Hydrogen: A Potential New Adjuvant Therapy for COVID-19 Patients.
Fuxun Yang, Ruiming Yue, Xiaoxiu Luo, Rongan Liu, Xiaobo Huang · Frontiers in pharmacology · 2020
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
Based on a review of the research, the use of hydrogen might reduce the destructive cytokine storm and lung injury caused by SARS-CoV-2 during COVID-19 (Corona Virus Disease 2019) in the early stage, stimulating ropy sputum drainage, and ultimately reducing the incidence of severe disease. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
What the Findings Mean
H2HUBB reviewed how hydrogen-rich water was evaluated in this publication and summarizes the source-grounded findings below. 2% H₂ gas can be carefully administered in a hospital ( Tamura et al., 2017 ).
What Effects Did Molecular Hydrogen Have?
Breathing H₂ -O₂ might reduce the inspiratory effort in patients with acute severe tracheal stenosis and can be used safely for this purpose ( Zhou et al., 2019 ). In summary, the researchers hypothesize that the early use of hydrogen might mitigate the destruction caused by the cytokine storm associated with COVID-19, reducing lung injury, promoting viscous sputum drainage, and thus reducing the incidence of critically ill patients. 2% H₂ gas can be carefully administered in a hospital ( Tamura et al., 2017 ). Hydrogen has been shown to have antioxidant, anti-inflammatory, hormone-regulating, and apoptosis-resistance properties, among others.
Why These Findings Matter
These findings add evidence supporting molecular hydrogen's therapeutic potential within the biological process and outcomes directly measured in this publication and contribute to the growing body of molecular-hydrogen research.
How Strong Is This Evidence?
H2HUBB classifies this publication as other research and interprets only the outcomes directly supported by the source record.
Technical Study Details
H2HUBB classifies this publication as other research with other supported evidence. The reported sample size was 19. The hydrogen delivery method was hydrogen-rich water.
Limitations and Safety
No separate limitations or safety findings were identified in the current-study source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.
What the Researchers Studied
The available source identifies this publication as other research. A more specific population or model was not separately reported in the source text available to H2HUBB.