Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In male C57BL/6 mice, intriguingly, hydrogen alleviated the endoplasmic reticulum stress via the autophagy pathway and also mitigated inflammation and organ injury. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleIn 2 patients, the induction of hydrogen gas production and the reduction in peripheral blood IL-1β mRNA after the test meal were not significant between days 1 (without…
Read ArticleThis narrative review examined the types of H₂ donors and their pharmacokinetics in vivo. There are various methods of administration of H₂, mainly including inhaling hydrogen gas, drinking…
Read ArticleIn Hydroxyl radicals play an important role in ionizing radiation-induced cellular damage, while hydrogen can selectively reduce hydroxyl radicals in vitro, it is concluded that hydrogen has a…
Read ArticleIn rats, hRS and HBO could all decrease the release of immflammatory cytokines in lung tissue, reduce accumulation of oxidative products and alleviate apoptosis of pulmoanry cells, and…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Although it is difficult to construe the molecular mechanism of hydrogen's biomedical effect, an increasing number of studies have been…
Read ArticleIn male Sprague-Dawley rats, h(2)-rich saline treatment improved the cognitive deficits and reduced the degree of necrosis, apoptosis, and cell autophagy in rats. These preclinical findings add evidence…
Read ArticleIn mice, spinal cord neurons were preserved by hydrogen administration after mechanical injury in a dose-dependent manner. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn A rat CPB model and an in vitro cell hypoxia model were established, hRS treatment attenuated the inflammatory reaction,brain tissue EB content was significantly reduced and significantly…
Read ArticleIn mice, the present study was designed to investigate whether hydrogen-rich saline (HS) attenuates HIBD in neonatal mice and whether the observed protection is associated with reduced endoplasmic…
Read ArticleThe researchers found that the expression of LC3 was increased after OGD/R which can be further enhanced by H₂ and RAP treatment, but treatment with 3-MA was opposite.…
Read ArticleIn 6 patients, likewise, serum ƒ(HMA) after administration of hydrogen-enriched dialysate (65.75 ± 7.52%) was significantly higher than that after standard dialysate (62.44 ± 7.66%). These findings add…
Read ArticleIn rats, hydrogen-rich saline plays a protective role in ANP-induced AHI through inhibiting inflammation and apoptosis, involving JNK and p38 MAPK-dependent reactive oxygen species. These preclinical findings add…
Read ArticleThese findings from a laboratory model add evidence supporting molecular hydrogen's biological and therapeutic potential in the model studied.
Read Article