Atomic hydrogen surrounded by water molecules, H(H2O)m, modulates basal and UV-induced gene expressions in human skin in vivo.

This animal study examined Atomic hydrogen surrounded by water molecules, H(H2O)m, modulates basal and UV-induced gene expressions in human skin in vivo. The abstract describes Animal model. The abstract reports: We found that H(H2O)m prevented UV-induced ROS generation and inhibited UV-induced MMP-1, COX-2 and IL-6 expressions, and UV-induced JNK and c-Jun phosphorylation in HaCaT…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline attenuates skin ischemia/reperfusion induced apoptosis via regulating Bax/Bcl-2 ratio and ASK-1/JNK pathway.

This animal study examined Hydrogen-rich saline attenuates skin ischemia/reperfusion induced apoptosis via regulating Bax/Bcl-2 ratio and ASK-1/JNK pathway. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results indicate that hydrogen-rich saline could ameliorate ischemia/reperfusion injury and improve flap survival rate by inhibiting the apoptosis factor and, at the same…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of hydrogen-rich saline on ischemia/reperfusion injury in rat skin flap.

This animal study examined Protective effect of hydrogen-rich saline on ischemia/reperfusion injury in rat skin flap. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Our findings suggest that HRS mitigates I/R injury by decreasing inflammation and, therefore, has the potential for application as a therapy for improving skin…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Water Intake Accelerates Oral Palatal Wound Healing via Activation of the Nrf2/Antioxidant Defense Pathways in a Rat Model.

This animal study examined Hydrogen-Rich Water Intake Accelerates Oral Palatal Wound Healing via Activation of the Nrf2/Antioxidant Defense Pathways in a Rat Model. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results of this study support the hypothesis that oral administration of hydrogen-rich water benefits the wound healing process by decreasing oxidative stress and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts in culture or 3D-tissue equivalents, and wound-healing promotion, together with ROS-scavenging and relief from glutathione diminishment

This in vitro or cellular study examined Hydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts in culture or 3D-tissue equivalents, and wound-healing promotion, together with ROS-scavenging and relief from glutathione diminishment. The abstract describes Fibroblast model; hydrogen delivered as hydrogen water. The abstract reports: Extract from HW-treated HGF cells scavenged ROO· more markedly than that from DDW-treated cells, suggesting that HW can increase the intracellular antioxidant capacity. This is an automated editorial draft based on the abstract and requires source review before publication.

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Positive Effects of hydrogen water on 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice.

This animal study examined Positive Effects of hydrogen water on 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: In the present study, we investigated the effect of drinking hydrogen water (HW) on 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis in NC/Nga mice and found that…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Topically Applied Molecular Hydrogen Normalizes Skin Parameters Associated with Oxidative Stress: A Pilot Study.

This uncontrolled human study examined Topically Applied Molecular Hydrogen Normalizes Skin Parameters Associated with Oxidative Stress: A Pilot Study. The abstract describes Human participants; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: Although porphyrin levels showed a trend toward reduction, this change was not statistically significant. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen ameliorates psoriasis-like skin inflammation via inhibiting the cGAS–STING pathway

This animal study examined Hydrogen ameliorates psoriasis-like skin inflammation via inhibiting the cGAS–STING pathway | Clinical and Experimental Immunology | Oxford Academic. The abstract describes Mouse model; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: In a previous study, we demonstrated in a psoriasis mouse model that hydrogen-rich water, an effective reactive oxygen species (ROS) scavenger, significantly improves disease…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Progress in the Application of Molecular Hydrogen in Medical Skin Cosmetology.

Molecular hydrogen is a colorless, tasteless, biologically active small-molecule gas with reducing properties, demonstrating therapeutic and preventive effects across various human systems. Its mechanisms of action include selective antioxidation, anti-inflammatory effects, apoptosis inhibition, and the regulation of gene expression and signaling pathways. In the skin, molecular hydrogen reduces oxidative damage by scavenging free radicals and inhibiting oxidative stress, leading to improvements in texture and tone.

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Intermittent environmental exposure to hydrogen prevents skin photoaging through reduction of oxidative stress.

This animal study examined Intermittent environmental exposure to hydrogen prevents skin photoaging through reduction of oxidative stress. The abstract describes Mouse model. The abstract reports: Our findings support the notion that long-term, intermittent environmental exposure to hydrogen gas in daily life has a beneficial effect on UVA-induced photoaging. Geriatr…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect and mechanism of hydrogen‐rich bath on mice with imiquimod‐induced psoriasis

This animal study examined Effect and mechanism of hydrogen‐rich bath on mice with imiquimod‐induced psoriasis. The abstract describes Mouse model; hydrogen delivered as hydrogen water and hydrogen bath and topical hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Local Treatment of Hydrogen-Rich Saline Promotes Wound Healing In Vivo by Inhibiting Oxidative Stress via Nrf-2/HO-1 Pathway.

This animal study examined Local Treatment of Hydrogen-Rich Saline Promotes Wound Healing In Vivo by Inhibiting Oxidative Stress via Nrf-2/HO-1 Pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results showed that local treatment of hydrogen-rich saline shortened wound closure time and reduced the level of proinflammatory cytokines and lipid peroxidation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model.

This animal study examined Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 5 min. The abstract reports: Many studies have demonstrated the therapeutic effects of hydrogen in pathological conditions such as inflammation; however, little is known about its prophylactic effects. This is an automated editorial draft based on the abstract and requires source review before publication.

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Antioxidant Activity of Hydrogen Water Mask Pack Composed of Gel-Type Emulsion and Hydrogen Generation Powder.

This uncontrolled human study examined Antioxidant Activity of Hydrogen Water Mask Pack Composed of Gel-Type Emulsion and Hydrogen Generation Powder. The abstract describes Human participants; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline reduces tissue injury and improves skin flap survival on a rat hindlimb degloving injury model.

This animal study examined Hydrogen-rich saline reduces tissue injury and improves skin flap survival on a rat hindlimb degloving injury model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 5 days. The abstract reports: Repeated HRS injections after trauma increased the viability of skin flap in rat degloving injury model by decreasing local tissue injury, due to its…. This is an automated editorial draft based on the abstract and requires source review before publication.

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