Effect of molecular hydrogen saturated alkaline electrolyzed water on disuse muscle atrophy in gastrocnemius muscle.
This animal study examined Effect of molecular hydrogen saturated alkaline electrolyzed water on disuse muscle atrophy in gastrocnemius muscle. The abstract describes Rat model; reported duration 3 weeks. The abstract reports: We showed that 8-OHdG, but not MDA, significantly increased by 149% and 145% in HU-NW and HU-AEW, respectively, when compared with CONT. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice.
This animal study examined Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice. The abstract describes Mouse model; reported duration 4 weeks. The abstract reports: Results of 16S rRNA gene sequencing analyses showed that the relative abundances of 20 taxa differed significantly in AEW-administered mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen suppresses gut inflammation and pyroptosis in ulcerative colitis through promoting PKM2 lactylation to block NLRP3 inflammasome activation.
This uncontrolled human study examined Molecular hydrogen suppresses gut inflammation and pyroptosis in ulcerative colitis through promoting PKM2 lactylation to block NLRP3 inflammasome activation. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Molecular hydrogen can promote PKM2 lactylation to restrain NLRP3 inflammasome-mediated pyroptosis and inflammation, thus ameliorating UC progression. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA preliminary therapeutic study of the effects of molecular hydrogen on intestinal dysbiosis and small intestinal injury in high-fat diet-loaded senescence-accelerated mice.
This animal study examined A preliminary therapeutic study of the effects of molecular hydrogen on intestinal dysbiosis and small intestinal injury in high-fat diet-loaded senescence-accelerated mice. The abstract describes Mouse model; sample size 10. The abstract reports: Our findings suggest that treatment with molecular hydrogen may affect microbiota profiling and suppress intestinal injury in HFD-loaded SAMP8. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen is comparable to sulfasalazine as a treatment for DSS-induced colitis in mice.
This animal study examined Molecular hydrogen is comparable to sulfasalazine as a treatment for DSS-induced colitis in mice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRecent advances in studies of molecular hydrogen in the treatment of pancreatitis.
This narrative review examined Recent advances in studies of molecular hydrogen in the treatment of pancreatitis. The abstract describes Published literature review. The abstract reports: Pancreatitis is an inflammatory disease of the pancreas characterized by acinar cell injury and is associated with the abnormal release of trypsin, which results…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen postconditioning promotes survival of rat retinal ganglion cells against ischemia/reperfusion injury through the PI3K/Akt pathway.
This animal study examined Hydrogen postconditioning promotes survival of rat retinal ganglion cells against ischemia/reperfusion injury through the PI3K/Akt pathway. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results showed that administration of HPC significantly inhibited the apoptosis of RGCs and protected the visual function. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
This animal study examined Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence. The abstract describes Mouse model. The abstract reports: Moreover, this result was consistent with the downregulation of expression of the oxidative stress hallmark OGG1. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAn Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress
This in vitro or cellular study examined An Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress. The abstract describes Epithelial cell model. The abstract reports: The results obtained with immunohistochemistry and pachymetry showed that in the corneas of H-pretreated eyes, slight oxidative stress appeared followed by an increased expression…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effect of molecular hydrogen against oxidative stress caused by peroxynitrite derived from nitric oxide in rat retina.
This animal study examined Protective effect of molecular hydrogen against oxidative stress caused by peroxynitrite derived from nitric oxide in rat retina. The abstract describes Rat model. The abstract reports: H2 reduces cellular peroxynitrite, a highly toxic reactive nitrogen species. Thus, H2 may be an effective and novel clinical tool for treating glaucoma and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury.
This animal study examined Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury. The abstract describes Rat model; reported duration 60 minutes. The abstract reports: H(2) has no known toxic effects on the human body. Thus, the results suggest that H(2)-loaded eye drops are a highly useful neuroprotective and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells.
This in vitro or cellular study examined Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells. The abstract describes Cell culture / in vitro model. The abstract reports: The results in the present study indicate that miR-9, miR-199 and miR-21 play an important role in the anti-inflammatory regulation of LPS-activated microglia cells…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe preventive and therapeutic effects of molecular hydrogen in ocular diseases and injuries where oxidative stress is involved
This narrative review examined The preventive and therapeutic effects of molecular hydrogen in ocular diseases and injuries where oxidative stress is involved. The abstract describes Published literature review. The abstract reports: In this review, we present the results of studies utilising H in the treatment of ocular diseases involving oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTherapeutic effect of molecular hydrogen in corneal UVB-induced oxidative stress and corneal photodamage.
This animal study examined Therapeutic effect of molecular hydrogen in corneal UVB-induced oxidative stress and corneal photodamage. The abstract describes Rabbit model. The abstract reports: We previously found that UVB irradiation of the cornea caused the imbalance between the antioxidant and prooxidant enzymes in the corneal epithelium, followed by…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of molecular hydrogen, a novelly-established antioxidant, on the retinal degeneration of hereditary retinitis pigmentosa: an study.
This animal study examined Effect of molecular hydrogen, a novelly-established antioxidant, on the retinal degeneration of hereditary retinitis pigmentosa: an study. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The ERG amplitude in mice from the control and H intervention groups showed no statistical differences ( 0.05). This is an automated editorial draft based on the abstract and requires source review before publication.
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