Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In this animal study, the authors report that Using a Caco-2 cell exposure model, we assessed viability, apoptosis, and LDH release.
Read ArticleH2HUBB PLAIN-LANGUAGE TAKEAWAY The study adds to the molecular-hydrogen evidence base, but the available record does not support a firm conclusion about therapeutic benefit. Hydrogen water inflammatory bowel…
Read ArticleIt highlights reports of anti-inflammatory and tissue-protective effects associated with endogenous H₂ and proposes that microbiota outside the gastrointestinal tract may also contribute to biologically relevant H₂ production.…
Read ArticleIn rats, plasma alanine aminotransferase activity and hepatic oxidized glutathione concentration were significantly lower as portal H₂ concentration increased. There was no significant difference in the population of…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Advances in sequencing and other technologies have facilitated dramatic advances in the authors' knowledge of the types and number of…
Read ArticleIn a synthetic gut microbial community, addition of the H₂-consuming human gut methanogen Methanobrevibacter smithii decreased butyrate production alongside H₂ concentration. This source-grounded publication contributes evidence relevant to…
Read ArticleThe development of oral therapeutics that concurrently attenuate intestinal inflammation, modulate gut microbiota, and ameliorate psychiatric symptoms is imperative for effective IBD management. This source-grounded publication contributes evidence…
Read ArticleAt the molecular level, H₂ inhalation suppressed the TLR4/NF-κB signaling pathway and activated the Keap1/Nrf2 antioxidant axis, leading to reduced production of pro-inflammatory cytokines and oxidative stress markers,…
Read ArticleIn a PPD mouse model, EL@HRG, acting via the gut-brain axis, inhibited hippocampal neuroinflammation, restored synaptic plasticity and GABAergic signaling, and consequently markedly improved depressive-like behaviors, anxiety, and…
Read ArticleIn C57BL/6 mice, body weight, oral glucose tolerance, and blood glucose increased significantly in the HFD group compared with the CD group (P < 0.001), and malondialdehyde levels…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The possible roles of molecular hydrogen, a common byproduct of bacterial fermentation, are also addressed. The reviewed evidence adds support…
Read ArticleThis narrative review examined oF REVIEW: In this paper, the researchers present a hypothesis that TMAO is a marker for deuterium overload in the methylation pathway, in addition…
Read ArticleIn Secondary outcomes included sensory profile [Short Sensory Profile (SSP)], gastrointestinal symptoms [Gastrointestinal Symptom Rating Scale [GSRS], Bristol Stool Form Scale [BSFS]] and Patient Health, this novel hydrogen…
Read ArticleThis publication is a scientific hypothesis or perspective about molecular hydrogen and identifies directions for further research.
Read ArticleIn mice, 3 G, preincubation of cells with ASp@BS under dark conditions led to a reduction in intracellular ROS, indicating that ASp@BS can effectively defend against oxidative stress…
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