Assessment of antibacterial effect of hydrogen water on plaque from patients with chronic periodontitis.
Aarati Nayak, Akanksha Bhatt, Kishore Bhat, Ranganath Nayak, Amruta Hooli, Sachita Naik · Journal of Indian Society of Periodontology · 2021
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
In 20 patients, hydrogen water showed antibacterial activity against aerobic and anaerobic organisms associated with chronic periodontitis. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
What the Findings Mean
H2HUBB reviewed how hydrogen-rich water affected the outcomes measured in 20 patients. Hydrogen water showed antibacterial activity against aerobic and anaerobic organisms associated with chronic periodontitis.
What the Researchers Studied
The researchers studied 20 patients. The study used a human clinical study. The comparison condition was control condition or baseline measurements.
What Effects Did Molecular Hydrogen Have?
Source-reported hydrogen exposure: 1 mL hydrogen-rich water per reported dose; dissolved H₂ concentration was not sufficiently reported, so H2HUBB did not estimate milligrams of H₂. Hydrogen water showed antibacterial activity against aerobic and anaerobic organisms associated with chronic periodontitis. The authors concluded that the data of the present study indicate that hydrogen water has an antibacterial effect on microorganisms associated with chronic periodontitis. Recent studies also indicate that treatment with hydrogen water has an antioxidative effect on cells, tissues, and organs as well as a beneficial role in the prevention against oxidative stress-related disorders. However, the exact mechanism by which the hydrogen water reacts with bacterial membrane is beyond the scope of this study.
Why These Findings Matter
These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study and contribute to the growing body of molecular-hydrogen research.
How Strong Is This Evidence?
This is human clinical evidence from a human clinical study. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.
Technical Study Details
H2HUBB classifies this publication as human clinical study with human clinical evidence. The research population or model was 20 patients. The reported sample size was 20. The study used a human clinical study. The hydrogen delivery method was hydrogen-rich water. The source-reported hydrogen exposure was 1 mL hydrogen-rich water per reported dose; dissolved H₂ concentration was not sufficiently reported, so H2HUBB did not estimate milligrams of H₂.
Limitations and Safety
No separate limitations or safety findings were identified in the source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.