Chronic hydrogen-rich saline treatment reduces oxidative stress and attenuates left ventricular hypertrophy in spontaneous hypertensive rats.

This uncontrolled human study examined Chronic hydrogen-rich saline treatment reduces oxidative stress and attenuates left ventricular hypertrophy in spontaneous hypertensive rats. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline; reported duration 3 months. The abstract reports: Recently, it has been demonstrated that hydrogen, as a novel antioxidant, can selectively reduce hydroxyl radicals and peroxynitrite anion to exert therapeutic antioxidant activity. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis.

This animal study examined Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis. The abstract describes Rabbit model; hydrogen delivered as injected or infused hydrogen. The abstract reports: These results suggested that molecular hydrogen prevents steroid-induced osteonecrosis in rabbits by suppressing oxidative injury, vascular injury and apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway.

This animal study examined Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway. The abstract describes Mouse model. The abstract reports: These results suggest that the LKB1-AMPK-FoxO1 signaling pathway is a critical mediator of the antioxidant properties of H, further supporting the idea that H…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect of Hydrogen-Rich Saline on Postoperative Intra-Abdominal Adhesion Bands Formation in Mice.

This animal study examined Effect of Hydrogen-Rich Saline on Postoperative Intra-Abdominal Adhesion Bands Formation in Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: RESULTS HRS did not affect PPAs formation on the 1st day, but did make a significant reduction on the 3rd and 7th days. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen-rich saline in preeclampsia rat model.

This animal study examined Protective effects of hydrogen-rich saline in preeclampsia rat model. The abstract describes Rat model; sample size 50; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: It was found that the pups of hypertensive gravid rats treated with hydrogen-rich saline presented fewer number of resorptions than those of the group…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich jelly attenuates adipose tissue inflammation and metabolic dysfunction in high-fat/high-sucrose diet-fed SAMP8 mice.

This in vitro or cellular study examined Hydrogen-rich jelly attenuates adipose tissue inflammation and metabolic dysfunction in high-fat/high-sucrose diet-fed SAMP8 mice. The abstract describes Cell culture / in vitro model. The abstract reports: These findings suggest that molecular hydrogen attenuates HFHSD-induced metabolic disturbances primarily through suppression of adipose inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Comparative study on protective effect of hydrogen rich saline and adipose-derived stem cells on hepatic ischemia-reperfusion and hepatectomy injury in swine.

This animal study examined Comparative study on protective effect of hydrogen rich saline and adipose-derived stem cells on hepatic ischemia-reperfusion and hepatectomy injury in swine. The abstract describes Porcine model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Our study has demonstrated that HRS and ADSCs have significant hepatoprotective effects in miniature pigs after HIRI and hepatectomy injury. However, liver parenchyma injection…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of hydrogen-rich water on spermatogenesis in high-fat diet obese rats.

This animal study examined Protective effect of hydrogen-rich water on spermatogenesis in high-fat diet obese rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that the HFD significantly increased food intake, body weight, and lee index, all of which were reduced in the HRW-treated obese…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Treatment with hydrogen-rich water protects against thioacetamide-induced hepatic encephalopathy in rats through stabilizing liver-brain disturbance.

This animal study examined Treatment with hydrogen-rich water protects against thioacetamide-induced hepatic encephalopathy in rats through stabilizing liver-brain disturbance. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: The results showed that hydrogen-rich water can improve the behavioral changes of the HE rats, reduce blood ammonia, reduce liver function damage, alleviate the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice.

This uncontrolled human study examined iTRAQ-based quantitative proteomic analysis of the therapeutic effects of 2% hydrogen gas inhalation on brain injury in septic mice. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: The results of the H&E, and Nissl staining indicated that the CLP mice had a significant brain injury, which was characterized by aggravated pathological…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins.

This animal study examined Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Based on our results, HRW treatment was able to reduce brain infarct volume and improve neurological function following ischemic brain injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen rich saline reduces immune-mediated brain injury in rats with acute carbon monoxide poisoning.

This animal study examined Hydrogen rich saline reduces immune-mediated brain injury in rats with acute carbon monoxide poisoning. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: CO-exposed rats showed the increase in neuron loss and the decrease in antioxidant capacities. And H(2) rich saline given after CO poisoning can prevent…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats.

This animal study examined Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results indicated that hSCI significantly decreased the hind limb neurological function, testis index, MSTD, and MSET, and induced severe testicular morphological injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen exerts neuroprotective effects by inhibiting oxidative stress in experimental diabetic peripheral neuropathy rats.

This animal study examined Hydrogen exerts neuroprotective effects by inhibiting oxidative stress in experimental diabetic peripheral neuropathy rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation and hydrogen-rich saline. The abstract reports: Further studies showed that hydrogen significantly upregulated the expression of nuclear factor erythroid-2-related factor 2 and downstream proteins such as catalase and hemeoxygenase-1 in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen alleviates hypoxic-ischaemic brain damage in neonatal rats by inhibiting injury of brain pericytes.

This animal study examined Hydrogen alleviates hypoxic-ischaemic brain damage in neonatal rats by inhibiting injury of brain pericytes. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that HRW significantly attenuated HI-induced oxidative stress in the brain pericytes of neonatal rats, partly through the Nrf2-HO-1 pathway, further improving…. This is an automated editorial draft based on the abstract and requires source review before publication.

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