Hydrogen Research Study
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Human clinical evidenceHuman Clinical Studyhydrogen-rich water

Hydrogen-rich water affected blood alkalinity in physically active men.

Sergej M Ostojic, Marko D Stojanovic · Research in sports medicine (Print) · 2014

Research-use notice

Independent study record

Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

H2HUBB Research Library branded molecular hydrogen research image
Primary topic Blood Pressure and Vascular Function
Evidence type Human clinical evidence
Publication type Human Clinical Study
Hydrogen method hydrogen-rich water

H2HUBB TAKEAWAY

In 52 physically active, healthy participants, intake of HRW significantly increased fasting arterial blood pH by 0.04 (95% confidence interval; 0.01 – 0.08; p < 0.001), and postexercise pH by 0.07 (95% confidence interval; 0.01 – 0.10; p = 0.03) after 14 days of intervention. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.

What the Findings Mean

H2HUBB reviewed how hydrogen-rich water affected the outcomes measured in 52 physically active, healthy participants. Intake of HRW significantly increased fasting arterial blood pH by 0.04 (95% confidence interval; 0.01 – 0.08; p < 0.001), and postexercise pH by 0.07 (95% confidence interval; 0.01 – 0.10; p = 0.03) after 14 days of intervention.

What the Researchers Studied

The researchers studied 52 physically active, healthy participants. The study used a randomized, placebo-controlled human clinical trial. The comparison condition was placebo.

What Effects Did Molecular Hydrogen Have?

2 L hydrogen-rich water per reported dose; dissolved H₂ concentration was not reported in the available source text, so H2HUBB did not estimate milligrams of H₂; reported treatment duration: 14 days. Intake of HRW significantly increased fasting arterial blood pH by 0.04 (95% confidence interval; 0.01 – 0.08; p < 0.001), and postexercise pH by 0.07 (95% confidence interval; 0.01 – 0.10; p = 0.03) after 14 days of intervention.

Why These Findings Matter

These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study and contribute to the growing body of molecular-hydrogen research.

How Strong Is This Evidence?

This is human clinical evidence from a randomized, placebo-controlled human clinical trial. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.

Technical Study Details

H2HUBB classifies this publication as human clinical study with human clinical evidence. The research population or model was 52 physically active, healthy participants. The reported sample size was 6. The study used a randomized, placebo-controlled human clinical trial. The hydrogen delivery method was hydrogen-rich water. H2HUBB translates the reported hydrogen dose as 2 L hydrogen-rich water per reported dose; dissolved H₂ concentration was not reported in the available source text, so H2HUBB did not estimate milligrams of H₂. The reported treatment duration was 14 days.

Limitations and Safety

No separate limitations or safety findings were identified in the source text available to H2HUBB.

Original Study and H2HUBB Research Context

H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.