Hydrogen nanobubble water reduces cochlear inflammation and oxidative stress in noise-induced hearing loss via the gut-inner ear axis.
This animal study examined Hydrogen nanobubble water reduces cochlear inflammation and oxidative stress in noise-induced hearing loss via the gut-inner ear axis. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Increasing evidence suggests that environmental stress may disrupt gut microbial balance and promote inflammation that leads to distant organs, including cochlea. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen attenuated oxidized low-density lipoprotein-induced inflammation through the stimulation of autophagy via sirtuin 1.
This in vitro or cellular study examined Hydrogen attenuated oxidized low-density lipoprotein-induced inflammation through the stimulation of autophagy via sirtuin 1. The abstract describes Cell culture / in vitro model. The abstract reports: Hydrogen has been demonstrated to serve a protective role in diverse models of disease. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreExploring the Potential of H2 Therapy in Reducing Surgical Complications: A Review on Anti-inflammatory, Antioxidant, and Anti-fibrotic Mechanisms
This narrative review examined Exploring the Potential of H2 Therapy in Reducing Surgical Complications: A Review on Anti-inflammatory, Antioxidant, and Anti-fibrotic Mechanisms. The abstract describes Published literature review. The abstract reports: Hydrogen is demonstrated to attenuate the early inflammatory response by down-regulating proinflammatory cytokines alongside its anti-oxidative and anti-fibrotic effects. As a potential therapeutic agent…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreResearch Progress of Hydrogen on Chronic Nasal Inflammation.
This narrative review examined Research Progress of Hydrogen on Chronic Nasal Inflammation. The abstract describes Published literature review. The abstract reports: Therefore, anti-oxidative stress is a direction of research for the treatment of chronic nasal mucosal inflammatory diseases.Hydrogen, as a medically therapeutic gas, has been…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen as a novel regulator of cellular pyroptosis: mechanistic insights and therapeutic implications
This narrative review examined Molecular hydrogen as a novel regulator of cellular pyroptosis: mechanistic insights and therapeutic implications. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePotent anti-inflammatory responses: Role of hydrogen in IL-1α dominated early phase systemic inflammation.
This animal study examined Potent anti-inflammatory responses: Role of hydrogen in IL-1α dominated early phase systemic inflammation. The abstract describes Mouse model. The abstract reports: The results suggested that hydrogen is potentially inhibitive against inflammation by inhibiting HIF-1α and IL-1α release at early occurrence. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of molecular hydrogen on uterine inflammation during preterm labour.
This animal study examined Effect of molecular hydrogen on uterine inflammation during preterm labour. The abstract describes Mouse model. The abstract reports: Our previous studies demonstrated that molecular hydrogen (H), an anti-inflammatory agent, prevented inflammation-induced impairment in foetal brain and lung tissues in lipopolysaccharide (LPS)-induced rodent…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombating Oxidative Stress and Inflammation in COVID-19 by Molecular Hydrogen Therapy: Mechanisms and Perspectives.
This narrative review examined Combating Oxidative Stress and Inflammation in COVID-19 by Molecular Hydrogen Therapy: Mechanisms and Perspectives. The abstract describes Published literature review. The abstract reports: This situation results in impaired gas exchange, hypoxia, and other sequelae that lead to multisystem organ failure and death. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreH2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain.
This animal study examined H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain. The abstract describes Rat model. The abstract reports: We found that H2 clearly inhibited hyperalgesia and allodynia in neuropathic pain and also attenuated the pro-inflammatory cytokines TNF-α, IL-1β, and high-mobility group box…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreIn Situ Nanoreactor for Photosynthesizing H Gas To Mitigate Oxidative Stress in Tissue Inflammation.
This animal study examined In Situ Nanoreactor for Photosynthesizing H Gas To Mitigate Oxidative Stress in Tissue Inflammation. The abstract describes Mouse model. The abstract reports: Experimental results indicate that the Lip NR system that can photosynthesize H gas has great potential for mitigating oxidative stress in tissue inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen increases resilience to stress in mice.
This animal study examined Molecular hydrogen increases resilience to stress in mice. The abstract describes Mouse model; hydrogen delivered as oxyhydrogen. The abstract reports: The results showed that repeated inhalation of hydrogen-oxygen mixed gas [67%:33% (V/V)] significantly decreased both the acute and chronic stress-induced depressive- and anxiety-like behaviors…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators.
This in vitro or cellular study examined Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators. The abstract describes Cell culture / in vitro model. The abstract reports: We previously showed that H2 acts as a novel antioxidant to protect cells against oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model
This uncontrolled human study examined Combination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model. The abstract describes Human participants. The abstract reports: The results showed that the inhalation of H (2%) or hyperoxia (98%) alone improved the 14-day survival rate of ZY-challenged mice from 20 to…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreImpact of molecular hydrogen treatments on the innate immune activity and survival of zebrafish (Danio rerio) challenged with Aeromonas hydrophila.
This animal study examined Impact of molecular hydrogen treatments on the innate immune activity and survival of zebrafish (Danio rerio) challenged with Aeromonas hydrophila. The abstract describes Zebrafish model; hydrogen delivered as hydrogen water. The abstract reports: We have found an increased survival rate of bacteria-challenged zebrafish subjected to the HRW immersion treatment. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate.
This animal study examined Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
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