Hydrogen-rich saline promotes motor functional recovery following peripheral nerve autografting in rats.

This animal study examined Hydrogen-rich saline promotes motor functional recovery following peripheral nerve autografting in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The data showed that rats receiving hydrogen-rich saline achieved better axonal regeneration and functional recovery than those receiving normal saline. This is an automated editorial draft based on the abstract and requires source review before publication.

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Intravenous infusion of H2-saline suppresses oxidative stress and elevates antioxidant potential in Thoroughbred horses after racing exercise.

This animal study examined Intravenous infusion of H2-saline suppresses oxidative stress and elevates antioxidant potential in Thoroughbred horses after racing exercise. The abstract describes Animal model; sample size 6; hydrogen delivered as injected or infused hydrogen. The abstract reports: Upon intensive, exhaustive exercise, exercise-induced reactive oxygen species may exceed the antioxidant defence threshold, consequently resulting in muscular damage or late-onset chronic inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen regulates PTEN‐AKT‐mTOR signaling via ROS to alleviate peritoneal dialysis‐related peritoneal fibrosis

This uncontrolled human study examined Molecular hydrogen regulates PTEN‐AKT‐mTOR signaling via ROS to alleviate peritoneal dialysis‐related peritoneal fibrosis. The abstract describes Human participants; hydrogen delivered as injected or infused hydrogen. The abstract reports: Furthermore, it has been found that molecular hydrogen alleviate fibrosis by eliminating intracellular ROS and inhibiting the activation of the PTEN/AKT/mTOR pathway. This is an automated editorial draft based on the abstract and requires source review before publication.

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Subcutaneous injection of hydrogen gas is a novel effective treatment for type 2 diabetes.

This animal study examined Subcutaneous injection of hydrogen gas is a novel effective treatment for type 2 diabetes. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen; reported duration 4 weeks. The abstract reports: Subcutaneous injection of H significantly improves type 2 diabetes mellitus and diabetic nephropathy-related outcomes in a mouse model, supporting further consideration of subcutaneous injection…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen-rich saline against erectile dysfunction in a streptozotocin induced diabetic rat model.

This animal study examined Protective effects of hydrogen-rich saline against erectile dysfunction in a streptozotocin induced diabetic rat model. The abstract describes Rat model; sample size 8; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 8 weeks. The abstract reports: Hydrogen-rich saline effectively improved erectile function in a streptozotocin induced diabetic rat model of erectile dysfunction. This is an automated editorial draft based on the abstract and requires source review before publication.

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Therapeutic effects of hydrogen saturated saline on rat diabetic model and insulin resistant model via reduction of oxidative stress.

This animal study examined Therapeutic effects of hydrogen saturated saline on rat diabetic model and insulin resistant model via reduction of oxidative stress. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Hydrogen saturated saline may improve the insulin resistance and alleviate the symptoms of diabetes mellitus by reducing the oxidative stress and enhancing the anti-oxidant…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen improves type 2 diabetes through inhibiting oxidative stress.

This animal study examined Molecular hydrogen improves type 2 diabetes through inhibiting oxidative stress. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen; reported duration 4 weeks. The abstract reports: The results showed that in rats with T2DM, molecular hydrogen treatment decreased fasting blood glucose levels, increased hepatic glycogen synthesis and improved insulin sensitivity. This is an automated editorial draft based on the abstract and requires source review before publication.

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Adjunctive Molecular Hydrogen Therapy Modulates T Cell Markers and Reduces Anti-Ro Antibody in Refractory Oral Ulcers of Behçet’s Disease and Sjögren’s Syndrome: A Case Report.

This case report or case series examined Adjunctive Molecular Hydrogen Therapy Modulates T Cell Markers and Reduces Anti-Ro Antibody in Refractory Oral Ulcers of Behçet’s Disease and Sjögren’s Syndrome: A Case Report. The abstract describes Human participants; hydrogen delivered as injected or infused hydrogen. The abstract reports: Molecular hydrogen may aid refractory oral ulcers in Behçet's and primary Sjögren's syndromes, with clinical and immunologic benefits. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of Molecular Hydrogen on Methamphetamine-Induced Neurotoxicity and Spatial Memory Impairment.

This animal study examined Effects of Molecular Hydrogen on Methamphetamine-Induced Neurotoxicity and Spatial Memory Impairment. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: We found that the molecular hydrogen delivered by HRW consumption significantly inhibited the METH-induced spatial learning impairment and memory loss evidenced in the Barnes…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhaled molecular hydrogen reduces hippocampal neuroinflammation, glial reactivity and ameliorates memory impairment during systemic inflammation.

This uncontrolled human study examined Inhaled molecular hydrogen reduces hippocampal neuroinflammation, glial reactivity and ameliorates memory impairment during systemic inflammation. The abstract describes Human participants; hydrogen delivered as injected or infused hydrogen. The abstract reports: Sepsis is associated with numerous physiological and biochemical abnormalities that result in a life-threatening condition. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline mitigates pressure overload-induced cardiac hypertrophy and atrial fibrillation in rats via the JAK-STAT signalling pathway.

This animal study examined Hydrogen-rich saline mitigates pressure overload-induced cardiac hypertrophy and atrial fibrillation in rats via the JAK-STAT signalling pathway. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: HRS was found to mitigate cardiac hypertrophy induced by pressure overload in rats and reduce atrial fibrosis and AF which was possibly achieved via…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline alleviates inflammation and apoptosis in myocardial I/R injury via PINK-mediated autophagy.

This animal study examined Hydrogen-rich saline alleviates inflammation and apoptosis in myocardial I/R injury via PINK-mediated autophagy. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results demonstrated that treatment with hydrogen improved the myocardial infarction size of hearts, cardiac function, apoptosis and cytokine release following MI/R in rats. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline attenuates vascular smooth muscle cell proliferation and neointimal hyperplasia by inhibiting reactive oxygen species production and inactivating the Ras-ERK1/2-MEK1/2 and Akt pathways.

This animal study examined Hydrogen-rich saline attenuates vascular smooth muscle cell proliferation and neointimal hyperplasia by inhibiting reactive oxygen species production and inactivating the Ras-ERK1/2-MEK1/2 and Akt pathways. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These results showed that hydrogen-rich saline was able to attenuate FBS-induced VSMC proliferation and neointimal hyperplasia by inhibiting ROS production and inactivating the Ras-ERK1/2-MEK1/2…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Beneficial effects of hydrogen gas on porcine liver reperfusion injury with use of total vascular exclusion and active venous bypass.

This animal study examined Beneficial effects of hydrogen gas on porcine liver reperfusion injury with use of total vascular exclusion and active venous bypass. The abstract describes Porcine model; hydrogen delivered as injected or infused hydrogen; reported duration 60 minutes. The abstract reports: The solution containing hydrogen gas was safe and had remarkably protective effects on the porcine during liver I/R and may be applied in the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Cardioprotective Effect of Hydrogen-rich Saline on Isoproterenol-induced Myocardial Infarction in Rats.

This animal study examined Cardioprotective Effect of Hydrogen-rich Saline on Isoproterenol-induced Myocardial Infarction in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: From these results, hydrogen-rich saline exerts cardiovascular protective effects against isoproterenol-induced MI at least in part via interactions which evoke antioxidant and anti-inflammatory activities. This is an automated editorial draft based on the abstract and requires source review before publication.

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