports: We find that the localized release of hydrogen increases the expression level of P53 tumor suppressor proteins, as demonstrated by the RNA sequencing and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich saline on monocrotaline-induced pulmonary hypertension in a rat model.
This animal study examined Protective effects of hydrogen-rich saline on monocrotaline-induced pulmonary hypertension in a rat model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These results suggest that hydrogen-rich saline ameliorates the progression of pulmonary hypertension induced by monocrotaline in rats, which may be associated with its antioxidant…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Attenuates Chronic Allodynia after Bone Fractures via Reducing Spinal CXCL1/CXCR2-Mediated Iron Accumulation in Mice.
This animal study examined Hydrogen-Rich Saline Attenuates Chronic Allodynia after Bone Fractures via Reducing Spinal CXCL1/CXCR2-Mediated Iron Accumulation in Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These findings identify that hydrogen-rich saline confers protection against fracture-caused chronic allodynia via spinal down-modulation of CXCL1-dependent TfR1-mediated iron accumulation in mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates ischemia-reperfusion injury in skeletal muscle.
This animal study examined Hydrogen-rich saline attenuates ischemia-reperfusion injury in skeletal muscle. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS seems to be effective in attenuating IR injury in skeletal muscle via its antioxidant, anti-apoptosis, and anti-autophagy effect. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo.
This animal study examined Hydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results showed that the number of senescence-associated β-galactosidase (SA-β-Gal) positive cells was reduced in BMSCs from rats treated with HRS. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates steroid-associated femoral head necrosis through inhibition of oxidative stress in a rabbit model.
This animal study examined Hydrogen-rich saline attenuates steroid-associated femoral head necrosis through inhibition of oxidative stress in a rabbit model. The abstract describes Rabbit model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: A growing body of evidence suggests that hydrogen is a novel, selective antioxidant that exerts a protective effect against organ damage. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRETRACTED: Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer’s disease
This animal study examined RETRACTED: Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer’s disease. The abstract describes Rat model; sample size 18; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 10 days. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer’s disease by reduction of oxidative stress.
This animal study examined Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer’s disease by reduction of oxidative stress. The abstract describes Rat model; sample size 84; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 14 days. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP levels.
This animal study examined Hydrogen-rich saline attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP levels. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Our results suggest that HS attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP…. This is an automated editorial draft based on the abstract and requires source review before publication.
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