Hydrogen-rich medium protects human skin fibroblasts from high glucose or mannitol induced oxidative damage.
This in vitro or cellular study examined Hydrogen-rich medium protects human skin fibroblasts from high glucose or mannitol induced oxidative damage. The abstract describes Fibroblast model. The abstract reports: The results revealed that both mannitol and high glucose could cause oxidative stress in HSFs. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen saline on diabetic retinopathy in a streptozotocin-induced diabetic rat model.
This animal study examined Protective effects of hydrogen saline on diabetic retinopathy in a streptozotocin-induced diabetic rat model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 4 weeks. The abstract reports: Our preliminary studies indicated that H(2) saline may have potentials in the clinical treatment of diabetic retinopathy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Therapy Attenuates Inflammatory Pathway Signaling in Septic Mice.
This animal study examined Hydrogen Gas Therapy Attenuates Inflammatory Pathway Signaling in Septic Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: These findings may contribute to clarifying the mechanism of action of H therapy in sepsis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Nano-Bubble Water Suppresses ROS Generation, Adipogenesis, and Interleukin-6 Secretion in Hydrogen-Peroxide- or PMA-Stimulated Adipocytes and Three-Dimensional Subcutaneous Adipose Equivalents.
This in vitro or cellular study examined Hydrogen Nano-Bubble Water Suppresses ROS Generation, Adipogenesis, and Interleukin-6 Secretion in Hydrogen-Peroxide- or PMA-Stimulated Adipocytes and Three-Dimensional Subcutaneous Adipose Equivalents. The abstract describes HaCaT keratinocyte model. The abstract reports: Nanoparticle tracking analysis showed that fresh HW contains 1.17 × 10/mL of nano-sized hydrogen bubbles. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study.
This uncontrolled human study examined Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study. The abstract describes Human participants; sample size 20; hydrogen delivered as hydrogen water; reported duration 8 weeks. The abstract reports: The consumption of hydrogen rich water for 8 weeks resulted in a 39% increase (p. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water inhibits glucose and α,β -dicarbonyl compound-induced reactive oxygen species production in the SHR.Cg-Leprcp/NDmcr rat kidney.
This uncontrolled human study examined Hydrogen-rich water inhibits glucose and α,β -dicarbonyl compound-induced reactive oxygen species production in the SHR.Cg-Leprcp/NDmcr rat kidney. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: These results indicate that HRW inhibits the production of α,β-dicarbonyl compounds and ROS in the kidneys of SHR.Cg-Leprcp/NDmcr rats. Therefore, it has therapeutic potential…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich water on abnormalities in a SHR.Cg-Leprcp/NDmcr rat – a metabolic syndrome rat model
This animal study examined Effects of hydrogen-rich water on abnormalities in a SHR.Cg-Leprcp/NDmcr rat – a metabolic syndrome rat model. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 16 weeks. The abstract reports: The present findings suggest that HRW conferred significant benefits against abnormalities in the metabolic syndrome model rats, at least by preventing and ameliorating glomerulosclerosis…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects rat from oxygen glucose deprivation and reperusion-induced apoptosis through VDAC1 via Bcl-2.
This animal study examined Hydrogen-rich saline protects rat from oxygen glucose deprivation and reperusion-induced apoptosis through VDAC1 via Bcl-2. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS ameliorated OGD/RP-induced PC-12 cell apoptosis and provided a novel treatment option for ischemia. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome.
This uncontrolled human study examined Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome. The abstract describes Human participants; sample size 20; hydrogen delivered as hydrogen water; reported duration 10 weeks. The abstract reports: We have found that hydrogen (dihydrogen; H2) has beneficial lipid-lowering effects in high-fat diet-fed Syrian golden hamsters. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice.
This in vitro or cellular study examined Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice. The abstract describes Fibroblast model. The abstract reports: To examine how drinking H(2)-water improves obesity and metabolic parameters at the molecular level, we examined gene-expression profiles, and found enhanced expression of a…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of hydrogen-rich water on the lactic acid level in metformin-treated diabetic rats under hypoxia.
This uncontrolled human study examined Effect of hydrogen-rich water on the lactic acid level in metformin-treated diabetic rats under hypoxia. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: We found that the levels of lactic acid, pyruvate and lactate dehydrogenase were significantly lower in the blood of DMMHR group than DMMH group. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSuppressive effects of electrolyzed reduced water on alloxan-induced apoptosis and type 1 diabetes mellitus.
This animal study examined Suppressive effects of electrolyzed reduced water on alloxan-induced apoptosis and type 1 diabetes mellitus. The abstract describes Mouse model. The abstract reports: Here, we showed that electrolyzed reduced water prevented alloxan-induced DNA fragmentation and the production of cells in sub-G1 phase in HIT-T15 pancreatic β-cells. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ.
This animal study examined Hydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The present study evaluated the effects of H2 on NAFLD in rats and concluded that H2‑rich saline had significant therapeutic effects on NAFLD induced…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreElectrolyzed hydrogen-rich water for oxidative stress suppression and improvement of insulin resistance: a multicenter prospective double-blind randomized control trial.
Electrolyzed hydrogen-rich water (EHW) is known to have suppressive effects on oxidative stress (OS). However, its benefit in type 2 diabetes mellitus (T2DM) remains unclear. This study aimed to investigate the effect of EHW on T2DM.
Read MorePreservative effect of electrolyzed reduced water on pancreatic beta-cell mass in diabetic db/db mice.
This animal study examined Preservative effect of electrolyzed reduced water on pancreatic beta-cell mass in diabetic db/db mice. The abstract describes Mouse model. The abstract reports: The present data suggest that ERW may protects beta-cell damage and would be useful for antidiabetic agent. This is an automated editorial draft based on the abstract and requires source review before publication.
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