Effects of Hydrogen-rich Water on the PI3K/AKT Signaling Pathway in Rats with Myocardial Ischemia-reperfusion Injury.
This animal study examined Effects of Hydrogen-rich Water on the PI3K/AKT Signaling Pathway in Rats with Myocardial Ischemia-reperfusion Injury. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 10 min. The abstract reports: Hydrogen-rich water can activate the PI3K/AKT signaling pathway, alleviate ischemia-reperfusion injury in isolated rat hearts, and inhibit cardiomyocyte apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Modulates the Baroreflex Activity and Reduces the Vascular Adrenoreceptor Sensitivity to Phenylephrine and Lung Inflammation in Rats with Pulmonary Hypertension.
This animal study examined Molecular Hydrogen Modulates the Baroreflex Activity and Reduces the Vascular Adrenoreceptor Sensitivity to Phenylephrine and Lung Inflammation in Rats with Pulmonary Hypertension. The abstract describes Rat model. The abstract reports: No differences in HR response to PE administration were found between any of the experimental groups. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline mitigates pressure overload-induced cardiac hypertrophy and atrial fibrillation in rats via the JAK-STAT signalling pathway.
This animal study examined Hydrogen-rich saline mitigates pressure overload-induced cardiac hypertrophy and atrial fibrillation in rats via the JAK-STAT signalling pathway. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: HRS was found to mitigate cardiac hypertrophy induced by pressure overload in rats and reduce atrial fibrosis and AF which was possibly achieved via…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMetabolomics Analysis of the Effect of Hydrogen-Rich Water on Myocardial Ischemia-Reperfusion Injury in Rats.
This animal study examined Metabolomics Analysis of the Effect of Hydrogen-Rich Water on Myocardial Ischemia-Reperfusion Injury in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model
This animal study examined Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: H2 inhalation after shock stabilized hemodynamics and improved survival rates in an HS/R model independent of XOR. The therapeutic action of H2 was partially…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas with hypothermic machine perfusion induces lipidomic alterations in donation-after-cardiac-death rat livers.
This animal study examined Hydrogen gas with hypothermic machine perfusion induces lipidomic alterations in donation-after-cardiac-death rat livers. The abstract describes Rat model. The abstract reports: The analysis results revealed distinct lipid metabolic alterations across cold storage, machine perfusion (MP), and hydrogen-supplemented perfusion (MP-H2) groups compared to healthy controls. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation alleviates myocardial ischemia-reperfusion injury by the inhibition of oxidative stress and NLRP3-mediated pyroptosis in rats.
This animal study examined Hydrogen gas inhalation alleviates myocardial ischemia-reperfusion injury by the inhibition of oxidative stress and NLRP3-mediated pyroptosis in rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: We found that oxidative stress and NLRP3 mediated pyroptosis are the important mechanisms for hydrogen to alleviate myocardial I/R injury, and we also confirmed…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHigh-concentration hydrogen protects mouse heart against ischemia/reperfusion injury through activation of thePI3K/Akt1 pathway.
This animal study examined High-concentration hydrogen protects mouse heart against ischemia/reperfusion injury through activation of thePI3K/Akt1 pathway. The abstract describes Mouse model; sample size 6. The abstract reports: HCH resulted in the phosphorylation of Akt1 but not Akt2, and Akt1 inhibition markedly abolished HCH-induced cardioprotection. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBeneficial effects of hydrogen gas on porcine liver reperfusion injury with use of total vascular exclusion and active venous bypass.
This animal study examined Beneficial effects of hydrogen gas on porcine liver reperfusion injury with use of total vascular exclusion and active venous bypass. The abstract describes Porcine model; hydrogen delivered as injected or infused hydrogen; reported duration 60 minutes. The abstract reports: The solution containing hydrogen gas was safe and had remarkably protective effects on the porcine during liver I/R and may be applied in the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCardioprotective Effect of Hydrogen-rich Saline on Isoproterenol-induced Myocardial Infarction in Rats.
This animal study examined Cardioprotective Effect of Hydrogen-rich Saline on Isoproterenol-induced Myocardial Infarction in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: From these results, hydrogen-rich saline exerts cardiovascular protective effects against isoproterenol-induced MI at least in part via interactions which evoke antioxidant and anti-inflammatory activities. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation ameliorates cardiac remodelling and fibrosis by regulating NLRP3 inflammasome in myocardial infarction rats
This in vitro or cellular study examined Hydrogen gas inhalation ameliorates cardiac remodelling and fibrosis by regulating NLRP3 inflammasome in myocardial infarction rats. The abstract describes Fibroblast model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results showed that hydrogen gas can significantly improve cardiac function and reduce the area of cardiac fibrosis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen attenuates sepsis-induced cardiomyopathy in mice by promoting autophagy.
This uncontrolled human study examined Molecular hydrogen attenuates sepsis-induced cardiomyopathy in mice by promoting autophagy. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Hydrogen exerts protective effect against SIC, which may be achieved through the promotion of autophagy and mitophagy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Attenuates Thyroid Hormone-Induced Cardiac Hypertrophy in Rats by regulating angiotensin II type 1 receptor and NADPH oxidase 2 mediated oxidative stress.
This animal study examined Hydrogen Attenuates Thyroid Hormone-Induced Cardiac Hypertrophy in Rats by regulating angiotensin II type 1 receptor and NADPH oxidase 2 mediated oxidative stress. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Cardiac hypertrophy occurs as a result of high levels of thyroid hormone, which may contribute to heart failure and is closely related to oxidative…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDrinking Molecular Hydrogen Water Is Beneficial to Cardiovascular Function in Diet-Induced Obesity Mice.
This animal study examined Drinking Molecular Hydrogen Water Is Beneficial to Cardiovascular Function in Diet-Induced Obesity Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 2 weeks. The abstract reports: Furthermore, the results of a colony formation assay of bone-marrow-derived endothelial progenitor cells (EPCs) indicated that MHW activated the expansion, differentiation, and mobilization of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective Effects of Hydrogen on Myocardial Mitochondrial Functions in Septic Mice.
This animal study examined Protective Effects of Hydrogen on Myocardial Mitochondrial Functions in Septic Mice. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
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