The production of high dose hydrogen gas by the AMS-H-01 for treatment of disease.
This publication is a scientific hypothesis or perspective about molecular hydrogen and identifies directions for further research.
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A potential clinical application of hydrogen-rich saline in postoperative care.
H2HUBB PLAIN-LANGUAGE TAKEAWAY The publication summarizes the rationale and available evidence for molecular hydrogen, but it does not by itself prove treatment effectiveness. Hydrogen-rich saline research study 2023:…
Read ArticleHydrogen-related enhancement of in vivo antioxidant ability in the brain of rats fed coral calcium hydride.
This animal study examined Hydrogen-related enhancement of in vivo antioxidant ability in the brain of rats fed coral calcium hydride. The abstract describes Rat model; reported duration 4…
Read ArticleAntitumor effects of nano-bubble hydrogen-dissolved water are enhanced by coexistent platinum colloid and the combined hyperthermia with apoptosis-like cell death.
In cultured tumor cells, hydrogen-rich water combined with platinum colloid showed greater antitumor activity than hydrogen-rich water alone and was associated with apoptosis-like cell changes. These findings come…
Read ArticleProtective effects of hydrogen gas against spinal cord ischemia-reperfusion injury.
In male Sprague-Dawley rats, immunofluorescence indicated the expression of glutamate transporter-1 in the spinal ischemia group was significantly decreased compared with the sham group, which was attenuated by…
Read ArticleGlobal and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010.
H2HUBB PLAIN-LANGUAGE TAKEAWAY The study adds to the molecular-hydrogen evidence base, but the available record does not support a firm conclusion about therapeutic benefit. Hydrogen inhalation copd study:…
Read ArticleThe transfer of hydrogen from inert gas to therapeutic gas.
This narrative review examined the available evidence on molecular hydrogen. The reviewed evidence supports molecular hydrogen's therapeutic potential. Additional well-designed studies are needed to clarify clinical safety and…
Read ArticleHydrogen-rich water prepared by ammonia borane can enhance rapeseed (Brassica napus L.) seedlings tolerance against salinity, drought or cadmium.
The application of 1 mM tungstate, an inhibitor of nitrate reductase (NR; an important NO synthetic enzyme), showed the similar blocking responses in the phenotype, suggesting that NR…
Read ArticleSuccessful Treatment with Hydrogen Rich Water in a Case of Chronic Graft-versus-Host Disease
H2HUBB PLAIN-LANGUAGE TAKEAWAY The study adds to the molecular-hydrogen evidence base, but the available record does not support a firm conclusion about therapeutic benefit. Hydrogen water research study…
Read ArticleHydrogen therapy: from mechanism to cerebral diseases.
This narrative review examined the available evidence on molecular hydrogen. The medicinal value of hydrogen (H₂ ) was ignored prior to research illustrating that inhalation of 2% H₂…
Read ArticleHydrogen Gas Alleviates Sepsis-Induced Brain Injury by Improving Mitochondrial Biogenesis Through the Activation of PGC-α in Mice.
In mice, the present study showed that hydrogen gas therapy increased the 7-day survival rate, improved cognitive function, increased the mitochondrial function (MMP, ATP level, complex I activity)…
Read ArticleDesign of a Functional Eye Dressing for Treatment of the Vitreous Floater.
This study evaluated a functional eye dressing designed to deliver both molecular hydrogen and oxygen around the eye. In uncontrolled clinical observations involving 28 patients, the authors reported…
Read ArticleAbstract 10368: The Safety and Tolerability of Prolonged Inhalation of Hydrogen Gas in Air: A Phase I Clinical Trial
In 8 healthy participants, these data will be foundational to future interventional studies of inhaled H₂ in injury states, including following cardiac arrest. These findings add human evidence…
Read ArticleHydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects.
This preclinical study evaluated molecular hydrogen in rats. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to…
Read ArticleHydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β Signaling Pathway in Rats.
Hydrogen improved microvascular endothelial-cell viability partly through PI3K/Akt/GSK3β activation and inhibition of autophagy in a traumatic-brain-injury model. These findings come from a laboratory model and suggest molecular hydrogen's…
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