The protective effects of hydrogen on HO-1 expression in the brainafter focal cerebral ischemia reperfusion in rats.
This animal study examined The protective effects of hydrogen on HO-1 expression in the brainafter focal cerebral ischemia reperfusion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results suggest that the neuroprotective effects of hydrogen may be mediated by promoting HO-1 expression and attenuated the oxidative injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas treatment prolongs replicative lifespan of bone marrow multipotential stromal cells in vitro while preserving differentiation and paracrine potentials.
This animal study examined Hydrogen gas treatment prolongs replicative lifespan of bone marrow multipotential stromal cells in vitro while preserving differentiation and paracrine potentials. The abstract describes Animal model. The abstract reports: Interestingly, 3% hydrogen gas treatment did not decrease hydroxyl radical, protein carbonyl, and 8-hydroxydeoxyguanosine, suggesting that scavenging hydroxyl radical might not be responsible for…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen mitigates traumatic brain injury-induced lung injury via NLRP3 inflammasome inhibition.
This animal study examined Molecular hydrogen mitigates traumatic brain injury-induced lung injury via NLRP3 inflammasome inhibition. The abstract describes Mouse model. The abstract reports: 2% H can protect against TBI-induced lung injury by inhibiting NLRP3 inflammasome activation, thereby alleviating inflammation and inhibiting apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMagnesium silicate nanosheets enable sustained hydrogen release to attenuate secondary brain injury following intracerebral hemorrhage.
This animal study examined Magnesium silicate nanosheets enable sustained hydrogen release to attenuate secondary brain injury following intracerebral hemorrhage. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: RESULTS: MGNs exhibited a two-dimensional structure and enabled sustained hydrogen release, particularly under acidic conditions. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats – A possible new hydrogen resource for clinical use.
This animal study examined Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats – A possible new hydrogen resource for clinical use. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Pathologically, tissues from rats in hydrogen inhalation group showed no significant difference compared with the control group in HE staining pictures. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhaling Hydrogen Ameliorates Early Postresuscitation EEG Characteristics in an Asphyxial Cardiac Arrest Rat Model
This uncontrolled human study examined Inhaling Hydrogen Ameliorates Early Postresuscitation EEG Characteristics in an Asphyxial Cardiac Arrest Rat Model. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Recent animal studies found that hydrogen inhalation after CA greatly improved neurological outcomes by selectively neutralizing highly reactive oxidants, but the effect of hydrogen…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of 2% Hydrogen Improves Survival Rate and Attenuates Shedding of Vascular Endothelial Glycocalyx in Rats with Heat Stroke.
This animal study examined Inhalation of 2% Hydrogen Improves Survival Rate and Attenuates Shedding of Vascular Endothelial Glycocalyx in Rats with Heat Stroke. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results showed that 2% hydrogen gas significantly improved survival in the heat-stroked rats and partially preserved the thickness of the endothelial glycocalyx. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen saline offers neuroprotection by reducing oxidative stress in a focal cerebral ischemia-reperfusion rat model
This animal study examined Hydrogen saline offers neuroprotection by reducing oxidative stress in a focal cerebral ischemia-reperfusion rat model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These findings demonstrated hydrogen saline is neuroprotective when administered within 6 h after ischemia. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Treatment Improves the Neurological Outcome After Traumatic Brain Injury Via Increasing miR-21 Expression.
This animal study examined Hydrogen Gas Treatment Improves the Neurological Outcome After Traumatic Brain Injury Via Increasing miR-21 Expression. The abstract describes Rat model. The abstract reports: Here, we found that H2 treatment significantly increased the expression of miR-21 in brain from 6 h to 3 d after TBI. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas therapy improves survival rate and neurological deficits in subarachnoid hemorrhage rats: a pilot study.
This animal study examined Hydrogen gas therapy improves survival rate and neurological deficits in subarachnoid hemorrhage rats: a pilot study. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation; reported duration 2 hours. The abstract reports: Our results correlate well with the proposed mechanisms of hydrogen gas therapy within the literature. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas post‑conditioning attenuates early neuronal pyroptosis in a rat model of subarachnoid hemorrhage through the mitoKATP signaling pathway
This animal study examined Hydrogen gas post‑conditioning attenuates early neuronal pyroptosis in a rat model of subarachnoid hemorrhage through the mitoKATP signaling pathway. The abstract describes Rat model. The abstract reports: Therefore, these observations suggest that post-conditioning with hydrogen gas ameliorated SAH-induced neuronal pyroptosis at least in part through the mitoK/ERK1/2/p38 MAPK signaling pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreH 2 Gas Improves Functional Outcome After Cardiac Arrest to an Extent Comparable to Therapeutic Hypothermia in a Rat Model
This animal study examined H 2 Gas Improves Functional Outcome After Cardiac Arrest to an Extent Comparable to Therapeutic Hypothermia in a Rat Model. The abstract describes Rat model. The abstract reports: Inhalation of H(2) gas is a favorable strategy to mitigate mortality and functional outcome of post-CA syndrome in a rat model, either alone or…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas post-conditioning alleviates cognitive dysfunction and anxiety-like behavior in a rat model of subarachnoid hemorrhage.
This animal study examined Hydrogen gas post-conditioning alleviates cognitive dysfunction and anxiety-like behavior in a rat model of subarachnoid hemorrhage. The abstract describes Rat model; sample size 36. The abstract reports: Subarachnoid hemorrhage (SAH) results in high rates of mortality and lasting disability. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreGender-based differences in neuroprotective effects of hydrogen gas against intracerebral hemorrhage-induced depression.
This uncontrolled human study examined Gender-based differences in neuroprotective effects of hydrogen gas against intracerebral hemorrhage-induced depression. The abstract describes Human participants; reported duration 3 days. The abstract reports: Estrogen was responsible for increased H sensitivity in male mice with ICH. The underlying mechanism may be associated with the suppression of NF-κB signaling…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen‑rich saline promotes neuronal recovery in mice with cerebral ischemia through the AMPK/mTOR signal‑mediated autophagy pathway.
This animal study examined Hydrogen‑rich saline promotes neuronal recovery in mice with cerebral ischemia through the AMPK/mTOR signal‑mediated autophagy pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. This is an automated editorial draft based on the abstract and requires source review before publication.
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