Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In a laboratory model, total Unified Parkinson's Disease Rating Scale (UPDRS) scores in the H₂-water group (n=9) improved (median, -1.0; mean ± standard deviation, -5.7 ± 8.4), whereas UPDRS scores in the placebo group (n=8) worsened (median, 4.5; mean ± standard deviation,…
Read ArticleIn 20 patients with an 8-week washout period in 20 patients with PD, although the researchers did not observe any beneficial effect of hydrogen in the authors' short…
Read ArticleIn mice, mPTP-induced accumulation of cellular 8-oxoguanine (8-oxoG), a marker of DNA damage, and 4-hydroxynonenal (4-HNE), a marker of lipid peroxidation were significantly decreased in the nigro-striatal dopaminergic…
Read ArticleThis human publication evaluated hydrogen gas in In the midbrain of Parkinson's disease patients, hydroxyl radicals generated by the Fenton reaction cause a chain reaction of oxidation of…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. preclinical studies demonstrate promising results, clinical trials conducted thus far have yielded mixed outcomes, with some trials reporting limited or…
Read ArticleIn mice, despite the speculation, the effect of H₂ water was still observed in ghrelin-KO PD model mice. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn an animal model, H₂ inhalation reduced activated microglia in the lesioned striatum, which is consistent with the observed reduced pro-inflammatory cytokines levels. These preclinical findings add evidence…
Read ArticleIn 18 patients with PD (age 30-80 years), this novel, proof-of-concept study demonstrated that PBM+H₂ therapy is safe and reduces disease severity. This small, pilot study suggests therapeutic…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Since the landmark finding reported in 2007 found that hydrogen reduced the levels of peroxynitrite anions and hydroxyl free radicals…
Read ArticleIn mice, there are several mechanisms of how H₂ protects neuronal damage. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways…
Read ArticleHydrogen intervention, including drinking and inhaling, significantly alleviated mental disorders induced by METH abuse, and the inhalation of hydrogen also altered gut microbiota profiles in the METH abusers.…
Read ArticleIn mice, a recent study in mice has discovered that orally administered HW provokes increased gastric production of the orexic hormone ghrelin, and that this ghrelin mediates the…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Molecular hydrogen (H₂) has recently been reported to function as an anti-oxidant and anti-inflammatory agent for the treatment of several…
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