Hydrogen Gas as an Exotic Performance-Enhancing Agent: Challenges and Opportunities.
Sergej M Ostojic · Current pharmaceutical design · 2021
Research-use notice
Independent study record
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H2HUBB TAKEAWAY
In a laboratory model, either administered as an inhalational gas, enteral hydrogen-rich water, or intravenous hydrogen-rich water, H₂ seems to favorably affect various exercise performance outcomes and biomarkers of exercise-associated fatigue, inflammation, and oxidative stress. The authors concluded that H₂ is a newfangled and rather effective performance-enhancing agent, yet its promising ergogenic potency has to be further validated and characterized in more well-controlled, appropriately sampled and longterm mechanistic trials. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to determine clinical relevance.
What the Researchers Tested
Up to this point, H₂ was scrutinized for more than 170 different disease models and pathologies, and many research groups across the world have lately started to dynamically investigate its conceivable performance-enhancing potential.
How Molecular Hydrogen Was Used
The researchers outlined here the studies indexed in leading research databases (PubMed, Web of Science, SCOPUS, JSTORE) that explored the effects of hydrogen on exercise performance, and also addressed important restraints, open questions, and windows of opportunities for forthcoming research and possible H₂ enactment in exercise physiology. About two dozen trials have been identified in this domain, with most of the trials published during the past 5 years, while drinking hydrogen-rich water recognized as the most convenient method to deliver H₂ in both animal and human studies.
What Molecular Hydrogen Changed
Either administered as an inhalational gas, enteral hydrogen-rich water, or intravenous hydrogen-rich water, H₂ seems to favorably affect various exercise performance outcomes and biomarkers of exercise-associated fatigue, inflammation, and oxidative stress.
Proposed Mechanism
Either administered as an inhalational gas, enteral hydrogen-rich water, or intravenous hydrogen-rich water, H₂ seems to favorably affect various exercise performance outcomes and biomarkers of exercise-associated fatigue, inflammation, and oxidative stress. Either administered as an inhalational gas, enteral hydrogen-rich water, or intravenous hydrogen-rich water, H₂ seems to favorably affect various exercise performance outcomes and biomarkers of exercise-associated fatigue, inflammation, and oxidative stress.
Authors’ Conclusion
These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to determine clinical relevance.