DGKζ in Glycerophospholipid Metabolism Regulates the DAG and PA Balance and Interacts With PTEN to Alleviate Brain Damage in Septic Mice With Hydrogen Inhalation: A Comparative Metabolomic and Phosphoproteomic Analysis.
This narrative review examined DGKζ in Glycerophospholipid Metabolism Regulates the DAG and PA Balance and Interacts With PTEN to Alleviate Brain Damage in Septic Mice With Hydrogen Inhalation: A Comparative Metabolomic and Phosphoproteomic Analysis. The abstract describes Published literature review; hydrogen delivered as hydrogen inhalation. The abstract reports: The correlated differential phosphoproteins found in the combined metabolomic and phosphoproteomic analyses participated in 131 pathways, and the differentially abundant metabolites were involved in…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Promotes the Effectiveness of Bone Mesenchymal Stem Cell Transplantation in Rats with Spinal Cord Injury.
This animal study examined Hydrogen Promotes the Effectiveness of Bone Mesenchymal Stem Cell Transplantation in Rats with Spinal Cord Injury. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats.
This animal study examined Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats. The abstract describes Rat model. The abstract reports: These findings suggest that H augments cellular antioxidant defense capacity through activation of MAPK signaling pathways, leading to HO-1 expression and subsequent upregulation of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats.
This animal study examined Hydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results showed that hypoxia–ischemia injury induced the inflammatory response of microglia; however, these changes were inhibited by hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats.
This animal study examined Protective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: It has previously been demonstrated that hyperglycemia‑induced oxidative stress and inflammation are closely associated with the development of diabetic complications, including diabetic neuropathy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy.
This uncontrolled human study examined Effects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These data demonstrated that HRS can improve survival rate, attenuate neuroinflammation, astrocyte and microglial activation, neuronal injury and mitochondrial dysfunction in juvenile SAE rat…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMaternal molecular hydrogen administration on lipopolysaccharide-induced mouse fetal brain injury.
This animal study examined Maternal molecular hydrogen administration on lipopolysaccharide-induced mouse fetal brain injury. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Our results suggest that LPS-induced apoptosis, oxidative damage and inflammation in the fetal brain were ameliorated by maternal H2 administration. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePerioperatively Inhaled Hydrogen Gas Diminishes Neurologic Injury Following Experimental Circulatory Arrest in Swine.
This animal study examined Perioperatively Inhaled Hydrogen Gas Diminishes Neurologic Injury Following Experimental Circulatory Arrest in Swine. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation. The abstract reports: This study used a swine model of mildly hypothermic prolonged circulatory arrest and found that the addition of 2.4% inhaled hydrogen gas to inspiratory…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe neuroprotective effect of hyperoxygenate hydrogen-rich saline on CO-induced brain injury in rats.
This animal study examined The neuroprotective effect of hyperoxygenate hydrogen-rich saline on CO-induced brain injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Arterial oxygen partial pressure (PaO) and arterial oxygen saturation (SaO) results showed that HOS and HOHS could improve the oxygenation of the rats with…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water improves sleep consolidation and enhances forebrain neuronal activation in mice.
This animal study examined Hydrogen-rich water improves sleep consolidation and enhances forebrain neuronal activation in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 7 days. The abstract reports: HRW improves sleep consolidation and increases neuronal activation in sleep-related brain regions. It may serve as a simple, effective treatment to improve recovery after…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation exerts anti-seizure effects by preventing oxidative stress and inflammation in the hippocampus in a rat model of kainic acid-induced seizures
This animal study examined Hydrogen inhalation exerts anti-seizure effects by preventing oxidative stress and inflammation in the hippocampus in a rat model of kainic acid-induced seizures. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation; reported duration 5 days. The abstract reports: Hydrogen gas (H) is an antioxidant with demonstrated neuroprotective efficacy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePhosphorylation-mediated PI3K-Art signalling pathway as a therapeutic mechanism in the hydrogen-induced alleviation of brain injury in septic mice.
This animal study examined Phosphorylation-mediated PI3K-Art signalling pathway as a therapeutic mechanism in the hydrogen-induced alleviation of brain injury in septic mice. The abstract describes Mouse model. The abstract reports: In proteomics and phosphoproteomics analysis, 268 differentially phosphorylated proteins (DPPs) showed a change in the phosphorylated form in the CLP + H group (p . This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen‑rich medium alleviates high glucose‑induced oxidative stress and parthanatos in rat Schwann cells in vitro.
This animal study examined Hydrogen‑rich medium alleviates high glucose‑induced oxidative stress and parthanatos in rat Schwann cells in vitro. The abstract describes Rat model. The abstract reports: These results indicate that HM effectively reduces HG‑induced oxidative stress in RSCs and protects them against parthanatos. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Alleviates Sepsis-Induced Brain Injury by Improving Mitochondrial Biogenesis Through the Activation of PGC-α in Mice.
This uncontrolled human study examined Hydrogen Gas Alleviates Sepsis-Induced Brain Injury by Improving Mitochondrial Biogenesis Through the Activation of PGC-α in Mice. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: The present study showed that hydrogen gas therapy increased the 7-day survival rate, improved cognitive function, increased the mitochondrial function (MMP, ATP level, complex…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConsumption of Molecular Hydrogen Prevents the Stress-Induced Impairments in Hippocampus-Dependent Learning Tasks during Chronic Physical Restraint in Mice
This animal study examined Consumption of Molecular Hydrogen Prevents the Stress-Induced Impairments in Hippocampus-Dependent Learning Tasks during Chronic Physical Restraint in Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
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