Hydrogen-rich saline protects against intestinal ischemia/reperfusion injury in rats.

This animal study examined Hydrogen-rich saline protects against intestinal ischemia/reperfusion injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Luminal injection of hydrogen-rich solution attenuates intestinal ischemia-reperfusion injury in rats.

This animal study examined Luminal injection of hydrogen-rich solution attenuates intestinal ischemia-reperfusion injury in rats. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen; reported duration 90 min. The abstract reports: Luminal injection of hydrogen-rich solution can reduce oxidative stress and consequently ameliorate ischemic-reperfusion injury. Hydrogen-containing solution can be a novel and promising luminal preservation…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen-rich saline on ulcerative colitis rat model.

This animal study examined Protective effects of hydrogen-rich saline on ulcerative colitis rat model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Antioxidative hydrogen-rich saline effectively protected the rats from UC, which might be, at least in part, because of inhibition of vascular endothelial growth factor. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhaled hydrogen ameliorates endotoxin-induced bowel dysfunction.

This uncontrolled human study examined Inhaled hydrogen ameliorates endotoxin-induced bowel dysfunction. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: This study showed the protective effects of hydrogen inhalation on LPS-induced septic ileus through inhibition of inflammation in the muscularis propria. These inhibitory effects…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation therapy alone may not alleviate intestinal mucosal damage in NOMI without total‐layer necrosis: An experimental swine model study

This animal study examined Hydrogen inhalation therapy alone may not alleviate intestinal mucosal damage in NOMI without total‐layer necrosis: An experimental swine model study. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Although critically ill conditions can trigger NOMI, the model used in this study did not involve transmural necrosis. Under such conditions, hydrogen inhalation therapy…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Water Mitigates LPS-Induced Chronic Intestinal Inflammatory Response in Rats via Nrf-2 and NF-κB Signaling Pathways.

This animal study examined Hydrogen-Rich Water Mitigates LPS-Induced Chronic Intestinal Inflammatory Response in Rats via Nrf-2 and NF-κB Signaling Pathways. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: The obtained results show that hydrogen-rich water significantly increased the levels of superoxide dismutase and structural proteins; activated the Nrf-2 signaling pathway; downregulated the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Sirtuin Type 1 Mediates the Retinal Protective Effect of Hydrogen-Rich Saline Against Light-Induced Damage in Rats.

This animal study examined Sirtuin Type 1 Mediates the Retinal Protective Effect of Hydrogen-Rich Saline Against Light-Induced Damage in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 5 days. The abstract reports: Sirt1 mediates light-induced damage mitigation by HRS through inhibition of apoptosis and oxidant-stress. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline protects retina against glutamate-induced excitotoxic injury in guinea pig.

This in vitro or cellular study examined Hydrogen-rich saline protects retina against glutamate-induced excitotoxic injury in guinea pig. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: This result likely occurs by inhibiting the activation of glial cells, decreasing the production of the iNOS and GRP78 and promoting glutamate clearance. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Comparative Efficiency of Intraperitoneal and Intravitreous Injection of Hydrogen Rich Saline against -Methyl–Nitrosourea Induced Retinal Degeneration: A Topographic Study.

This animal study examined The Comparative Efficiency of Intraperitoneal and Intravitreous Injection of Hydrogen Rich Saline against -Methyl–Nitrosourea Induced Retinal Degeneration: A Topographic Study. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Particularly, the topographic measurements suggested that the IV delivery of HRS could alleviate MNU induced photoreceptor degeneration in the posterior retina. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of saturated hydrogen saline against blue light-induced retinal damage in rats.

This animal study examined Protective effect of saturated hydrogen saline against blue light-induced retinal damage in rats. The abstract describes Rat model; sample size 30; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 6 hours. The abstract reports: Saturated hydrogen saline could protect the retina from light-induced damage by attenuating oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.

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Postconditioning with inhaled hydrogen promotes survival of retinal ganglion cells in a rat model of retinal ischemia/reperfusion injury.

This animal study examined Postconditioning with inhaled hydrogen promotes survival of retinal ganglion cells in a rat model of retinal ischemia/reperfusion injury. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: HE and CTB tracing showed that the survival rate of RGCs in the H2-treated group was significantly higher than the rate in the I/R…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen saline treatment attenuates hyperoxia-induced retinopathy by inhibition of oxidative stress and reduction of VEGF expression.

This animal study examined Hydrogen saline treatment attenuates hyperoxia-induced retinopathy by inhibition of oxidative stress and reduction of VEGF expression. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 5 days. The abstract reports: Hydrogen saline may be a potential treatment for hyperoxia-induced retinopathy that acts via the inhibition of oxidative stress and the reduction of VEGF expression. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen saline prevents selenite-induced cataract in rats.

This animal study examined Hydrogen saline prevents selenite-induced cataract in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 2 weeks. The abstract reports: This is an initial report showing that hydrogen saline can prevent selenite-induced cataract in rats. It acts via maintaining antioxidant enzymes and GSH, protecting…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas as an Exotic Performance-Enhancing Agent: Challenges and Opportunities.

This study protocol examined Hydrogen Gas as an Exotic Performance-Enhancing Agent: Challenges and Opportunities. The abstract describes Planned or registered research population; hydrogen delivered as hydrogen water and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: H is a newfangled and rather effective performance-enhancing agent, yet its promising ergogenic potency has to be further validated and characterized in more well-controlled,…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen reduces LPS-induced neuroinflammation and promotes recovery from sickness behaviour in mice.

This animal study examined Molecular hydrogen reduces LPS-induced neuroinflammation and promotes recovery from sickness behaviour in mice. The abstract describes Mouse model; sample size 6; hydrogen delivered as injected or infused hydrogen. The abstract reports: The effect was suggested to be mediated by its free-radical scavenger properties. This is an automated editorial draft based on the abstract and requires source review before publication.

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