Hydrogen‐Rich Water Improves Cognitive Ability and Induces Antioxidative, Antiapoptotic, and Anti‐Inflammatory Effects in an Acute Ischemia‐Reperfusion Injury Mouse Model

This animal study examined Hydrogen‐Rich Water Improves Cognitive Ability and Induces Antioxidative, Antiapoptotic, and Anti‐Inflammatory Effects in an Acute Ischemia‐Reperfusion Injury Mouse Model. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen treatment could potentially be a future therapeutic strategy for ischemia and its derived neurodegenerative diseases by improving cognitive abilities and inducing antioxidative and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas alleviates sepsis-induced neuroinflammation and cognitive impairment through regulation of DNMT1 and DNMT3a-mediated BDNF promoter IV methylation in mice.

This uncontrolled human study examined Hydrogen gas alleviates sepsis-induced neuroinflammation and cognitive impairment through regulation of DNMT1 and DNMT3a-mediated BDNF promoter IV methylation in mice. The abstract describes Human participants. The abstract reports: We found that 2% H inhalation can reduce pro-inflammatory factors, alleviate DNMT1, DNMT3a but not DNMT3b expression, make hypomethylation of BDNF promoter IV at…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Different effects of hydrogen-rich water intake and hydrogen gas inhalation on gut microbiome and plasma metabolites of rats in health status.

This animal study examined Different effects of hydrogen-rich water intake and hydrogen gas inhalation on gut microbiome and plasma metabolites of rats in health status. The abstract describes Rat model; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: Pathway enrichment analysis showed that HRW intake mainly affected starch and sucrose metabolism, and DMs in HI group were mainly enriched in arginine biosynthesis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model.

This animal study examined Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation; reported duration 30 min. The abstract reports: Our results demonstrated that TMT exposure alters seizure and spatial recognition memory. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline reverses oxidative stress, cognitive impairment, and mortality in rats submitted to sepsis by cecal ligation and puncture.

This animal study examined Hydrogen-rich saline reverses oxidative stress, cognitive impairment, and mortality in rats submitted to sepsis by cecal ligation and puncture. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: These findings indicate that HRS could attenuate the consequences of sepsis induced by cecal ligation and puncture in rats, at least in part, by…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline Ameliorates Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice Via the Nrf2-ARE Signaling Pathway.

This animal study examined Hydrogen-Rich Saline Ameliorates Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice Via the Nrf2-ARE Signaling Pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: We found that HRS reduced the severity of EAE in mice and alleviated inflammation and demyelination. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen inhalation attenuates postoperative cognitive impairment in rats.

This animal study examined Molecular hydrogen inhalation attenuates postoperative cognitive impairment in rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Many studies have found that molecular hydrogen (H2) has significant neuroprotection against acute and chronic neurological injury by regulating inflammation and apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Drinking hydrogen water ameliorated cognitive impairment in senescence-accelerated mice.

This in vitro or cellular study examined Drinking hydrogen water ameliorated cognitive impairment in senescence-accelerated mice. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water; reported duration 30 days. The abstract reports: On the basis of our results, hydrogen water merits further investigation for possible therapeutic/preventative use for age-related cognitive disorders. This is an automated editorial draft based on the abstract and requires source review before publication.

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FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia.

This animal study examined FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Autophagy, a self-cannibalization mechanism, has been demonstrated to be involved in VD progression. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of Hydrogen-Rich Saline on Hepatectomy-Induced Postoperative Cognitive Dysfunction in Old Mice.

This animal study examined Effects of Hydrogen-Rich Saline on Hepatectomy-Induced Postoperative Cognitive Dysfunction in Old Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Modulates T Cell Differentiation and Enhances Neuro-Regeneration in a Vascular Dementia Mouse Model

This animal study examined Molecular Hydrogen Modulates T Cell Differentiation and Enhances Neuro-Regeneration in a Vascular Dementia Mouse Model. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water. The abstract reports: Histological examinations showed pyknotic neuronal morphologies and elevated reactive oxygen species (ROS) in the VaD hippocampus, whereas H administration mitigated these alterations. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas alleviates blood-brain barrier impairment and cognitive dysfunction of septic mice in an Nrf2-dependent pathway

This animal study examined Hydrogen gas alleviates blood-brain barrier impairment and cognitive dysfunction of septic mice in an Nrf2-dependent pathway. The abstract describes Mouse model. The abstract reports: We found that H can improve survival in septic mice, decrease escape latency and platform crossing times, decrease pro-inflammatory cytokines and oxidative product levels…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice.

This animal study examined Hydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: We found that prophylactic administration of both 0.36mM and 0.89mM HRW was able to delay EAE onset and reduce maximum clinical scores. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Anti-Inflammatory Effect of Hydrogen Gas Inhalation and Its Influence on Laser-Induced Choroidal Neovascularization in a Mouse Model of Neovascular Age-Related Macular Degeneration

This animal study examined The Anti-Inflammatory Effect of Hydrogen Gas Inhalation and Its Influence on Laser-Induced Choroidal Neovascularization in a Mouse Model of Neovascular Age-Related Macular Degeneration. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: H inhalation could alleviate CNV leakage in a laser-induced mouse CNV model, and the potential mechanism might be related to the suppression of the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats

This animal study examined A new insight into the molecular hydrogen effect on coenzyme Q and mitochondrial function of rats. The abstract describes Rat model. The abstract reports: In this paper, we demonstrated that consumption of H-rich water (HRW) resulted in stimulated rat cardiac mitochondrial electron respiratory chain function and increased levels…. This is an automated editorial draft based on the abstract and requires source review before publication.

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