Hydrogen-Rich Saline Attenuates Chronic Allodynia after Bone Fractures via Reducing Spinal CXCL1/CXCR2-Mediated Iron Accumulation in Mice.
This animal study examined Hydrogen-Rich Saline Attenuates Chronic Allodynia after Bone Fractures via Reducing Spinal CXCL1/CXCR2-Mediated Iron Accumulation in Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These findings identify that hydrogen-rich saline confers protection against fracture-caused chronic allodynia via spinal down-modulation of CXCL1-dependent TfR1-mediated iron accumulation in mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Prevents Osteoclast Activation in a Glucocorticoid-Induced Osteoporosis Zebrafish Scale Model.
This animal study examined Molecular Hydrogen Prevents Osteoclast Activation in a Glucocorticoid-Induced Osteoporosis Zebrafish Scale Model. The abstract describes Zebrafish model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of H 2 treatment in a mouse model of rheumatoid arthritis‐associated interstitial lung disease
This uncontrolled human study examined Effect of H 2 treatment in a mouse model of rheumatoid arthritis‐associated interstitial lung disease. The abstract describes Human participants. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen (H) Alleviates Osteoarthritis by Inhibiting Apoptosis and Inflammation via the JNK Signaling Pathway.
This animal study examined Hydrogen (H) Alleviates Osteoarthritis by Inhibiting Apoptosis and Inflammation via the JNK Signaling Pathway. The abstract describes Mouse model. The abstract reports: We uncovered that hydrogen (H) could alleviate apoptosis response and ECM degradation in human chondrocytes via inhibiting the activation of the JNK signaling pathway.…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen treatment reduces tendon adhesion and inflammatory response.
This animal study examined Hydrogen treatment reduces tendon adhesion and inflammatory response. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTherapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study.
This randomized controlled trial examined Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study. The abstract describes Human participants; hydrogen delivered as injected or infused hydrogen; reported duration 5 days. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates ischemia-reperfusion injury in skeletal muscle.
This animal study examined Hydrogen-rich saline attenuates ischemia-reperfusion injury in skeletal muscle. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS seems to be effective in attenuating IR injury in skeletal muscle via its antioxidant, anti-apoptosis, and anti-autophagy effect. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConsumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study.
This uncontrolled human study examined Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: The results suggest that the hydroxyl radical scavenger H2 effectively reduces oxidative stress in patients with this condition. The symptoms of RA were significantly…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreImprovement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases.
This uncontrolled human study examined Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases. The abstract describes Human participants; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen: new antioxidant and anti-inflammatory therapy for rheumatoid arthritis and related diseases.
This uncontrolled human study examined Molecular hydrogen: new antioxidant and anti-inflammatory therapy for rheumatoid arthritis and related diseases. The abstract describes Human participants. The abstract reports: It is also associated with an increased risk of atherosclerosis, which can result in cardiovascular disease and mortality. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide.
This animal study examined Molecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide. The abstract describes Rat model. The abstract reports: These results imply that one of the functions of H2 exhibits cytoprotective effects and transcriptional alterations through reducing ONOO-. Moreover, novel pharmacological strategies aimed…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas protects against ovariectomy-induced osteoporosis by inhibiting NF-κB activation.
This animal study examined Hydrogen gas protects against ovariectomy-induced osteoporosis by inhibiting NF-κB activation. The abstract describes Mouse model. The abstract reports: H2 markedly inhibited RANKL-induced activation, nuclear translocation, and transcriptional activity of NF-κB (P These results demonstrated that H2 could be an effective therapeutic agent…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTreatment with hydrogen molecule alleviates TNFα-induced cell injury in osteoblast.
This animal study examined Treatment with hydrogen molecule alleviates TNFα-induced cell injury in osteoblast. The abstract describes Rat model. The abstract reports: Recently, it has been demonstrated that hydrogen gas, known as a novel antioxidant, can exert therapeutic anti-inflammatory effect in many diseases. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages.
This animal study examined Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: However, we have recently demonstrated that hydrogen inhibits type I allergy through modulating intracellular signal transduction. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePreventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet.
This animal study examined Preventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Obese rats, induced by a high-fat diet, showed a higher gingival level of 8-hydroxydeoxyguanosine and a lower level of alveolar bone density compared to…. This is an automated editorial draft based on the abstract and requires source review before publication.
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