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In rats, hydrogen-rich saline treatment significantly attenuated lung injury as indicated by significantly improved histological changes in lung, significantly reduced index of quantitative assessment (IQA), MDA content and lung coefficient (all P<0.05). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn rats, histologically, significant increases were found in glomerular adhesion, cardiac fibrosis, number of ED-1 (CD68)-positive cells and nitrotyrosine staining in the contralateral kidney and the heart. These…
Read ArticleThe researchers found that the proportion of terminal PD-1+ CD8+ T cells was reduced in 35 out of 55 patients(63.6%)and was increased in 39 out of 55 patients(70.9%)after…
Read ArticleIn Sprague Dawley rats, compared with those in burn group, the protein expressions of HMGB1 of rats in hydrogen-rich saline group at PIH 6, 24, and 72 were…
Read ArticleIn rats, compared with PHN group,the rats in the PHN-H₂ group and PHN-H₂-Rap group showed increased PWT,decreased levels of TNF-α,IL-1β and IL-6,further up-regulated expressions of LC3 and beclin…
Read ArticleIn rats, resuscitation with HS could protect liver of severely scalded rats with delayed resuscitation possibly by reducing infiltration of neutrophils, thus lowering the content of inflammatory cytokines,…
Read ArticleIn Endothelial cells were seeded in 6-well plates and randomly divided into 4 groups (n = 42 each):control (A), hydrogen-rich medium (B), LPS (C) and LPS+hydrogen-rich medium (D),…
Read ArticleIn female Wistar rats, hRS eyedrops group and HRS intraperitoneal injection group can relieve the signs of dry eye, improve the pathological damage of cornea and conjunctiva, and…
Read ArticleIn male Sprague Dawley rats, hydrogen-rich saline can attenuate global cerebral I/R injure through inhibiting JNK, reducing the expression of FOXO3a. These preclinical findings add evidence supporting molecular…
Read ArticleIn male Sprague-Dawley rats, hydrogen-rich saline can reduce myocardial reperfusion injury and improve heart function. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes…
Read ArticleIn male Sprague-Dawley rats, hydrogen-rich saline may decrease cellular apoptosis and attenuate myocardial reperfusion injury through inhibiting endoplasmic reticulum stress. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn mice, hE staining showed that there was significantly aggravated intestinal pathological injury in the mice of sepsis group; compared with sepsis group, the pathology was significantly less…
Read ArticleIn mice, the 7-day survival rate of severe sepsis mice was 0; the 7-day survival rate was increased to 60% in hydrogen treatment group, with statistical significance in…
Read ArticleIn male C57BL/6 mice, the survival rate of animals increased significantly after propofol or hydrogen-rich treatment, and the combined treatment can further increase survival rate to 90%, 75%,…
Read ArticleIn male Sprague-Dawley rats, saturated hydrogen saline prevents the degradation of elastin in vessel wall and ameliorates the formation and development of AAA, which may be associated with…
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