Hydrogen-rich saline ameliorates hippocampal neuron apoptosis through up-regulating the expression of cystathionine β-synthase (CBS) after cerebral ischemia- reperfusion in rats.
This animal study examined Hydrogen-rich saline ameliorates hippocampal neuron apoptosis through up-regulating the expression of cystathionine β-synthase (CBS) after cerebral ischemia- reperfusion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 2 hr. The abstract reports: This study showed that hydrogen-rich saline ameliorates cell injury through up-regulating the expression of CBS in the hippocampus after cerebral ischemia reperfusion (I/R) in…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway.
This animal study examined Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Our results indicate that hydrogen-rich water has neuroprotective effects against TBI by reducing oxidative stress and activating the Nrf2 pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits.
This animal study examined Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits. The abstract describes Rabbit model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results suggest that treatment with hydrogen in experimental SAH rabbits could alleviate brain injury via decreasing the oxidative stress injury and brain edema.…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation improves mouse neurological outcomes after cerebral ischemia/reperfusion independent of anti-necroptosis.
This animal study examined Hydrogen inhalation improves mouse neurological outcomes after cerebral ischemia/reperfusion independent of anti-necroptosis. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation; reported duration 1 hour. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen does not Exert Neuroprotective Effects or Improve Functional Outcomes in Rats After Intracerebral Hemorrhage.
This animal study examined Hydrogen does not Exert Neuroprotective Effects or Improve Functional Outcomes in Rats After Intracerebral Hemorrhage. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 3 days. The abstract reports: Hydrogen administration without surgery has no neuroprotective effect in the blood injection rat ICH model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice.
This animal study examined Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice. The abstract describes Mouse model; sample size 1; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Activation of mast cells following intracerebral hemorrhage contributed to increase of blood-brain barrier permeability and brain edema. Hydrogen inhalation preserved blood-brain barrier disruption by…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model.
This animal study examined Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: H gas administration exerted a neuroprotective effect against early brain injury after ICH through anti-inflammatory, neuroprotective, anti-apoptotic, and antioxidative activity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats.
This uncontrolled human study examined Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Our results demonstrated that TBI-challenged rats exhibited significant brain injuries that were characterized by decreased survival rate and increased BBB permeability, brain edema, and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage.
This animal study examined Hydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Our results suggest that hydrogen inhalation exerts an acute brain-protective effect in the mouse ICH model. However, the acute hydrogen therapy alone is not…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates hippocampus endoplasmic reticulum stress after cardiac arrest in rats
This animal study examined Hydrogen-rich saline attenuates hippocampus endoplasmic reticulum stress after cardiac arrest in rats. The abstract describes Rat model; sample size 30; hydrogen delivered as hydrogen-rich saline. The abstract reports: Hydrogen-rich saline attenuates brain I/R injury may through inhibiting hippocampus ERS after cardiac arrest in rats. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats.
This animal study examined Hydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats. The abstract describes Rat model; sample size 28; hydrogen delivered as hydrogen water. The abstract reports: The present study suggests that ingestion of HRW can improve neurological function outcome in the SHRSP model. This beneficial effect may be due to…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression.
This animal study examined Neuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Recently, it has been suggested that molecular hydrogen (H) can selectively reduce the levels of hydroxyl radicals (.OH), and ameliorate oxidative and inflammatory injuries…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInfluence of oxygen concentration on the neuroprotective effect of hydrogen inhalation in a rat model of cardiac arrest
This uncontrolled human study examined Influence of oxygen concentration on the neuroprotective effect of hydrogen inhalation in a rat model of cardiac arrest. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: In this CA rat model, inhaling 2% hydrogen combined with a high concentration of oxygen improved 96-h survival, either under normothermia or under hypothermia. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline improves survival and neurological outcome after cardiac arrest and cardiopulmonary resuscitation in rats.
This uncontrolled human study examined Hydrogen-rich saline improves survival and neurological outcome after cardiac arrest and cardiopulmonary resuscitation in rats. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline treatment improved survival and neurological outcome after cardiac arrest/resuscitation in rats, which was partially mediated by reducing oxidative stress, inflammation, and apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe neuroprotective effects of intraperitoneal injection of hydrogen in rabbits with cardiac arrest.
This animal study examined The neuroprotective effects of intraperitoneal injection of hydrogen in rabbits with cardiac arrest. The abstract describes Rabbit model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Intraperitoneal injection of H2 is a novel hydrogen administration method and can reduce cerebral ischemia-reperfusion injury and improve the prognosis of cardiopulmonary cerebral resuscitation…. This is an automated editorial draft based on the abstract and requires source review before publication.
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