Protective effect of hydrogen-rich water on spermatogenesis in high-fat diet obese rats.

This animal study examined Protective effect of hydrogen-rich water on spermatogenesis in high-fat diet obese rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that the HFD significantly increased food intake, body weight, and lee index, all of which were reduced in the HRW-treated obese…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Treatment with hydrogen-rich water protects against thioacetamide-induced hepatic encephalopathy in rats through stabilizing liver-brain disturbance.

This animal study examined Treatment with hydrogen-rich water protects against thioacetamide-induced hepatic encephalopathy in rats through stabilizing liver-brain disturbance. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: The results showed that hydrogen-rich water can improve the behavioral changes of the HE rats, reduce blood ammonia, reduce liver function damage, alleviate the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice.

This uncontrolled human study examined iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: The results of the H&E, and Nissl staining indicated that the CLP mice had a significant brain injury, which was characterized by aggravated pathological…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins.

This animal study examined Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Based on our results, HRW treatment was able to reduce brain infarct volume and improve neurological function following ischemic brain injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen rich saline reduces immune-mediated brain injury in rats with acute carbon monoxide poisoning.

This animal study examined Hydrogen rich saline reduces immune-mediated brain injury in rats with acute carbon monoxide poisoning. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: CO-exposed rats showed the increase in neuron loss and the decrease in antioxidant capacities. And H(2) rich saline given after CO poisoning can prevent…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats.

This animal study examined Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results indicated that hSCI significantly decreased the hind limb neurological function, testis index, MSTD, and MSET, and induced severe testicular morphological injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen is neuroprotective against surgically induced brain injury.

This controlled preclinical study evaluated whether inhaled molecular hydrogen reduced brain injury caused by a surgical procedure in adult male Sprague-Dawley rats. Animals underwent sham surgery, surgically induced brain injury without treatment, or surgically induced brain injury with 2.9% hydrogen inhaled concurrently during the 60-minute surgical procedure.

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Hydrogen exerts neuroprotective effects by inhibiting oxidative stress in experimental diabetic peripheral neuropathy rats.

This animal study examined Hydrogen exerts neuroprotective effects by inhibiting oxidative stress in experimental diabetic peripheral neuropathy rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation and hydrogen-rich saline. The abstract reports: Further studies showed that hydrogen significantly upregulated the expression of nuclear factor erythroid-2-related factor 2 and downstream proteins such as catalase and hemeoxygenase-1 in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen alleviates hypoxic-ischaemic brain damage in neonatal rats by inhibiting injury of brain pericytes.

This animal study examined Hydrogen alleviates hypoxic-ischaemic brain damage in neonatal rats by inhibiting injury of brain pericytes. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that HRW significantly attenuated HI-induced oxidative stress in the brain pericytes of neonatal rats, partly through the Nrf2-HO-1 pathway, further improving…. This is an automated editorial draft based on the abstract and requires source review before publication.

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DGKζ in Glycerophospholipid Metabolism Regulates the DAG and PA Balance and Interacts With PTEN to Alleviate Brain Damage in Septic Mice With Hydrogen Inhalation: A Comparative Metabolomic and Phosphoproteomic Analysis.

This narrative review examined DGKζ in Glycerophospholipid Metabolism Regulates the DAG and PA Balance and Interacts With PTEN to Alleviate Brain Damage in Septic Mice With Hydrogen Inhalation: A Comparative Metabolomic and Phosphoproteomic Analysis. The abstract describes Published literature review; hydrogen delivered as hydrogen inhalation. The abstract reports: The correlated differential phosphoproteins found in the combined metabolomic and phosphoproteomic analyses participated in 131 pathways, and the differentially abundant metabolites were involved in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Promotes the Effectiveness of Bone Mesenchymal Stem Cell Transplantation in Rats with Spinal Cord Injury.

This animal study examined Hydrogen Promotes the Effectiveness of Bone Mesenchymal Stem Cell Transplantation in Rats with Spinal Cord Injury. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats.

This animal study examined Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats. The abstract describes Rat model. The abstract reports: These findings suggest that H augments cellular antioxidant defense capacity through activation of MAPK signaling pathways, leading to HO-1 expression and subsequent upregulation of…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats.

This animal study examined Hydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results showed that hypoxia–ischemia injury induced the inflammatory response of microglia; however, these changes were inhibited by hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats.

This animal study examined Protective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: It has previously been demonstrated that hyperglycemia‑induced oxidative stress and inflammation are closely associated with the development of diabetic complications, including diabetic neuropathy. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy.

This uncontrolled human study examined Effects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These data demonstrated that HRS can improve survival rate, attenuate neuroinflammation, astrocyte and microglial activation, neuronal injury and mitochondrial dysfunction in juvenile SAE rat…. This is an automated editorial draft based on the abstract and requires source review before publication.

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