Molecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens.
This animal study examined Molecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: We found that HRS administration was able to inhibit the acquisition and transfer of 0.1 and 0.5 mg/kg METH-induced behavioral sensitization to a certain extent,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich water on depressive-like behavior in mice.
This uncontrolled human study examined Effects of hydrogen-rich water on depressive-like behavior in mice. The abstract describes Human participants; hydrogen delivered as hydrogen water and hydrogen-rich saline. The abstract reports: Emerging evidence suggests that neuroinflammation and oxidative stress may be major contributors to major depressive disorder (MDD). This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice.
This animal study examined Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 3 days. The abstract reports: We found that HRS administration significantly reduced body weight loss, jumping behavior and wet-dog shakes in mice underwent naloxone-precipitated withdrawal, and attenuated anxiety-like behaviors…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Regulates Microglial Phagocytosis and Restores Behavioral Deficits Following Hypoxia-Ischemia Injury in Neonatal Mice via the Akt Pathway.
This animal study examined Hydrogen-Rich Saline Regulates Microglial Phagocytosis and Restores Behavioral Deficits Following Hypoxia-Ischemia Injury in Neonatal Mice via the Akt Pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The result showed that HS administration alleviated HI-induced edema, infract volume and cellular apoptosis within the cortex of neonatal mice. Accompanying these indices of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates postoperative liver failure after major hepatectomy in rats.
This animal study examined Hydrogen-rich saline attenuates postoperative liver failure after major hepatectomy in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HS attenuates the massive hepatectomy induced liver injury not only by attenuating oxidative damage, but also by reducing the production of inflammatory cytokines, such…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Attenuates Acute Kidney Injury After Liver Transplantation via Activating p53-Mediated Autophagy.
This animal study examined Hydrogen-Rich Saline Attenuates Acute Kidney Injury After Liver Transplantation via Activating p53-Mediated Autophagy. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS is able to protect against AKI after liver transplantation partly by reducing apoptosis, which is possibly involved in the modulation of p53-mediated autophagy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConcomitant inhibition of oxidative stress and angiogenesis by chronic hydrogen‐rich saline and N‐acetylcysteine treatments improves systemic, splanchnic and hepatic hemodynamics of cirrhotic rats
This animal study examined Concomitant inhibition of oxidative stress and angiogenesis by chronic hydrogen‐rich saline and N‐acetylcysteine treatments improves systemic, splanchnic and hepatic hemodynamics of cirrhotic rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 1 month. The abstract reports: Both hydrogen-rich saline and N-acetylcysteine alleviate portal hypertension, the severity of portosystemic collaterals, mesenteric angiogenesis, hepatic endothelial dysfunction and intrahepatic resistance in cirrhotic rats.…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects against hepatic injury induced by ischemia-reperfusion and laparoscopic hepatectomy in swine.
This animal study examined Hydrogen-rich saline protects against hepatic injury induced by ischemia-reperfusion and laparoscopic hepatectomy in swine. The abstract describes Porcine model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS treatment may exert a protective effect against I/R and hepatectomy-induced hepatic damage by reducing oxidative stress, suppressing the inflammatory response and promoting liver…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects against liver injury in rats with obstructive jaundice.
This animal study examined Hydrogen-rich saline protects against liver injury in rats with obstructive jaundice. The abstract describes Rat model; sample size 56; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline attenuates BDL-induced liver damage, possibly by the reduction of inflammation and oxidative stress and the inhibition of the ERK1/2 pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects against small-scale liver ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress.
This animal study examined Hydrogen-rich saline protects against small-scale liver ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline. The abstract reports: We observed that HRS visibly improved ischemia-reperfusion injury (IRI) by reducing various parameters of ERS stress as evidenced by down-regulation of the mRNA as…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe protective role of hydrogen-rich saline in experimental liver injury in mice.
This animal study examined The protective role of hydrogen-rich saline in experimental liver injury in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HS could protect against liver injury and also inhibit the processes leading to liver cirrhosis and hepatocyte compensatory proliferation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInfluence of Hydrogen-rich Saline on Hepatocyte Autophagy During Laparoscopic Liver Ischaemia-reperfusion Combined Resection Injury in Miniature Pigs.
This animal study examined Influence of Hydrogen-rich Saline on Hepatocyte Autophagy During Laparoscopic Liver Ischaemia-reperfusion Combined Resection Injury in Miniature Pigs. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Intervention with hydrogen-rich saline could exert a protective effect against liver ischaemia-reperfusion combined resection injury through the reduction of oxidative stress and hepatocyte autophagy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of hydrogen-rich saline on apoptosis induced by hepatic ischemia reperfusion upon laparoscopic hepatectomy in miniature pigs.
This animal study examined Effect of hydrogen-rich saline on apoptosis induced by hepatic ischemia reperfusion upon laparoscopic hepatectomy in miniature pigs. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results showed that HRS treatment significantly decreased serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and total bilirubin (TBIL) activity and TUNEL-positive…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Ameliorates Hepatic Ischemia-Reperfusion Injury Through Regulation of Endoplasmic Reticulum Stress and Apoptosis.
This animal study examined Hydrogen-Rich Saline Ameliorates Hepatic Ischemia-Reperfusion Injury Through Regulation of Endoplasmic Reticulum Stress and Apoptosis. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The protective effect of HS can be attributed to ER stress and apoptosis inhibition. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSaturated hydrogen saline attenuates endotoxin-induced acute liver dysfunction in rats.
This animal study examined Saturated hydrogen saline attenuates endotoxin-induced acute liver dysfunction in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. This is an automated editorial draft based on the abstract and requires source review before publication.
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