Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats.
This animal study examined Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats. The abstract describes Rat model. The abstract reports: The Si-based agent suppressed oxidative stress, apoptosis, and inflammatory reactions resulting from I/R injury, thereby contributing to improvements in skin flap survival. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe protective effects of molecular hydrogen in sepsis-associated encephalopathy: current status.
This uncontrolled human study examined The protective effects of molecular hydrogen in sepsis-associated encephalopathy: current status. The abstract describes Human participants. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen-mediated SIRT1 activation alleviates sepsis-associated encephalopathy by promoting mitophagy
This animal study examined Molecular hydrogen-mediated SIRT1 activation alleviates sepsis-associated encephalopathy by promoting mitophagy. The abstract describes Mouse model. The abstract reports: This study demonstrates that inhalation of 2% H2 exerts significant protective effects against SAE, in which SIRT1 plays a pivotal role by modulating PINK1-dependent…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen attenuates sepsis-induced neuroinflammation through regulation of microglia polarization through an mTOR-autophagy-dependent pathway.
This in vitro or cellular study examined Molecular hydrogen attenuates sepsis-induced neuroinflammation through regulation of microglia polarization through an mTOR-autophagy-dependent pathway. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen inhalation. The abstract reports: Sepsis-associated encephalopathy (SAE) is the cognitive impairment resulting from sepsis and is associated with increased morbidity and mortality. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAug 2019(mitochondrial dysfunction ,sepsis, autophagy)Hydrogen alleviates mitochondrial dysfunction and organ damage via autophagy-mediated NLRP3 inflammasome inactivation in sepsis
This animal study examined Aug 2019(mitochondrial dysfunction ,sepsis, autophagy)Hydrogen alleviates mitochondrial dysfunction and organ damage via autophagy-mediated NLRP3 inflammasome inactivation in sepsis. The abstract describes Mouse model. The abstract reports: The results demonstrated that LPS and ATP led to NLRP3 inflammasome pathway activation, excessive cytokine release, mitochondrial dysfunction and the activation of autophagy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA review of experimental studies of hydrogen as a new therapeutic agent in emergency and critical care medicine.
This narrative review examined A review of experimental studies of hydrogen as a new therapeutic agent in emergency and critical care medicine. The abstract describes Published literature review; hydrogen delivered as hydrogen water and hydrogen-rich saline and hydrogen bath and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Reverses Sepsis-induced Immunoparalysis: Insights from Longitudinal Deep Immunophenotyping.
This uncontrolled human study examined Molecular Hydrogen Reverses Sepsis-induced Immunoparalysis: Insights from Longitudinal Deep Immunophenotyping. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Although the patient ultimately succumbed to irreversible chronic comorbidities on day 86, this case of severe tricuspid regurgitation and Child-Pugh class B alcoholic cirrhosis…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen regulates mitochondrial quality to protect glial cells and alleviates sepsis-associated encephalopathy by Nrf2/YY1 complex promoting HO-1 expression.
This uncontrolled human study examined Hydrogen regulates mitochondrial quality to protect glial cells and alleviates sepsis-associated encephalopathy by Nrf2/YY1 complex promoting HO-1 expression. The abstract describes Human participants. The abstract reports: Hydrogen improved cell injury and mitochondrial quality, which were associated with HO-1 expression promoted by the Nrf2/YY1 complex in vitro. Thus, hydrogen treatment may…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota.
This uncontrolled human study examined Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota. The abstract describes Human participants; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: Molecular hydrogen treatment promotes functional outcomes after SAE in mice, which may be attributable to increasing beneficial bacteria, repressing harmful bacteria, and metabolic disorder,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRecent Advances in Studies of Molecular Hydrogen against Sepsis.
This narrative review examined Recent Advances in Studies of Molecular Hydrogen against Sepsis. The abstract describes Published literature review. The abstract reports: Molecular hydrogen is a new type of antioxidant with strong free radical scavenging ability, which has been demonstrated to be effective for treating various…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRhupus Syndrome With Multiple Drug Intolerances Managed by Reduced-dose Rituximab and Adjunctive Molecular Hydrogen Therapy: A Case Report
This case report or case series examined Rhupus Syndrome With Multiple Drug Intolerances Managed by Reduced-dose Rituximab and Adjunctive Molecular Hydrogen Therapy: A Case Report. The abstract describes Human participants. The abstract reports: This case suggests molecular hydrogen therapy as a potential adjuvant for refractory Rhupus with multiple drug intolerances, showing immune modulation, reduced inflammation, steroid withdrawal,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreH 2 inhalation therapy in patients with moderate COVID-19 (H 2 COVID): a prospective ascending-dose phase I clinical trial
This controlled human trial examined H 2 inhalation therapy in patients with moderate COVID-19 (H 2 COVID): a prospective ascending-dose phase I clinical trial. The abstract describes Human participants; sample size 12. The abstract reports: The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has triggered a serious global health crisis, resulting…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen‐rich and hyperoxygenate saline inhibits lipopolysaccharide‐induced lung injury through mediating NF‐κB/NLRP3 signaling pathway in C57BL/6 mice
This animal study examined Hydrogen‐rich and hyperoxygenate saline inhibits lipopolysaccharide‐induced lung injury through mediating NF‐κB/NLRP3 signaling pathway in C57BL/6 mice. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Hydrogen plays a more important role in the inflammatory and anti-apoptosis mechanisms, while oxygen improves hypoxia of the body, and thus, its molecular mechanism…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen(H2) treatment for acute erythymatous skin diseases. A report of 4 patients with safety data and a non-controlled feasibility study with H2 concentration measurement on two volunteers
This uncontrolled human study examined Hydrogen(H2) treatment for acute erythymatous skin diseases. A report of 4 patients with safety data and a non-controlled feasibility study with H2 concentration measurement on two volunteers. The abstract describes Human participants. The abstract reports: An improvement in acute erythemtous skin diseases followed the administration of H2 enriched fluid without compromising the safety. The H2 delivery study of two…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen: a therapeutic antioxidant and beyond.
This uncontrolled human study examined Molecular hydrogen: a therapeutic antioxidant and beyond. The abstract describes Human participants. The abstract reports: Emerging evidence has consistently demonstrated that molecular hydrogen is a promising therapeutic option for a variety of diseases and the underlying comprehensive mechanisms is…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBlog Categories
Recent Posts
October 21, 2020
November 16, 2020
October 02, 2017