Saturated hydrogen improves lipid metabolism disorders and dysbacteriosis induced by a high-fat diet.
Xiangjie Qiu, Qiaona Ye, Mengxing Sun, Lili Wang, Yurong Tan, Guojun Wu · Experimental biology and medicine (Maywood, N.J.) · 2020
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Independent study record
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H2HUBB TAKEAWAY
In mice, treatment of mice with saturated hydrogen led to decreased total cholesterol, total glyceride, and low-density lipoprotein and increased high-density lipoprotein in the peripheral blood. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
What the Researchers Studied
The study examined mice.
How Molecular Hydrogen Was Used
Promising, though, is that saturated hydrogen can effectively improve the occurrence and development of metabolic diseases, such as obesity. However, the specific mechanism of how saturated hydrogen operates is still not very clear. Treatment of mice with saturated hydrogen led to decreased total cholesterol, total glyceride, and low-density lipoprotein and increased high-density lipoprotein in the peripheral blood.
What the Researchers Found
Treatment of mice with saturated hydrogen led to decreased total cholesterol, total glyceride, and low-density lipoprotein and increased high-density lipoprotein in the peripheral blood.
H₂ Mechanisms / Biological Findings
However, the specific mechanism of how saturated hydrogen operates is still not very clear. IMPACT STATEMENT: Past studies have shown that hydrogen can improve metabolic disorders, but its mechanism of action remains unclear.
Authors’ Conclusion
The authors concluded that these results suggest that saturated hydrogen could improve intestinal structural integrity and lipid metabolism disorders by inhibiting the glyoxylic acid cycle of the intestinal flora.