Protective effects of hydrogen-rich saline against renal ischemia-reperfusion injury by increased expression of heme oxygenase-1 in aged rats.

This animal study examined Protective effects of hydrogen-rich saline against renal ischemia-reperfusion injury by increased expression of heme oxygenase-1 in aged rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS improves the renal response to I/R in aged rats, possibly by reducing oxidative stress and upregulating HO-1 gene expression. This is an automated editorial draft based on the abstract and requires source review before publication.

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UPLC/MS-Based Metabolomics Investigation of the Protective Effect of Hydrogen Gas Inhalation on Mice with Calcium Oxalate-Induced Renal Injury.

This animal study examined UPLC/MS-Based Metabolomics Investigation of the Protective Effect of Hydrogen Gas Inhalation on Mice with Calcium Oxalate-Induced Renal Injury. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: This study showed the effects of hydrogen on serum and urine metabolites in a renal injury model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline Promotes the Recovery of Renal Function after Ischemia/Reperfusion Injury in Rats via Anti-apoptosis and Anti-inflammation.

This animal study examined Hydrogen-Rich Saline Promotes the Recovery of Renal Function after Ischemia/Reperfusion Injury in Rats via Anti-apoptosis and Anti-inflammation. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRSS showed a protective effect in the prevention of renal injury and could promote renal function recovery after I/R injury in rats. HRSS might…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Oral hydrogen water prevents chronic allograft nephropathy in rats.

This animal study examined Oral hydrogen water prevents chronic allograft nephropathy in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline ameliorates renal injury induced by unilateral ureteral obstruction in rats.

This animal study examined Hydrogen-rich saline ameliorates renal injury induced by unilateral ureteral obstruction in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 10 days. The abstract reports: Hydrogen has been demonstrated to have effective protection against tissue injuries caused by oxidative stress, inflammation, and apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Pretreatment with hydrogen-rich saline reduces the damage caused by glycerol-induced rhabdomyolysis and acute kidney injury in rats.

This animal study examined Pretreatment with hydrogen-rich saline reduces the damage caused by glycerol-induced rhabdomyolysis and acute kidney injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Pretreatment by HRS ameliorated renal dysfunction in glycerol-induced rhabdomyolysis by inhibiting oxidative stress and the inflammatory response. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of hydrogen-rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation.

This uncontrolled human study examined Effects of hydrogen-rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. The abstract reports: Hydrogen can attenuate severe burn-induced early AKI; the mechanisms of protection include the inhibition of oxidative stress induced apoptosis and inflammation, which may be…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice.

This animal study examined Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice. The abstract describes Mouse model; reported duration 5 days. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of Hydrogen Gas Is Beneficial for Preventing Contrast-Induced Acute Kidney Injury in Rats.

This animal study examined Inhalation of Hydrogen Gas Is Beneficial for Preventing Contrast-Induced Acute Kidney Injury in Rats. The abstract describes Rat model. The abstract reports: Results: One day after the injection, serum levels of urea nitrogen were significantly lower in H gas-inhaling CIAKI rats (17.6 ± 2.3 mg/dl) than…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of 4% and 67% hydrogen ameliorates oxidative stress, inflammation, apoptosis, and necroptosis in a rat model of glycerol-induced acute kidney injury

This animal study examined Inhalation of 4% and 67% hydrogen ameliorates oxidative stress, inflammation, apoptosis, and necroptosis in a rat model of glycerol-induced acute kidney injury. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: After 72 hours of glycerol injection (8 mL/kg), we found that glycerol triggered oxidative stress, inflammatory reactions, and apoptotic events. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of hydrogen-rich water in a rat model of polycystic kidney disease

This observational study examined Effects of hydrogen-rich water in a rat model of polycystic kidney disease. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: This experiment showed that the effect of drinking large volumes of hydrogen-rich water was not significantly different from that of normal water, in terms…. This is an automated editorial draft based on the abstract and requires source review before publication.

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H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain.

This animal study examined H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain. The abstract describes Rat model. The abstract reports: We found that H2 clearly inhibited hyperalgesia and allodynia in neuropathic pain and also attenuated the pro-inflammatory cytokines TNF-α, IL-1β, and high-mobility group box…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice.

This animal study examined The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice. The abstract describes Mouse model. The abstract reports: In the case of infected groups, the group fed ERW (ERW+E. hortense group) showed the result that IL-4, IL-5, IL-10 and Ig A expression…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen increases resilience to stress in mice.

This animal study examined Molecular hydrogen increases resilience to stress in mice. The abstract describes Mouse model; hydrogen delivered as oxyhydrogen. The abstract reports: The results showed that repeated inhalation of hydrogen-oxygen mixed gas [67%:33% (V/V)] significantly decreased both the acute and chronic stress-induced depressive- and anxiety-like behaviors…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Impact of molecular hydrogen treatments on the innate immune activity and survival of zebrafish (Danio rerio) challenged with Aeromonas hydrophila.

This animal study examined Impact of molecular hydrogen treatments on the innate immune activity and survival of zebrafish (Danio rerio) challenged with Aeromonas hydrophila. The abstract describes Zebrafish model; hydrogen delivered as hydrogen water. The abstract reports: We have found an increased survival rate of bacteria-challenged zebrafish subjected to the HRW immersion treatment. This is an automated editorial draft based on the abstract and requires source review before publication.

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