Hydrogen/oxygen therapy for the treatment of an acute exacerbation of chronic obstructive pulmonary disease: results of a multicenter, randomized, double-blind, parallel-group controlled trial
This registered clinical trial examined Hydrogen/oxygen therapy for the treatment of an acute exacerbation of chronic obstructive pulmonary disease: results of a multicenter, randomized, double-blind, parallel-group controlled trial. The abstract describes Planned or registered research population. The abstract reports: The trial demonstrated that hydrogen/oxygen therapy is superior to oxygen therapy in patient with AECOPD with acceptable safety and tolerability profile. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen ameliorates lung injury in a rat model of subacute exposure to concentrated ambient PM2.5 via Aryl hydrocarbon receptor.
This animal study examined Hydrogen ameliorates lung injury in a rat model of subacute exposure to concentrated ambient PM2.5 via Aryl hydrocarbon receptor. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: High concentrations of hydrogen could ameliorate pulmonary dysfunction, airway mucus hypersecretion, oxidation damage, and inflammation response in rats exposed to concentrated ambient PM2.5. Additionally,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice.
This animal study examined Hydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Molecular hydrogen exhibited a protective effect on the LIR-induced ALI model. Hydrogen decreased malondialdehyde and increased superoxide dismutase activity in lung tissues. Additionally, hydrogen…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAPOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis.
This animal study examined APOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis. The abstract describes Mouse model. The abstract reports: Animal experiments helped validate these results. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA narrative review of hydrogen therapy for COPD: aging-related insights.
This narrative review examined A narrative review of hydrogen therapy for COPD: aging-related insights. The abstract describes Published literature review. The abstract reports: H therapy shows consistent antioxidative, anti-inflammatory, and anti-senescence effects across preclinical and clinical settings, suggesting potential as an adjunctive treatment for COPD in aging…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA case of lung injury due to a hydrogen explosion caused by the simultaneous use of two home folk remedies devices.
This uncontrolled human study examined A case of lung injury due to a hydrogen explosion caused by the simultaneous use of two home folk remedies devices. The abstract describes Human participants. The abstract reports: Arterial blood gas analysis showed no deterioration, and computed tomography revealed no worsening of pulmonary findings or oxygen demand. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHigh Concentration Hydrogen Mitigates Sepsis-Induced Acute Lung Injury in Mice by Alleviating Mitochondrial Fission and Dysfunction.
This animal study examined High Concentration Hydrogen Mitigates Sepsis-Induced Acute Lung Injury in Mice by Alleviating Mitochondrial Fission and Dysfunction. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Lungs are among the organs that are affected in MOF, resulting in acute lung injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen is a promising therapeutic agent for pulmonary disease.
This narrative review examined Molecular hydrogen is a promising therapeutic agent for pulmonary disease. The abstract describes Published literature review. The abstract reports: Short- or long-term exposure to these harmful substances often results in lung injury, causing respiratory and lung diseases. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen alleviates asthma through inhibiting IL-33/ILC2 axis
This animal study examined Molecular hydrogen alleviates asthma through inhibiting IL-33/ILC2 axis. The abstract describes Mouse model. The abstract reports: These data demonstrated that H is efficient in suppressing allergen-induced asthma and could be developed as a therapeutics for asthma and other conditions of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe use of ultrapure molecular hydrogen enriched with atomic hydrogen in apparatuses of artificial lung ventilation in the fight against virus COVID-19.
This uncontrolled human study examined The use of ultrapure molecular hydrogen enriched with atomic hydrogen in apparatuses of artificial lung ventilation in the fight against virus COVID-19. The abstract describes Human participants; hydrogen delivered as oxyhydrogen. The abstract reports: Many studies have been carried out that have demonstrated that hydrogen has strong anti-inflammatory properties. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Attenuates Endotoxin-Induced Lung Injury by Activating Thioredoxin 1 and Decreasing Tissue Factor Expression.
This animal study examined Hydrogen Attenuates Endotoxin-Induced Lung Injury by Activating Thioredoxin 1 and Decreasing Tissue Factor Expression. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: LPS-stimulated THP-1 and HUVEC-C cells and showed that hydrogen decreases TF expression and MMP-9 activity, which were abolished by the Trx1 inhibitor, PX12. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of molecular hydrogen on lung injury from lung transplantation
This narrative review examined Protective effects of molecular hydrogen on lung injury from lung transplantation. The abstract describes Published literature review; hydrogen delivered as hydrogen water and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The reviewed studies showed that H improved the outcomes of lung transplantation by decreasing oxidative stress and inflammation at the donor and recipient phases. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of a hydrogen-rich solution during cold ischemia in rat lung transplantation.
This animal study examined Protective effects of a hydrogen-rich solution during cold ischemia in rat lung transplantation. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: The use of a hydrogen-rich preservation solution attenuates ischemia-reperfusion injury in rat lungs during cold ischemia through antioxidant and anti-inflammatory effects. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMaternal molecular hydrogen treatment attenuates lipopolysaccharide-induced rat fetal lung injury.
This animal study examined Maternal molecular hydrogen treatment attenuates lipopolysaccharide-induced rat fetal lung injury. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen is a potential protective agent in the management of acute lung injury.
This uncontrolled human study examined Molecular hydrogen is a potential protective agent in the management of acute lung injury. The abstract describes Human participants. The abstract reports: Several studies have demonstrated the preventive and therapeutic effects of molecular hydrogen in the various diseases. This is an automated editorial draft based on the abstract and requires source review before publication.
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