Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined the available molecular-hydrogen literature. However, a clinical trial showed that inhaling a mixture of 1.2–1.4% molecular hydrogen–air increased urinary 8-hydroxy-2′-deoxyguanosine, a marker of oxidative stress, levels. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the…
Read ArticleHowever, dysplasia and the lower survival ratio were all improved by hydrogen in the LPS + H₂ group ( p < 0.01). This source-grounded publication contributes evidence relevant…
Read ArticleIn an animal model, particularly, hydrogen-rich water showed a promising reduction in these symptoms. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleIn female C57BL/6 mice, at the molecular level, HRW reduced spinal oxidative stress and ERK-dependent plasticity without altering spinal NLRP3 expression, whereas it fully reversed NLRP3 upregulation and…
Read ArticleIn mice, among these, Acaca, Fasn, and CD36 were decreased ( Figures 2G-I ), while Mttp and Apob were increased by high dose H₂ therapy ( Figures 2N,O…
Read ArticleIn mice, crystal deposition, tubular injury, fibrosis and increased ROS production in kidneys of mice induced by oxalate diet were improved with HRW administration. These preclinical findings add…
Read ArticleIn rats, however, hydrogen-rich saline treatment significantly increased the 24-h survival of rats to 53.33% (8 of 15 rats) in the HRS1 group and 86.67% (13 of 15…
Read ArticleIn a laboratory model, molecular hydrogen treatment promoted PKM2 lactylation without affecting total PKM2 expression. The authors concluded that molecular hydrogen can promote PKM2 lactylation to restrain NLRP3…
Read ArticleThe findings suggested that co-administration of hydrogen and metformin shows potent protective effects, as evidenced by increased survival rates, reduced fasting blood glucose, and decreased cell injury when…
Read ArticleIn rats, kEY FINDINGS: The myocardial infarct size, no-reflow area, cardiac function, microstructure and mitochondrial morphology of I/R model rats were significantly improved after hydrogen inhalation. These preclinical…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleWhen H₂ was pressurized into the medium for 2, 4, 6, 12, 24, 36, and 48 hours, the absorbance of medium containing H₂ at 450 nm was higher…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. In this review, evidence of the potential benefits of hydrogen molecules obtained from in vitro, in vivo, and clinical investigations…
Read ArticleIn mice, hydrogen pretreatment upregulated ROS and the expression of pyroptosis-related proteins, and increased the number of PI- and TUNEL-positive cells, as well as the release of LDH…
Read Article