The combination of hydrogen gas and hydrogen-rich solution does not protect against ischemic spinal cord injury in rabbits

This animal study examined The combination of hydrogen gas and hydrogen-rich solution does not protect against ischemic spinal cord injury in rabbits. The abstract describes Rabbit model; hydrogen delivered as injected or infused hydrogen. The abstract reports: These results suggest that the combination of 1.2% H gas inhalation and administration of a hydrogen-rich solution does not protect against ischemic spinal cord…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen attenuates neuropathic pain in mice.

This animal study examined Molecular hydrogen attenuates neuropathic pain in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 3 weeks. The abstract reports: Immunohistochemical staining for the oxidative stress marker, 4-hydroxy-2-nonenal and 8-hydroxydeoxyguanosine, showed that hydrogen administration suppressed oxidative stress induced by ligation in the spinal cord…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Estimation of the hydrogen concentration in rat tissue using an airtight tube following the administration of hydrogen via various routes.

This animal study examined Estimation of the hydrogen concentration in rat tissue using an airtight tube following the administration of hydrogen via various routes. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Following inhalation of hydrogen gas, the hydrogen concentration was found to be significantly increased at 30 minutes and maintained the same level thereafter. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas is ineffective in moderate and severe neonatal hypoxia-ischemia rat models.

This animal study examined Hydrogen gas is ineffective in moderate and severe neonatal hypoxia-ischemia rat models. The abstract describes Rat model; sample size 32; hydrogen delivered as hydrogen inhalation. The abstract reports: In MCAO in adult rats, H(2) gas therapy demonstrated a trend of beneficial effect. This is an automated editorial draft based on the abstract and requires source review before publication.

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Pre-inhalation of hydrogen-rich gases protect against caerulein-induced mouse acute pancreatitis while enhance the pancreatic Hsp60 protein expression

This animal study examined Pre-inhalation of hydrogen-rich gases protect against caerulein-induced mouse acute pancreatitis while enhance the pancreatic Hsp60 protein expression. The abstract describes Mouse model; sample size 80; hydrogen delivered as injected or infused hydrogen. The abstract reports: Pre-inhalation of hydrogen-rich gases have a good protective effect on AP mice, and the possible mechanisms of reduced oxidative stress and the early increased…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline inhibits NLRP3 inflammasome activation and attenuates experimental acute pancreatitis in mice.

This animal study examined Hydrogen-rich saline inhibits NLRP3 inflammasome activation and attenuates experimental acute pancreatitis in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Increasing evidence has demonstrated that reactive oxygen species (ROS) induces oxidative stress and plays a crucial role in the pathogenesis of acute pancreatitis (AP). This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline ameliorates the severity of l-arginine-induced acute pancreatitis in rats.

This animal study examined Hydrogen-rich saline ameliorates the severity of l-arginine-induced acute pancreatitis in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These results indicate that hydrogen treatment has a protective effect against AP, and the effect is possibly due to its ability to inhibit oxidative…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The effects of hydrogen-rich saline on the contractile and structural changes of intestine induced by ischemia-reperfusion in rats.

This animal study examined The effects of hydrogen-rich saline on the contractile and structural changes of intestine induced by ischemia-reperfusion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: These results suggest that hydrogen treatment has a protective effect against intestinal contractile dysfunction and damage induced by intestinal I/R. This protective effect is…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of hydrogen-rich saline on taurocholate-induced acute pancreatitis in rat.

This animal study examined Effects of hydrogen-rich saline on taurocholate-induced acute pancreatitis in rat. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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The reason for the amelioration of N-methyl-N-nitrosourea-induced retinitis pigmentosa in rats by hydrogen-rich saline.

This animal study examined The reason for the amelioration of N-methyl-N-nitrosourea-induced retinitis pigmentosa in rats by hydrogen-rich saline. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS can effectively keep microglia activation induced by MNU to an appropriate extent, while upregulate Sirt1 in MNU-induced RP. This is an automated editorial draft based on the abstract and requires source review before publication.

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Treatment with Hydrogen-Rich Saline Delays Disease Progression in a Mouse Model of Amyotrophic Lateral Sclerosis.

This animal study examined Treatment with Hydrogen-Rich Saline Delays Disease Progression in a Mouse Model of Amyotrophic Lateral Sclerosis. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen saline water accelerates fracture healing by suppressing autophagy in ovariectomized rats.

This animal study examined Hydrogen saline water accelerates fracture healing by suppressing autophagy in ovariectomized rats. The abstract describes Rat model; hydrogen delivered as hydrogen water and hydrogen-rich saline. The abstract reports: HRW treatment activated the Keap1-Nrf2 signaling pathway to antagonize cellular stress by suppressing autophagy levels, especially at the early stage of the fracture healing…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Intake of water with high levels of dissolved hydrogen (H2) suppresses ischemia-induced cardio-renal injury in Dahl salt-sensitive rats.

This animal study examined Intake of water with high levels of dissolved hydrogen (H2) suppresses ischemia-induced cardio-renal injury in Dahl salt-sensitive rats. The abstract describes Rat model. The abstract reports: Consumption of EW by ad libitum drinking has the potential to ameliorate ischemia-induced cardio-renal injury in CKD model rats. This indicates a novel strategy…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline ameliorated LPS-induced acute lung injury via autophagy inhibition through the ROS/AMPK/mTOR pathway in mice.

This animal study examined Hydrogen-rich saline ameliorated LPS-induced acute lung injury via autophagy inhibition through the ROS/AMPK/mTOR pathway in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results showed that HRS ameliorated lipopolysaccharide-induced ALI in mice by inhibiting autophagy over-activation through ROS/AMPK/mTOR pathway. This is an automated editorial draft based on the abstract and requires source review before publication.

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Anti-obesity effect of alkaline reduced water in high fat-fed obese mice.

This animal study examined Anti-obesity effect of alkaline reduced water in high fat-fed obese mice. The abstract describes Mouse model; reported duration 12 weeks. The abstract reports: We found that ARW-fed mice significantly ameliorated adiposity: controlled body weight gain, reduced the accumulation of epididymal fats and decreased liver fats as compared…. This is an automated editorial draft based on the abstract and requires source review before publication.

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