Hydrogen-rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus-activated kinase 2/signal transducer and activator of transcription 3 signaling pathway.

This animal study examined Hydrogen-rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus-activated kinase 2/signal transducer and activator of transcription 3 signaling pathway. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: The HRS treatment resulted in the significant upregulation of malonyl dialdehyde (MDA) and myeloperoxidase (MPO), whilesuperoxide dismutase (SOD) levels were significantly downregulated, compared with…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The protective effects of hydrogen on HO-1 expression in the brainafter focal cerebral ischemia reperfusion in rats.

This animal study examined The protective effects of hydrogen on HO-1 expression in the brainafter focal cerebral ischemia reperfusion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results suggest that the neuroprotective effects of hydrogen may be mediated by promoting HO-1 expression and attenuated the oxidative injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats – A possible new hydrogen resource for clinical use.

This animal study examined Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats – A possible new hydrogen resource for clinical use. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Pathologically, tissues from rats in hydrogen inhalation group showed no significant difference compared with the control group in HE staining pictures. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhaling Hydrogen Ameliorates Early Postresuscitation EEG Characteristics in an Asphyxial Cardiac Arrest Rat Model

This uncontrolled human study examined Inhaling Hydrogen Ameliorates Early Postresuscitation EEG Characteristics in an Asphyxial Cardiac Arrest Rat Model. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Recent animal studies found that hydrogen inhalation after CA greatly improved neurological outcomes by selectively neutralizing highly reactive oxidants, but the effect of hydrogen…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of 2% Hydrogen Improves Survival Rate and Attenuates Shedding of Vascular Endothelial Glycocalyx in Rats with Heat Stroke.

This animal study examined Inhalation of 2% Hydrogen Improves Survival Rate and Attenuates Shedding of Vascular Endothelial Glycocalyx in Rats with Heat Stroke. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results showed that 2% hydrogen gas significantly improved survival in the heat-stroked rats and partially preserved the thickness of the endothelial glycocalyx. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen saline offers neuroprotection by reducing oxidative stress in a focal cerebral ischemia-reperfusion rat model

This animal study examined Hydrogen saline offers neuroprotection by reducing oxidative stress in a focal cerebral ischemia-reperfusion rat model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These findings demonstrated hydrogen saline is neuroprotective when administered within 6 h after ischemia. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas therapy improves survival rate and neurological deficits in subarachnoid hemorrhage rats: a pilot study.

This animal study examined Hydrogen gas therapy improves survival rate and neurological deficits in subarachnoid hemorrhage rats: a pilot study. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation; reported duration 2 hours. The abstract reports: Our results correlate well with the proposed mechanisms of hydrogen gas therapy within the literature. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas post‑conditioning attenuates early neuronal pyroptosis in a rat model of subarachnoid hemorrhage through the mitoKATP signaling pathway

This animal study examined Hydrogen gas post‑conditioning attenuates early neuronal pyroptosis in a rat model of subarachnoid hemorrhage through the mitoKATP signaling pathway. The abstract describes Rat model. The abstract reports: Therefore, these observations suggest that post-conditioning with hydrogen gas ameliorated SAH-induced neuronal pyroptosis at least in part through the mitoK/ERK1/2/p38 MAPK signaling pathway. This is an automated editorial draft based on the abstract and requires source review before publication.

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H 2 Gas Improves Functional Outcome After Cardiac Arrest to an Extent Comparable to Therapeutic Hypothermia in a Rat Model

This animal study examined H 2 Gas Improves Functional Outcome After Cardiac Arrest to an Extent Comparable to Therapeutic Hypothermia in a Rat Model. The abstract describes Rat model. The abstract reports: Inhalation of H(2) gas is a favorable strategy to mitigate mortality and functional outcome of post-CA syndrome in a rat model, either alone or…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas post-conditioning alleviates cognitive dysfunction and anxiety-like behavior in a rat model of subarachnoid hemorrhage.

This animal study examined Hydrogen gas post-conditioning alleviates cognitive dysfunction and anxiety-like behavior in a rat model of subarachnoid hemorrhage. The abstract describes Rat model; sample size 36. The abstract reports: Subarachnoid hemorrhage (SAH) results in high rates of mortality and lasting disability. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen‑rich saline promotes neuronal recovery in mice with cerebral ischemia through the AMPK/mTOR signal‑mediated autophagy pathway.

This animal study examined Hydrogen‑rich saline promotes neuronal recovery in mice with cerebral ischemia through the AMPK/mTOR signal‑mediated autophagy pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen therapy after resuscitation improves myocardial injury involving inhibition of autophagy in an asphyxial rat model of cardiac arrest

This animal study examined Hydrogen therapy after resuscitation improves myocardial injury involving inhibition of autophagy in an asphyxial rat model of cardiac arrest. The abstract describes Rat model. The abstract reports: The results showed that H therapy significantly improved post-resuscitation survival and cardiac function. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation inhibits microglia activation and neuroinflammation in a rat model of traumatic brain injury

This animal study examined Hydrogen inhalation inhibits microglia activation and neuroinflammation in a rat model of traumatic brain injury. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Recent studies have demonstrated the potential neuroprotective effects of molecular hydrogen on TBI. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of a high concentration of hydrogen on neurological function after traumatic brain injury in diabetic rats.

This uncontrolled human study examined Effects of a high concentration of hydrogen on neurological function after traumatic brain injury in diabetic rats. The abstract describes Human participants. The abstract reports: We found that the inhalation of high concentrations of H significantly improved outcomes following TBI in diabetic rats. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of high-concentration hydrogen gas attenuates cognitive deficits in a rat model of asphyxia induced-cardiac arrest

This animal study examined Inhalation of high-concentration hydrogen gas attenuates cognitive deficits in a rat model of asphyxia induced-cardiac arrest. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation; reported duration 1 hour. The abstract reports: Our findings suggest that water electrolysis derived 67% hydrogen gas may be an effective therapeutic approach for improving cognitive outcomes associated with global brain…. This is an automated editorial draft based on the abstract and requires source review before publication.

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