RETRACTED: Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer’s disease

This animal study examined RETRACTED: Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer’s disease. The abstract describes Rat model; sample size 18; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 10 days. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation—Fantasy or Reality?

This in vitro or cellular study examined Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation—Fantasy or Reality?. The abstract describes Cell culture / in vitro model. The abstract reports: Recent studies in animal models of focal or global cerebral ischemia and cerebral ischemia in humans suggest that hydrogen has pleiotropic neuroprotective properties. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models.

This animal study examined Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models. The abstract describes Mouse model; reported duration 60 days. The abstract reports: These results suggest that H therapy can mitigate toxic metabolites in the astrocytic urea cycle, thereby reducing neurodegeneration and memory loss in AD. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer’s disease by reduction of oxidative stress.

This animal study examined Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer’s disease by reduction of oxidative stress. The abstract describes Rat model; sample size 84; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 14 days. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water ameliorates neuropathological impairments in a mouse model of Alzheimer’s disease through reducing neuroinflammation and modulating intestinal microbiota

This animal study examined Hydrogen-rich water ameliorates neuropathological impairments in a mouse model of Alzheimer’s disease through reducing neuroinflammation and modulating intestinal microbiota. The abstract describes Mouse model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 7 months. The abstract reports: The results showed that hydrogen-rich water prevented synaptic loss and neuronal death, inhibited senile plaques, and reduced hyperphosphorylated tau and neurofibrillary tangles in 3×Tg…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis.

This animal study examined Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis. The abstract describes Zebrafish model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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The role of hydrogen therapy in Alzheimer’s disease management: Insights into mechanisms, administration routes, and future challenges.

This narrative review examined The role of hydrogen therapy in Alzheimer’s disease management: Insights into mechanisms, administration routes, and future challenges. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.

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Therapeutic Inhalation of Hydrogen Gas for Alzheimer’s Disease Patients and Subsequent Long-Term Follow-Up as a Disease-Modifying Treatment: An Open Label Pilot Study.

This uncontrolled human study examined Therapeutic Inhalation of Hydrogen Gas for Alzheimer’s Disease Patients and Subsequent Long-Term Follow-Up as a Disease-Modifying Treatment: An Open Label Pilot Study. The abstract describes Human participants; reported duration 6 months. The abstract reports: To objectively assess the neuron integrity, diffusion tensor imaging (DTI) with advanced magnetic resonance imaging (MRI) was applied to neuron bundles passing through the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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