Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In 20 patients with LAHNC, a retrospective study of 16 patients receiving IMRT showed that daily inhalation of 5% H₂ for 30 min significantly attenuated radiation-induced bone marrow suppression, with higher white blood cell and platelet counts compared with controls, without apparent…
Read ArticleIn male C57BL/6 mice, mK-801 administration significantly reduced HORAC levels, whereas hydrogen gas therapy markedly restored them. These preclinical findings add evidence about the molecular-hydrogen effects, outcomes, and…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The biological effects of molecular hydrogen are moving beyond the traditional explanatory framework of "selective antioxidation." This article systematically integrates…
Read ArticleIn rats, hRS decreased P-selectin expression, release of thromboxane B2, ROS, and fibrinogen binding, but enhanced NO levels in H₂O₂-exposed platelets. These preclinical findings add evidence supporting molecular…
Read ArticleIn For human ex vivo studies, the researchers collected blood samples from six healthy humans and added normal saline or hydrogen-rich saline to blood and platelet-rich plasma, collagen-induced…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleIn a laboratory model, pro-inflammatory factors and CD16/32 in M1 macrophages were decreased, and the expression of CD16/32 in lamina propria were inhibited after treatment with hydrogen, but…
Read ArticleIn a laboratory model, mechanistically, a sustained supply of hydrogen molecules induces anti-inflammatory M2 macrophage polarization in time by enhancing CCL2 (chemokine C-C motif ligand 2) expression to…
Read ArticleThe researchers observed that hydrogen treatment partially reversed the increase in lung tissue density and reduced pulmonary inflammation. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleThe researchers observed that anxiety/depression-like behaviors in experimental autoimmune encephalomyelitis (EAE) mice were alleviated by MgH2 treatment. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleThe researchers found that H₂-O₂ mixture blocked c-Jun N-terminal kinase- (JNK-) MAPK activation, increased the ratio of Bcl-2/Bax, and inhibited caspase 3 cleavage to protect against CIH-induced cardiac…
Read ArticleERW treatment induced apoptosis of breast cancer cell lines independently of the status of p53 and ER and PR receptors, electrochemical reduced water (ERW) has been proposed to…
Read ArticleIn an animal model, regarding the neurological score, the piglets in the TH-H₂ group consistently had the highest score from day 2 to 5 and showed a significantly…
Read ArticleIn an animal model, the released hydrogen gas can effectively regulate redox homeostasis and mitigate excessive inflammation, and the silicic acid can promote the proliferation of reparative cells…
Read ArticleIn a laboratory model, hydrogen administration also promoted mitochondrial biogenesis and significantly decreased lactate production. The authors concluded that preconditioning lung grafts using inhaled hydrogen attenuated these proinflammatory…
Read Article