Hydrogen molecules (H2) improve perfusion recovery via antioxidant effects in experimental peripheral arterial disease.
This uncontrolled human study examined Hydrogen molecules (H2) improve perfusion recovery via antioxidant effects in experimental peripheral arterial disease. The abstract describes Human participants. The abstract reports: Laser Doppler perfusion imaging demonstrated that H2‑saturated water improved perfusion recovery, decreased the rate of necrosis, increased the capillary density in the gastrocnemius muscle…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen regulates PTEN‐AKT‐mTOR signaling via ROS to alleviate peritoneal dialysis‐related peritoneal fibrosis
This uncontrolled human study examined Molecular hydrogen regulates PTEN‐AKT‐mTOR signaling via ROS to alleviate peritoneal dialysis‐related peritoneal fibrosis. The abstract describes Human participants; hydrogen delivered as injected or infused hydrogen. The abstract reports: Furthermore, it has been found that molecular hydrogen alleviate fibrosis by eliminating intracellular ROS and inhibiting the activation of the PTEN/AKT/mTOR pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Accelerates Diabetic Wound Healing in Vivo and Its Interaction with the Renin-Angiotensin System Pathway.
This animal study examined Hydrogen-Rich Saline Accelerates Diabetic Wound Healing in Vivo and Its Interaction with the Renin-Angiotensin System Pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: This study confirmed that HRS promotes diabetic wound healing by alleviating oxidative stress and inflammation, and these effects may be mechanistically associated with the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe protective effect of hydrogen-rich water on rats with type 2 diabetes mellitus.
This uncontrolled human study examined The protective effect of hydrogen-rich water on rats with type 2 diabetes mellitus. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: The results showed that drinking HW suppressed the increase in glucose, total cholesterol, oxidative stress, and inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich water prepared by alternating-current-electrolysis on antioxidant activity, DNA oxidative injuries, and diabetes-related markers.
This study protocol examined Effects of hydrogen-rich water prepared by alternating-current-electrolysis on antioxidant activity, DNA oxidative injuries, and diabetes-related markers. The abstract describes Planned or registered research population; hydrogen delivered as hydrogen water; reported duration 10 minutes. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSubcutaneous injection of hydrogen gas is a novel effective treatment for type 2 diabetes.
This animal study examined Subcutaneous injection of hydrogen gas is a novel effective treatment for type 2 diabetes. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen; reported duration 4 weeks. The abstract reports: Subcutaneous injection of H significantly improves type 2 diabetes mellitus and diabetic nephropathy-related outcomes in a mouse model, supporting further consideration of subcutaneous injection…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich medium protects human skin fibroblasts from high glucose or mannitol induced oxidative damage.
This in vitro or cellular study examined Hydrogen-rich medium protects human skin fibroblasts from high glucose or mannitol induced oxidative damage. The abstract describes Fibroblast model. The abstract reports: The results revealed that both mannitol and high glucose could cause oxidative stress in HSFs. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Therapy Attenuates Inflammatory Pathway Signaling in Septic Mice.
This animal study examined Hydrogen Gas Therapy Attenuates Inflammatory Pathway Signaling in Septic Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: These findings may contribute to clarifying the mechanism of action of H therapy in sepsis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Nano-Bubble Water Suppresses ROS Generation, Adipogenesis, and Interleukin-6 Secretion in Hydrogen-Peroxide- or PMA-Stimulated Adipocytes and Three-Dimensional Subcutaneous Adipose Equivalents.
This in vitro or cellular study examined Hydrogen Nano-Bubble Water Suppresses ROS Generation, Adipogenesis, and Interleukin-6 Secretion in Hydrogen-Peroxide- or PMA-Stimulated Adipocytes and Three-Dimensional Subcutaneous Adipose Equivalents. The abstract describes HaCaT keratinocyte model. The abstract reports: Nanoparticle tracking analysis showed that fresh HW contains 1.17 × 10/mL of nano-sized hydrogen bubbles. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study.
This uncontrolled human study examined Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study. The abstract describes Human participants; sample size 20; hydrogen delivered as hydrogen water; reported duration 8 weeks. The abstract reports: The consumption of hydrogen rich water for 8 weeks resulted in a 39% increase (p. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water inhibits glucose and α,β -dicarbonyl compound-induced reactive oxygen species production in the SHR.Cg-Leprcp/NDmcr rat kidney.
This uncontrolled human study examined Hydrogen-rich water inhibits glucose and α,β -dicarbonyl compound-induced reactive oxygen species production in the SHR.Cg-Leprcp/NDmcr rat kidney. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: These results indicate that HRW inhibits the production of α,β-dicarbonyl compounds and ROS in the kidneys of SHR.Cg-Leprcp/NDmcr rats. Therefore, it has therapeutic potential…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects rat from oxygen glucose deprivation and reperusion-induced apoptosis through VDAC1 via Bcl-2.
This animal study examined Hydrogen-rich saline protects rat from oxygen glucose deprivation and reperusion-induced apoptosis through VDAC1 via Bcl-2. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS ameliorated OGD/RP-induced PC-12 cell apoptosis and provided a novel treatment option for ischemia. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome.
This uncontrolled human study examined Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome. The abstract describes Human participants; sample size 20; hydrogen delivered as hydrogen water; reported duration 10 weeks. The abstract reports: We have found that hydrogen (dihydrogen; H2) has beneficial lipid-lowering effects in high-fat diet-fed Syrian golden hamsters. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ.
This animal study examined Hydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The present study evaluated the effects of H2 on NAFLD in rats and concluded that H2‑rich saline had significant therapeutic effects on NAFLD induced…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreElectrolyzed hydrogen-rich water for oxidative stress suppression and improvement of insulin resistance: a multicenter prospective double-blind randomized control trial.
Electrolyzed hydrogen-rich water (EHW) is known to have suppressive effects on oxidative stress (OS). However, its benefit in type 2 diabetes mellitus (T2DM) remains unclear. This study aimed to investigate the effect of EHW on T2DM.
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