Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes.

HW-bathing significantly improved wrinkle in four subjects on the back of neck on 90th day as compared to 0 day. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to determine clinical relevance.

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Electrolysed-reduced water dialysate improves T-cell damage in end-stage renal disease patients with chronic haemodialysis.

In 42 patients with ERW for 1 year, the intracellular IL-2 and IFN-gamma levels in the Th1/Tc1 cells significantly increased and the intracellular IL-4, IL-6 and IL-10 levels in the Th2/Tc2 cells decreased.

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Effectiveness and safety of hydrogen inhalation as an adjunct treatment in Chinese type 2 diabetes patients: A retrospective, observational, double-arm, real-life clinical study.

Patients in hydrogen-inhalation group was observed a lower incidence of several AEs including hypoglycemia (2.0% vs 6.8%), vomiting (2.6% vs 7.4%), constipation (1.7% vs 4.4%) and giddiness (3.3% vs 6.3%) with significance in comparison to the control group.

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The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction – First Pilot Study in Humans.

In this pilot study, hydrogen inhalation during percutaneous coronary intervention was feasible and safe and may have promoted favorable left-ventricular remodeling six months after STEMI. This small, open-label, pilot study suggests therapeutic potential, while larger randomized, placebo-controlled studies are needed to confirm the finding.

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A Gallbladder Carcinoma Patient With Pseudo-Progressive Remission After Hydrogen Inhalation.

In this case report, tumors initially enlarged and tumor markers rose after hydrogen inhalation, followed by continued remission resembling pseudo-progression after anti-PD-1 therapy.

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