Hydrogen suppresses oxidative stress by inhibiting the p38 MAPK signaling pathway in preeclampsia.
This animal study examined Hydrogen suppresses oxidative stress by inhibiting the p38 MAPK signaling pathway in preeclampsia. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: It was found that hydrogen-rich saline (LH group) decreased placental MDA, proteinuria, TNF-α, and IL-1β levels in the placental tissues compared with the L…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreElectrochemically reduced water exerts superior reactive oxygen species scavenging activity in HT1080 cells than the equivalent level of hydrogen-dissolved water
This in vitro or cellular study examined Electrochemically reduced water exerts superior reactive oxygen species scavenging activity in HT1080 cells than the equivalent level of hydrogen-dissolved water. The abstract describes HT1080 cell model. The abstract reports: ERW has reactive oxygen species (ROS)-scavenging activity and recent studies demonstrated that hydrogen-dissolved water exhibits ROS-scavenging activity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis.
This animal study examined Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis. The abstract describes Rabbit model; hydrogen delivered as injected or infused hydrogen. The abstract reports: These results suggested that molecular hydrogen prevents steroid-induced osteonecrosis in rabbits by suppressing oxidative injury, vascular injury and apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Water and Lactulose Protect Against Growth Suppression and Oxidative Stress in Female Piglets Fed Toxins Contaminated Diets.
This animal study examined Hydrogen-Rich Water and Lactulose Protect Against Growth Suppression and Oxidative Stress in Female Piglets Fed Toxins Contaminated Diets. The abstract describes Porcine model; hydrogen delivered as hydrogen water; reported duration 25 days. The abstract reports: Results showed that both HRW and LAC treatments significantly attenuated the reduction of average daily gain (ADG) and average daily feed intake (ADFI) caused…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuated neuropathic pain by reducing oxidative stress.
This animal study examined Hydrogen-rich saline attenuated neuropathic pain by reducing oxidative stress. The abstract describes Rat model; sample size 10; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Intrathecal injection of hydrogen-rich saline can decrease oxidative stress and the expression of p38MAPK and BDNF that may contribute to the elevated threshold of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis.
This in vitro or cellular study examined Molecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen suppresses free-radical-induced cell death by mitigating fatty acid peroxidation and mitochondrial dysfunction.
This in vitro or cellular study examined Molecular hydrogen suppresses free-radical-induced cell death by mitigating fatty acid peroxidation and mitochondrial dysfunction. The abstract describes Cell culture / in vitro model. The abstract reports: As a result, H protected the cultured cells against the cytotoxic effects induced by -butyl hydroperoxide; H suppressed cellular fatty acid peroxidation and cell…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases.
Mitochondria are the major source of oxidative stress. Acute oxidative stress causes serious damage to tissues, and persistent oxidative stress is one of the causes of many common diseases, cancer and the aging process; however, there has been little success in developing an effective antioxidant with no side effect. We have reported that molecular hydrogen has potential as an effective antioxidant for medical applications [Ohsawa et al., Nat.
Read MoreHydrogen gas inhalation therapy may not work sufficiently to mitigate oxidative stress induced with REBOA
This animal study examined Hydrogen gas inhalation therapy may not work sufficiently to mitigate oxidative stress induced with REBOA. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation; reported duration 180 minutes. The abstract reports: Survival analysis showed no significant differences between the two groups (control vs. hydrogen, 4/5 vs. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhaled hydrogen gas therapy for prevention of noise-induced hearing loss through reducing reactive oxygen species.
This animal study examined Inhaled hydrogen gas therapy for prevention of noise-induced hearing loss through reducing reactive oxygen species. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation. The abstract reports: All animals underwent measurements for auditory brainstem response after the noise exposure; the results revealed that there was a better improvement in the threshold…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway.
This animal study examined Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway. The abstract describes Mouse model. The abstract reports: These results suggest that the LKB1-AMPK-FoxO1 signaling pathway is a critical mediator of the antioxidant properties of H, further supporting the idea that H…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates oxygen toxicity by reducing hydroxyl radical levels in PC12 cells.
This in vitro or cellular study examined Hydrogen gas alleviates oxygen toxicity by reducing hydroxyl radical levels in PC12 cells. The abstract describes PC12 cell model. The abstract reports: The data showed that H2 promoted the cell viability and inhibited the damage in the cell and mitochondria membrane, reduced the levels of lipid…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Water Attenuates Diarrhea in Weaned Piglets via Oxidative Stress Alleviation.
This animal study examined Hydrogen-Rich Water Attenuates Diarrhea in Weaned Piglets via Oxidative Stress Alleviation. The abstract describes Porcine model; hydrogen delivered as hydrogen water. The abstract reports: The results demonstrate that HRW significantly increased the average daily feed intake and significantly reduced the diarrhea rate in weaned piglets. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water induces aluminum tolerance in maize seedlings by enhancing antioxidant capacities and nutrient homeostasis.
This animal study examined Hydrogen-rich water induces aluminum tolerance in maize seedlings by enhancing antioxidant capacities and nutrient homeostasis. The abstract describes Animal model; hydrogen delivered as hydrogen water. The abstract reports: Our results demonstrated that Al stress triggered damage to the photosynthetic apparatus, plant growth inhibition, and reactive oxygen species (ROS) production, and boosted lipid…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAntioxidant Activity of Hydrogen Nanobubbles in Water with Different Reactive Oxygen Species both in Vivo and in Vitro.
Hydrogen water as a new therapeutic antioxidant has been widely used in living organisms under stress. In this study, we applied nanobubble (NB) technology to hydrogen water. The antioxidant capacity of hydrogen NB water was studied with respect to different reactive oxygen species (ROS) both in vitro and in vivo.
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