Pectin and high-amylose maize starch increase caecal hydrogen production and relieve hepatic ischaemia-reperfusion injury in rats.
Naomichi Nishimura, Hiroki Tanabe, Yumi Sasaki, Yui Makita, Misako Ohata, Saori Yokoyama, Mami Asano, Tatsuro Yamamoto, Shuhachi Kiriyama · The British journal of nutrition · 2012
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
In male Sprague-Dawley rats,, the researchers found that Pec or HAS, which enhance H₂ generation in the large intestine, alleviated hepatic IR injury. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
What the Researchers Studied
The study examined male Sprague-Dawley rats.
How Molecular Hydrogen Was Used
Molecular hydrogen was administered as portal h₂ concentration showed a significant dose-dependent increase with the amount of pec or has supplementation. , the researchers found that pec or has, which enhance h₂ generation in the large intestine, alleviated hepatic ir injury.
What the Researchers Found
Portal H₂ concentration showed a significant dose-dependent increase with the amount of Pec or HAS supplementation.
H₂ Mechanisms / Biological Findings
The source material reviewed did not establish a specific molecular hydrogen mechanism for the reported findings.
Authors’ Conclusion
The authors concluded that , the researchers found that Pec or HAS, which enhance H₂ generation in the large intestine, alleviated hepatic IR injury.