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443 Articles

Early Aerobic Exercise Combined with Hydrogen-Rich Saline as Preconditioning Protects Myocardial Injury Induced by Acute Myocardial Infarction in Rats.

By H2HUBB Jul 22, 2026 0 Comments

In rats, the eAE-hydrogen-rich saline increased significantly left ventricular systolic pressure, reduced left ventricular end-diastolic pressure, and potentiated + dp/dtmax, -dp/dtmax, heart coefficient and pH after MI injury. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…

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Hydrogen gas treatment prolongs replicative lifespan of bone marrow multipotential stromal cells in vitro while preserving differentiation and paracrine potentials.

By H2HUBB Jul 22, 2026 0 Comments

In a laboratory model, interestingly, 3% hydrogen gas treatment did not decrease hydroxyl radical, protein carbonyl, and 8-hydroxydeoxyguanosine, suggesting that scavenging hydroxyl radical might not be responsible for…

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Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats – A possible new hydrogen resource for clinical use.

By H2HUBB Jul 22, 2026 0 Comments

This publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.

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Hydrogen gas therapy improves survival rate and neurological deficits in subarachnoid hemorrhage rats: a pilot study.

By H2HUBB Jul 22, 2026 0 Comments

In rats, hypothesized that hydrogen therapy would improve neurological function and increase survival rate in SAH. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…

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Hydrogen gas post-conditioning attenuates early neuronal pyroptosis in a rat model of subarachnoid hemorrhage through the mitoKATP signaling pathway.

By H2HUBB Jul 22, 2026 0 Comments

In rats, hydrogen gas reduced brain swelling, improved neurological function, and lowered markers of oxidative stress and neuronal pyroptosis after subarachnoid hemorrhage. These preclinical findings add evidence supporting…

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Effects of a high concentration of hydrogen on neurological function after traumatic brain injury in diabetic rats.

By H2HUBB Jul 22, 2026 0 Comments

In an animal model, the inhalation of 42% H₂ for one hour per day for 48 h significantly reduced brain edema, decreased the extravasation of sodium fluorescein, and…

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Hydrogen-rich saline ameliorates hippocampal neuron apoptosis through up-regulating the expression of cystathionine β-synthase (CBS) after cerebral ischemia- reperfusion in rats.

By H2HUBB Jul 22, 2026 0 Comments

In rats, hydrogen up-regulated H2S levels via promoting the expression of CBS in the hippocampus, and its treatment alleviated oxidative stress via activating the expression of Nrf2 and…

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Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway.

By H2HUBB Jul 22, 2026 0 Comments

In rats, hydrogen-rich water administration significantly increased 7-d survival rates, reduced neurologic deficits, and lowered intracellular oxidative stress levels. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…

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Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits.

By H2HUBB Jul 22, 2026 0 Comments

In contrast, the upregulated level of MDA, caspase-12/3 and brain edema was attenuated and the brain injury was substantially alleviated in the hydrogen treated rabbits, but the improvement…

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Hydrogen-rich saline injection into the subarachnoid cavity within 2 weeks promotes recovery after acute spinal cord injury.

By H2HUBB Jul 22, 2026 0 Comments

In rats, at 24 hours, 48 hours, 1 week and 2 weeks after injury showed that hydrogen-rich saline markedly reduced cell death, inflammatory cell infiltration, serum malondialdehyde content,…

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Hydrogen gas inhalation alleviates oxidative stress in patients with post-cardiac arrest syndrome.

By H2HUBB Jul 22, 2026 0 Comments

In 5 patients, oxidative stress was reduced and cytokine levels were unchanged in cardiogenic patients, whereas oxidative stress was unchanged and cytokine levels were diminished in the septic…

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Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model.

By H2HUBB Jul 22, 2026 0 Comments

In male Sprague-Dawley rats, hydrogen treatment significantly reduced the level of oxidative stress, neuroinflammation, neuronal damage, and apoptosis-related genes. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…

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Hydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage.

By H2HUBB Jul 22, 2026 0 Comments

In mice, the hydrogen inhalation reduced these effects acutely (24 h); however it exhibited only a tendency to improvement in the delayed study (72 h). These preclinical findings…

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Hydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats.

By H2HUBB Jul 22, 2026 0 Comments

In rats, HRW treatment improved neurological function and tended to improve overall survival but without significant difference. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…

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Inhalation of hydrogen gas attenuates cognitive impairment in transient cerebral ischemia via inhibition of oxidative stress.

By H2HUBB Jul 22, 2026 0 Comments

In male Wistar rats, the neuronal density 3·3±2·1 cells/mm in CA1 region of the ischemic rats increased to 21·7±2·6 cells/mm after they were treated with hydrogen gas. These…

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