Hydrogen protects lung from hypoxia/re-oxygenation injury by reducing hydroxyl radical production and inhibiting inflammatory responses.

This animal study examined Hydrogen protects lung from hypoxia/re-oxygenation injury by reducing hydroxyl radical production and inhibiting inflammatory responses. The abstract describes Mouse model. The abstract reports: We found that H/R-induced injury in our mouse model was associated with production of hydroxyl radicals as well as increased levels of colony-stimulating factors…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis.

This uncontrolled human study examined Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Recently, our and other studies have found that hydrogen gas (H₂) treatment can ameliorate the lung injury induced by sepsis, ventilator, hyperoxia, and ischemia-reperfusion. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen alleviates hyperoxic acute lung injury related endoplasmic reticulum stress in rats through upregulation of SIRT1.

This uncontrolled human study examined Hydrogen alleviates hyperoxic acute lung injury related endoplasmic reticulum stress in rats through upregulation of SIRT1. The abstract describes Human participants. The abstract reports: Our previous study found that: hydrogen could reduce HALI, as well as oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Protective effect of hydrogen-saturated saline on acute lung injury induced by oleic acid in rats.

This animal study examined Protective effect of hydrogen-saturated saline on acute lung injury induced by oleic acid in rats. The abstract describes Rat model. The abstract reports: HSS attenuated ALI induced by OA in rats and might protect against ALI through selective resistance to oxidation and inhibiting inflammatory infiltration. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hyperoxygenated Hydrogen-Rich Solution Suppresses Lung Injury Induced by Hemorrhagic Shock in Rats.

This animal study examined Hyperoxygenated Hydrogen-Rich Solution Suppresses Lung Injury Induced by Hemorrhagic Shock in Rats. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: These findings demonstrate that HOHS can protect the lung against ALI induced by hemorrhagic shock. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen-enriched water eliminates fine particles from the lungs and blood by enhancing phagocytic activity.

This animal study examined Hydrogen-enriched water eliminates fine particles from the lungs and blood by enhancing phagocytic activity. The abstract describes Mouse model; reported duration 10 weeks. The abstract reports: Collectively, the results indicate that HW not only effectively eliminated PM from the lungs and blood by enhancing phagocytic activity, but also attenuated the…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model

This animal study examined Hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model. The abstract describes Rat model; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: These results suggest that hydrogen inhalation slows the development of COPD-like lung disease in a cigarette smoke-induced rat model. Higher concentrations of hydrogen may…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice.

This uncontrolled human study examined Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice. The abstract describes Human participants; reported duration 8 weeks. The abstract reports: These results demonstrated that H-rich pure water attenuated CS-induced emphysema in SMP30-KO mice by reducing CS-induced oxidative DNA damage and premature cell senescence in…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Combination therapy with nitric oxide and molecular hydrogen in a murine model of acute lung injury.

This uncontrolled human study examined Combination therapy with nitric oxide and molecular hydrogen in a murine model of acute lung injury. The abstract describes Human participants. The abstract reports: Moreover, we have found that H2 inhalation can attenuate lung injury. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen ameliorates endotoxin-induced acute lung injury through AMPK-mediated bidirectional regulation of Caspase3.

This animal study examined Hydrogen ameliorates endotoxin-induced acute lung injury through AMPK-mediated bidirectional regulation of Caspase3. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. The abstract reports: The experimental results confirmed that hydrogen provided an essential solution to the dissipative effects of LPS on survival rate, weight loss and lung function. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Molecular Hydrogen in the Treatment of Respiratory Diseases.

This narrative review examined Molecular Hydrogen in the Treatment of Respiratory Diseases. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen alleviates cell damage and acute lung injury in sepsis via PINK1/Parkin-mediated mitophagy

This animal study examined Hydrogen alleviates cell damage and acute lung injury in sepsis via PINK1/Parkin-mediated mitophagy. The abstract describes Mouse model. The abstract reports: These results suggest that PINK1-mediated mitophagy plays a key role in the protective effects of hydrogen against cell injury in LPS-induced inflammation and CLP-induced…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner

This animal study examined High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Results showed that 66.7 % hydrogen alleviated lung pathological changes and pulmonary edema caused by LPS, and reduced the degree of ALI by inhibiting…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Protection by hydrogen against gamma ray-induced testicular damage in rats.

This animal study examined Protection by hydrogen against gamma ray-induced testicular damage in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results from this experimental study suggest that hydrogen has a possible protective effect against radiation-induced testicular damage. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Effects of vitamin C, vitamin E, and molecular hydrogen on the placental function in trophoblast cells.

This in vitro or cellular study examined Effects of vitamin C, vitamin E, and molecular hydrogen on the placental function in trophoblast cells. The abstract describes Cell culture / in vitro model. The abstract reports: Meanwhile hydrogen showed no such effects on cell proliferation and TNF-α expression, but it could affect the level of hCG, indicating hydrogen as a…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More