Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.

This animal study examined Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress. The abstract describes Mouse model. The abstract reports: Within 1 wk after whole thorax irradiation, immunohistochemistry and immunoblotting showed that H(2) treatment reduced oxidative stress and apoptosis, measures of acute damage, in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of hydrogen-rich saline against radiation-induced immune dysfunction.

This animal study examined Protective effect of hydrogen-rich saline against radiation-induced immune dysfunction. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Recent studies showed that hydrogen can be used as an effective radioprotective agent through scavenging free radicals. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline protects immunocytes from radiation-induced apoptosis.

This animal study examined Hydrogen-rich saline protects immunocytes from radiation-induced apoptosis. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: This study suggests that H2 protected the immune system and alleviated the hematological injury induced by IR. This is an automated editorial draft based on the abstract and requires source review before publication.

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The healing effect of hydrogen-rich water on acute radiation-induced skin injury in rats.

This animal study examined The healing effect of hydrogen-rich water on acute radiation-induced skin injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: Furthermore, interventions of HRW resulted in a marked reduction in the MDA (P < 0.05) and IL-6 levels (P < 0.01). This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88’s effects on the gut microbiota.

This animal study examined Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88’s effects on the gut microbiota. The abstract describes Mouse model. The abstract reports: In the present study, we found that oral gavage with hydrogen-water increased the survival rate and body weight of mice exposed to total abdominal…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen protects auditory hair cells from cisplatin-induced free radicals.

Cisplatin is a widely used chemotherapeutic agent for the treatment of various malignancies. However, its maximum dose is often limited by severe ototoxicity. Cisplatin ototoxicity may require the production of reactive oxygen species (ROS) in the inner ear by activating enzymes specific to the cochlea.

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Histological study on the effect of electrolyzed reduced water-bathing on UVB radiation-induced skin injury in hairless mice.

This animal study examined Histological study on the effect of electrolyzed reduced water-bathing on UVB radiation-induced skin injury in hairless mice. The abstract describes Mouse model. The abstract reports: We found that UVB-mediated skin injury of ERW-bathing group was significantly low compared to TW control group in the early stage of experiment. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Inhalation Protects against Ototoxicity Induced by Intravenous Cisplatin in the Guinea Pig.

This animal study examined Hydrogen Inhalation Protects against Ototoxicity Induced by Intravenous Cisplatin in the Guinea Pig. The abstract describes Animal model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Ototoxicity may be reduced by co-administration of an otoprotective agent, but the results in humans have so far been modest. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline attenuates chemotherapy-induced ovarian injury via regulation of oxidative stress.

This animal study examined Hydrogen-rich saline attenuates chemotherapy-induced ovarian injury via regulation of oxidative stress. The abstract describes Rat model; sample size 60; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Mitigating radiation-induced brain injury via NLRP3/NLRC4/Caspase-1 pyroptosis pathway: Efficacy of memantine and hydrogen-rich water.

This uncontrolled human study examined Mitigating radiation-induced brain injury via NLRP3/NLRC4/Caspase-1 pyroptosis pathway: Efficacy of memantine and hydrogen-rich water. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Particularly, hydrogen-rich water showed a promising reduction in these symptoms. This is an automated editorial draft based on the abstract and requires source review before publication.

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Long-Term Neuroprotective Effects of Hydrogen-Rich Water and Memantine in Chronic Radiation-Induced Brain Injury: Behavioral, Histological, and Molecular Insights.

This animal study examined Long-Term Neuroprotective Effects of Hydrogen-Rich Water and Memantine in Chronic Radiation-Induced Brain Injury: Behavioral, Histological, and Molecular Insights. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 60 days. The abstract reports: Histological results revealed that HRW reduced neuronal swelling, degeneration, and loss and enhanced dendritic spine density and neurogenesis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of dissolved molecular hydrogen against hydrogen peroxide-, hydroperoxide-, and glyoxal-induced injuries to human skin keratinocytes

This in vitro or cellular study examined Protective effects of dissolved molecular hydrogen against hydrogen peroxide-, hydroperoxide-, and glyoxal-induced injuries to human skin keratinocytes. The abstract describes HaCaT keratinocyte model. The abstract reports: Our results showed that H exerted cytoprotective effects against stress induced by HO, t-BuOOH, and glyoxal. This is an automated editorial draft based on the abstract and requires source review before publication.

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Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson’s disease

This animal study examined Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson’s disease. The abstract describes Rat model. The abstract reports: In conclusion, the PD animal model showed increased intestinal permeability together with hepatic inflammation correlated with altered gut microbiota. This is an automated editorial draft based on the abstract and requires source review before publication.

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Randomized double-blind placebo-controlled trial of hydrogen inhalation for Parkinson’s disease: a pilot study

Oxidative stress is involved in the progression of Parkinson's disease (PD). Recent studies have confirmed that molecular hydrogen (H) functions as a highly effective antioxidant in animal models of PD. A placebo-controlled, randomized, double-blind, parallel-group clinical pilot study was conducted to assess the efficacy of hydrogen gas inhalation in Japanese patients with PD on treatment with levodopa.

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Therapeutic Effects of Hydrogen in Animal Models of Parkinson’s Disease

This in vitro or cellular study examined Therapeutic Effects of Hydrogen in Animal Models of Parkinson’s Disease. The abstract describes Cell culture / in vitro model. The abstract reports: Thus, it is strongly suggested that hydrogen might provide a great advantage to prevent or minimize the onset and progression of PD. This is an automated editorial draft based on the abstract and requires source review before publication.

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