Effects of hydrogen as adjuvant treatment for unstable angina
This uncontrolled human study examined Effects of hydrogen as adjuvant treatment for unstable angina. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Clinical analysis showed hydrogen-rich water intake relieved angina symptoms in unstable angina patients. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConstitutive hydrogen inhalation prevents vascular remodeling via reduction of oxidative stress.
This animal study examined Constitutive hydrogen inhalation prevents vascular remodeling via reduction of oxidative stress. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation; reported duration 2 weeks. The abstract reports: Although the increase in superoxide anion production did not significantly differ between the hydrogen and control groups, DNA damage was decreased as a result…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.
This animal study examined Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA New Approach for the Prevention and Treatment of Cardiovascular Disorders. Molecular Hydrogen Significantly Reduces the Effects of Oxidative Stress.
This narrative review examined A New Approach for the Prevention and Treatment of Cardiovascular Disorders. Molecular Hydrogen Significantly Reduces the Effects of Oxidative Stress. The abstract describes Published literature review; hydrogen delivered as hydrogen water and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Redox dysregulation and a dyshomeostasis of inflammation arise from, and result in, cellular aberrations and pathological conditions, which lead to cardiovascular diseases. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreH2 inhibits TNF-α-induced lectin-like oxidized LDL receptor-1 expression by inhibiting nuclear factor κB activation in endothelial cells
H(2) is a therapeutic antioxidant that can reduce oxidative stress. Oxidized low-density lipoprotein, which plays roles in atherosclerosis, may promote endothelial dysfunction by binding the cell-surface receptor LOX-1. LOX-1 expression can be upregulated by various stimuli, including TNF-α.
Read MoreHydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model.
This animal study examined Hydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: HW intake may prevent lipid deposition in the rat aorta induced by periodontitis by decreasing serum ox-LDL levels and aortic oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Prevents Early Neurovascular Dysfunction Resulting from Inhibition of Oxidative Stress in STZ-Diabetic Rats
This animal study examined Hydrogen-Rich Saline Prevents Early Neurovascular Dysfunction Resulting from Inhibition of Oxidative Stress in STZ-Diabetic Rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Based on its inhibition of oxidative stress and up-regulation of anti-oxidative enzymes, we conclude that hydrogen-rich saline is a potentially valuable therapeutic modality for…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAttenuation of Cardiac Ischaemia-reperfusion Injury by Treatment with Hydrogen-rich Water.
This animal study examined Attenuation of Cardiac Ischaemia-reperfusion Injury by Treatment with Hydrogen-rich Water. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen-rich water may inhibit the apoptosis of cardiomyocytes after ischaemia-reperfusion by upregulating the expression of the JAK2-STAT3 signalling pathway, which reduces ischaemia-reperfusion injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-containing saline alleviates pressure overload-induced interstitial fibrosis and cardiac dysfunction in rats.
This animal study examined Hydrogen-containing saline alleviates pressure overload-induced interstitial fibrosis and cardiac dysfunction in rats. The abstract describes Rat model. The abstract reports: These results indicate that HCS treatment can improve cardiac function by reducing interstitial fibrosis in pressure‑overloaded rats through its anti‑oxidative properties and via suppression…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTreatment with hydrogen molecule attenuates cardiac dysfunction in streptozotocin-induced diabetic mice.
This uncontrolled human study examined Treatment with hydrogen molecule attenuates cardiac dysfunction in streptozotocin-induced diabetic mice. The abstract describes Human participants; sample size 83; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 5 days. The abstract reports: Treatment with hydrogen molecule attenuated cardiac dysfunction in streptozotocin-induced diabetic mice, which was independent of glycemic control. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas protects against serum and glucose deprivation‑induced myocardial injury in H9c2 cells through activation of the NF‑E2‑related factor 2/heme oxygenase 1 signaling pathway.
Ischemia or hypoxia‑induced myocardial injury is closely associated with oxidative stress. Scavenging free radicals and/or enhancing endogenous antioxidative defense systems may be beneficial for the impediment of myocardial ischemic injury. Hydrogen (H2) gas, as a water‑ and lipid‑soluble small molecule, is not only able to selectively eliminate hydroxyl (·OH) free radicals, but also to enhance endogenous antioxidative defense systems in rat lungs and arabidopsis plants.
Read MoreInhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats.
This animal study examined Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Attenuated N-methyl-N-Nitrosourea Induced Corneal Endothelial Injury by Upregulating Anti-Apoptotic Pathway.
This in vitro or cellular study examined Molecular Hydrogen Attenuated N-methyl-N-Nitrosourea Induced Corneal Endothelial Injury by Upregulating Anti-Apoptotic Pathway. The abstract describes Endothelial cell model; hydrogen delivered as hydrogen-rich saline; reported duration 14 days. The abstract reports: This study suggests that topical application of H2 could protect CECs against corneal damage factors through anti-apoptotic effect, reduce the incidence and severity of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBreathing nitric oxide plus hydrogen gas reduces ischemia-reperfusion injury and nitrotyrosine production in murine heart.
This animal study examined Breathing nitric oxide plus hydrogen gas reduces ischemia-reperfusion injury and nitrotyrosine production in murine heart. The abstract describes Mouse model; reported duration 60 min. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway.
This animal study examined Molecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway. The abstract describes Mouse model. The abstract reports: We found that molecular hydrogen (H2) exerts an anti-inflammatory effect. This is an automated editorial draft based on the abstract and requires source review before publication.
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