Intraperitoneally administered, hydrogen-rich physiologic solution protects against postoperative ileus and is associated with reduced nitric oxide production

This animal study examined Intraperitoneally administered, hydrogen-rich physiologic solution protects against postoperative ileus and is associated with reduced nitric oxide production. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: A single intraperitoneal dose of hydrogen-rich saline ameliorates postoperative ileus by inhibiting the inflammatory response and suppressing nitric oxide production. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen-rich saline on necrotizing enterocolitis in neonatal rats.

This animal study examined Protective effects of hydrogen-rich saline on necrotizing enterocolitis in neonatal rats. The abstract describes Rat model; sample size 11; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS showed beneficial effects on neonatal rats with NEC via decreasing oxidative stress, increasing antioxidant capacity, suppressing inflammation, and preserving mucosal integrity. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression.

This animal study examined Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: The histological study demonstrated milder inflammation in the DSS + HRW group, which was similar to normal inflammatory levels, and the macroscopic and microcosmic…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Comparative Efficiency of Intraperitoneal and Intravitreous Injection of Hydrogen Rich Saline against -Methyl–Nitrosourea Induced Retinal Degeneration: A Topographic Study.

This animal study examined The Comparative Efficiency of Intraperitoneal and Intravitreous Injection of Hydrogen Rich Saline against -Methyl–Nitrosourea Induced Retinal Degeneration: A Topographic Study. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Particularly, the topographic measurements suggested that the IV delivery of HRS could alleviate MNU induced photoreceptor degeneration in the posterior retina. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline reduces cell death through inhibition of DNA oxidative stress and overactivation of poly (ADP-ribose) polymerase-1 in retinal ischemia-reperfusion injury.

This animal study examined Hydrogen-rich saline reduces cell death through inhibition of DNA oxidative stress and overactivation of poly (ADP-ribose) polymerase-1 in retinal ischemia-reperfusion injury. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Overactivation of poly (ADP-ribose) polymerase 1 (PARP-1), as a result of sustained DNA oxidation in ischemia-reperfusion injury, triggers programmed cell necrosis and apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Acute Supplementation with Molecular Hydrogen Benefits Submaximal Exercise Indices. Randomized, Double-Blinded, Placebo-Controlled Crossover Pilot Study.

This randomized controlled trial examined Acute Supplementation with Molecular Hydrogen Benefits Submaximal Exercise Indices. Randomized, Double-Blinded, Placebo-Controlled Crossover Pilot Study. The abstract describes Human participants; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen as an Adjuvant Therapy May be Associated with Increased Oxygen Saturation and Improved Exercise Tolerance In a COVID-19 patient

This case report or case series examined Molecular Hydrogen as an Adjuvant Therapy May be Associated with Increased Oxygen Saturation and Improved Exercise Tolerance In a COVID-19 patient. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: This case report suggests that hydrogen-rich water (HRW) increases oxygen saturation increase exercise tolerance in a patient with COVID-19-like symptoms. This is an automated editorial draft based on the abstract and requires source review before publication.

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Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance.

This randomized controlled trial examined Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. The abstract describes Human participants; sample size 30; hydrogen delivered as hydrogen water; reported duration 8 weeks. The abstract reports: In conclusion, these results suggest that supplementation with hydrogen-rich water may have a beneficial role in prevention of T2DM and insulin resistance. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen-rich saline against erectile dysfunction in a streptozotocin induced diabetic rat model.

This animal study examined Protective effects of hydrogen-rich saline against erectile dysfunction in a streptozotocin induced diabetic rat model. The abstract describes Rat model; sample size 8; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 8 weeks. The abstract reports: Hydrogen-rich saline effectively improved erectile function in a streptozotocin induced diabetic rat model of erectile dysfunction. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen water reduces NSE, IL-6, and TNF-α levels in hypoxic-ischemic encephalopathy.

This in vitro or cellular study examined Hydrogen water reduces NSE, IL-6, and TNF-α levels in hypoxic-ischemic encephalopathy. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water; reported duration 10 days. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protein chip and bioinformatic analyses of differentially expressed proteins involved in the effect of hydrogen-rich water on myocardial ischemia-reperfusion injury.

This animal study examined Protein chip and bioinformatic analyses of differentially expressed proteins involved in the effect of hydrogen-rich water on myocardial ischemia-reperfusion injury. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas protects against serum and glucose deprivation‑induced myocardial injury in H9c2 cells through activation of the NF‑E2‑related factor 2/heme oxygenase 1 signaling pathway.

This animal study examined Hydrogen gas protects against serum and glucose deprivation‑induced myocardial injury in H9c2 cells through activation of the NF‑E2‑related factor 2/heme oxygenase 1 signaling pathway. The abstract describes Rat model. The abstract reports: Exposure of the cells to SGD also resulted in significant increases in HO‑1 expression and nuclear Nrf2 levels, and the HO‑1 inhibitor ZnPP IX and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats.

This animal study examined Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen potentiates beneficial anti-infarct effect of hypoxic postconditioning in isolated rat hearts: a novel cardioprotective intervention

This animal study examined Molecular hydrogen potentiates beneficial anti-infarct effect of hypoxic postconditioning in isolated rat hearts: a novel cardioprotective intervention. The abstract describes Rat model. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction - First Pilot Study in Humans.

This uncontrolled human study examined The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction - First Pilot Study in Humans. The abstract describes Human participants; sample size 20; hydrogen delivered as hydrogen inhalation; reported duration 6 month. The abstract reports: The first clinical study has shown that HI during PCI is feasible and safe and may also promote LV reverse remodeling at 6 months…. This is an automated editorial draft based on the abstract and requires source review before publication.

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