Hydrogen alleviated cognitive impairment and blood‒brain barrier damage in sepsis-associated encephalopathy by regulating ABC efflux transporters in a PPARα-dependent manner.
This animal study examined Hydrogen alleviated cognitive impairment and blood‒brain barrier damage in sepsis-associated encephalopathy by regulating ABC efflux transporters in a PPARα-dependent manner. The abstract describes Mouse model. The abstract reports: Finally, we found that H improved survival rates and brain dysfunction and decreased inflammatory cytokines. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen‐Rich Water Improves Cognitive Ability and Induces Antioxidative, Antiapoptotic, and Anti‐Inflammatory Effects in an Acute Ischemia‐Reperfusion Injury Mouse Model
This animal study examined Hydrogen‐Rich Water Improves Cognitive Ability and Induces Antioxidative, Antiapoptotic, and Anti‐Inflammatory Effects in an Acute Ischemia‐Reperfusion Injury Mouse Model. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen treatment could potentially be a future therapeutic strategy for ischemia and its derived neurodegenerative diseases by improving cognitive abilities and inducing antioxidative and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates sepsis-induced neuroinflammation and cognitive impairment through regulation of DNMT1 and DNMT3a-mediated BDNF promoter IV methylation in mice.
This uncontrolled human study examined Hydrogen gas alleviates sepsis-induced neuroinflammation and cognitive impairment through regulation of DNMT1 and DNMT3a-mediated BDNF promoter IV methylation in mice. The abstract describes Human participants. The abstract reports: We found that 2% H inhalation can reduce pro-inflammatory factors, alleviate DNMT1, DNMT3a but not DNMT3b expression, make hypomethylation of BDNF promoter IV at…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDifferent effects of hydrogen-rich water intake and hydrogen gas inhalation on gut microbiome and plasma metabolites of rats in health status.
This animal study examined Different effects of hydrogen-rich water intake and hydrogen gas inhalation on gut microbiome and plasma metabolites of rats in health status. The abstract describes Rat model; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: Pathway enrichment analysis showed that HRW intake mainly affected starch and sucrose metabolism, and DMs in HI group were mainly enriched in arginine biosynthesis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTherapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model.
This animal study examined Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation; reported duration 30 min. The abstract reports: Our results demonstrated that TMT exposure alters seizure and spatial recognition memory. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline reverses oxidative stress, cognitive impairment, and mortality in rats submitted to sepsis by cecal ligation and puncture.
This animal study examined Hydrogen-rich saline reverses oxidative stress, cognitive impairment, and mortality in rats submitted to sepsis by cecal ligation and puncture. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: These findings indicate that HRS could attenuate the consequences of sepsis induced by cecal ligation and puncture in rats, at least in part, by…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen ameliorates chronic intermittent hypoxia-induced neurocognitive impairment via inhibiting oxidative stress.
This uncontrolled human study examined Hydrogen ameliorates chronic intermittent hypoxia-induced neurocognitive impairment via inhibiting oxidative stress. The abstract describes Human participants; reported duration 5 weeks. The abstract reports: Our results showed that H treatment improved the CIH-induced spatial learning and memory impairments. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Ameliorates Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice Via the Nrf2-ARE Signaling Pathway.
This animal study examined Hydrogen-Rich Saline Ameliorates Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice Via the Nrf2-ARE Signaling Pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: We found that HRS reduced the severity of EAE in mice and alleviated inflammation and demyelination. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen as an Emerging Therapeutic Medical Gas for Neurodegenerative and Other Diseases
This animal study examined Molecular Hydrogen as an Emerging Therapeutic Medical Gas for Neurodegenerative and Other Diseases. The abstract describes hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of Molecular Hydrogen on Methamphetamine-Induced Neurotoxicity and Spatial Memory Impairment.
This animal study examined Effects of Molecular Hydrogen on Methamphetamine-Induced Neurotoxicity and Spatial Memory Impairment. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: We found that the molecular hydrogen delivered by HRW consumption significantly inhibited the METH-induced spatial learning impairment and memory loss evidenced in the Barnes…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen inhalation attenuates postoperative cognitive impairment in rats.
This animal study examined Molecular hydrogen inhalation attenuates postoperative cognitive impairment in rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Many studies have found that molecular hydrogen (H2) has significant neuroprotection against acute and chronic neurological injury by regulating inflammation and apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDrinking hydrogen water ameliorated cognitive impairment in senescence-accelerated mice.
This in vitro or cellular study examined Drinking hydrogen water ameliorated cognitive impairment in senescence-accelerated mice. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water; reported duration 30 days. The abstract reports: On the basis of our results, hydrogen water merits further investigation for possible therapeutic/preventative use for age-related cognitive disorders. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Effectively Heals Alkali-Injured Cornea via Suppression of Oxidative Stress.
This animal study examined Molecular Hydrogen Effectively Heals Alkali-Injured Cornea via Suppression of Oxidative Stress. The abstract describes Rabbit model. The abstract reports: Results show that irrigation of the damaged eyes with H solution immediately after the injury and then within next five days renewed corneal transparency…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment
This randomized controlled trial examined Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment. The abstract describes Human participants; sample size 73. The abstract reports: H2-water may have a potential for suppressing dementia in an oxidative stress model and in the APOE4 carriers with MCI. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreFoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia.
This animal study examined FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Autophagy, a self-cannibalization mechanism, has been demonstrated to be involved in VD progression. This is an automated editorial draft based on the abstract and requires source review before publication.
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