Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
At week 8, the authors' parallel-controlled trial revealed 24.4% of patients (10/41) receiving hydrogen-water bathing achieved at least 75% improvement in Psoriasis Area Severity Index (PASI) score compared with 2.9% of patients (1/34) of the control group (Pc = 0.022, OR =…
Read ArticleIn rats, the mRNA expression of iNOS in rats with hydrogen-rich water intake was lower than that in the control group at both 3 and 7 days after…
Read ArticleIn The in vitro scratch assay showed that HW was able to diminish physical injury-induced ROS generation and promote wound healing in HGF cell monolayer sheets, lIVE/DEAD staining…
Read ArticleIn mice, hydrogen water (HW) produced by electrolysis of water has characteristics of extremely low oxidation-reduction potential (ORP) value and high dissolved hydrogen (DH). These preclinical findings add…
Read ArticleIn mice, the levels of Th2 cytokine, interleukin-5 (IL-5), and proinflammatory cytokines such as tumor necrosis factor-α and IL-6 in HW-fed mice were significantly lower than in control…
Read ArticleIn mice, hydrogen water treatment decreased serum TARC levels from 73.3±27.9 pg/mL at baseline to 53.2±18.3 pg/mL at week 4 ( p =0.0107); however, no differences were detected…
Read ArticleDaily 10 min HW (dissolved hydrogen: 338–682 μg/mL, 41 °C) bathing and skin poultice with HW-impregnated towels for 11–98 days were demonstrated to improve wrinkle degrees (29 skin-loci)…
Read ArticleIn 15 participants, the hypothesis was that H₂, through its selective antioxidant and anti-inflammatory properties, would reduce oxidative stress, modulate inflammatory pathways, and enhance skin barrier integrity, leading…
Read ArticleIn a study on a squamous cell carcinoma model in mice, Dole et al 68 conducted a high-pressure hydrogen treatment and found that mice with skin squamous cell…
Read ArticleIn mice, HRW significantly reduced plasma triglyceride and total cholesterol levels, increased high-density lipoprotein cholesterol levels, and alleviated skin lesions in mice. These preclinical findings add evidence supporting…
Read ArticleIn the iGTE, PMA/LPS significantly reduced the epithelial thickness while causing a decrease in K8/18, E-cadherin, laminin and elastin expression and an increase in COX-2 expression along with…
Read ArticleIn mice, by naked eye, the severity of skin lesions in hydrogen-rich water bath group was lower than that in distilled water bath group, and the psoriasis severity…
Read ArticleIn mice, local treatment of hydrogen-rich water shortened wound closure time and reduced the level of proinflammatory cytokines and lipid peroxidation. These preclinical findings add evidence supporting molecular…
Read ArticleIn rats, prophylactic instillation of hydrogen suppressed alkali burn-induced oxidative stress of the cornea and promoted wound healing. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleFor the Zn-500 sample, the hydrogen concentration increased to 0.02 and 0.551 ppm after 30 min and 3 h, respectively, and subsequently decreased to 0.031 ppm after 24…
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